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Renal interstitial non-necrotizing granulomas

MedGen UID:
1716113
Concept ID:
C5397660
Pathologic Function
Synonym: Renal interstitial non-necrotizing granulomata
 
HPO: HP:0032643

Definition

Interstital aggregates of histiciocytes, occasionally multinucleated with associated lymphoplasmacytic and occasionally eosinophilic inflammation. Organization can range from poorly-to-well defined and multinucleated giant cells may be present with no necrosis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal interstitial non-necrotizing granulomas

Recent clinical studies

Diagnosis

Mocanu A, Bogos RA, Trandafir LM, Cojocaru E, Ioniuc I, Alecsa M, Lupu VV, Miron L, Lazaruc TI, Lupu A, Miron IC, Starcea IM
Int J Mol Sci 2023 Apr 15;24(8) doi: 10.3390/ijms24087327. PMID: 37108489Free PMC Article
Travis WD, Hoffman GS, Leavitt RY, Pass HI, Fauci AS
Am J Surg Pathol 1991 Apr;15(4):315-33. doi: 10.1097/00000478-199104000-00001. PMID: 2006712

Therapy

Fervenza FC, Kanakiriya S, Kunau RT, Gibney R, Lager DJ
Am J Kidney Dis 2000 Nov;36(5):1034-40. doi: 10.1053/ajkd.2000.19107. PMID: 11054362

Clinical prediction guides

Travis WD, Hoffman GS, Leavitt RY, Pass HI, Fauci AS
Am J Surg Pathol 1991 Apr;15(4):315-33. doi: 10.1097/00000478-199104000-00001. PMID: 2006712

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