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Renal tubular epithelial cell cytoplasmic vacuolization

MedGen UID:
1717347
Concept ID:
C5397618
Finding
HPO: HP:0032596

Definition

Tubular cross section with intracytoplasmic vacuoles in at least one tubular epithelial cell. This feature is classified as isometric when vacuoles are round and similar in size and coarse when vacuoles were not round in shape or varied in size. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal tubular epithelial cell cytoplasmic vacuolization

Professional guidelines

PubMed

Shi Y, Tao M, Ma X, Hu Y, Huang G, Qiu A, Zhuang S, Liu N
Cell Death Dis 2020 Jun 17;11(6):467. doi: 10.1038/s41419-020-2673-z. PMID: 32555189Free PMC Article
Sayeed S, Lindsey KG, Baras AS, Jackson C, Powers CN, Uram-Tuculescu C, Smith SC
Cancer Cytopathol 2016 Aug;124(8):565-72. Epub 2016 Apr 7 doi: 10.1002/cncy.21721. PMID: 27062008

Recent clinical studies

Etiology

Auld FM, Parai JL, Milroy CM
J Forensic Sci 2023 Sep;68(5):1759-1767. Epub 2023 Jul 6 doi: 10.1111/1556-4029.15321. PMID: 37409637
Nakamura J, Yamamoto T, Takabatake Y, Namba-Hamano T, Minami S, Takahashi A, Matsuda J, Sakai S, Yonishi H, Maeda S, Matsui S, Matsui I, Hamano T, Takahashi M, Goto M, Izumi Y, Bamba T, Sasai M, Yamamoto M, Matsusaka T, Niimura F, Yanagita M, Nakamura S, Yoshimori T, Ballabio A, Isaka Y
JCI Insight 2023 Feb 22;8(4) doi: 10.1172/jci.insight.162498. PMID: 36649084Free PMC Article
Shi J, Qian J, Li H, Luo H, Luo W, Lin Z
Ren Fail 2018 Nov;40(1):85-91. doi: 10.1080/0886022X.2017.1419973. PMID: 29299951Free PMC Article
Zhou C, Yool AJ, Byard RW
J Forensic Sci 2017 May;62(3):681-685. Epub 2017 Jan 30 doi: 10.1111/1556-4029.13311. PMID: 28133737
Zhou C, Byard RW
Forensic Sci Int 2011 Mar 20;206(1-3):e82-4. Epub 2010 Sep 27 doi: 10.1016/j.forsciint.2010.08.018. PMID: 20875709

Diagnosis

Auld FM, Parai JL, Milroy CM
J Forensic Sci 2023 Sep;68(5):1759-1767. Epub 2023 Jul 6 doi: 10.1111/1556-4029.15321. PMID: 37409637
Zhou C, Yool AJ, Byard RW
J Forensic Sci 2017 May;62(3):681-685. Epub 2017 Jan 30 doi: 10.1111/1556-4029.13311. PMID: 28133737
Zhou C, Moore L, Yool A, Jaunzems A, Byard RW
J Forensic Sci 2015 May;60(3):638-41. Epub 2015 Feb 12 doi: 10.1111/1556-4029.12711. PMID: 25684621
Zhou C, Byard RW
J Forensic Sci 2012 Jan;57(1):126-8. Epub 2011 Nov 10 doi: 10.1111/j.1556-4029.2011.01957.x. PMID: 22074296
Zhou C, Byard RW
Forensic Sci Int 2011 Mar 20;206(1-3):e82-4. Epub 2010 Sep 27 doi: 10.1016/j.forsciint.2010.08.018. PMID: 20875709

Therapy

Wan Y, Yu Y, Yu C, Luo J, Wen S, Shen L, Wei G, Hua Y
Ren Fail 2023 Dec;45(1):2221138. doi: 10.1080/0886022X.2023.2221138. PMID: 37293812Free PMC Article
Nakamura J, Yamamoto T, Takabatake Y, Namba-Hamano T, Minami S, Takahashi A, Matsuda J, Sakai S, Yonishi H, Maeda S, Matsui S, Matsui I, Hamano T, Takahashi M, Goto M, Izumi Y, Bamba T, Sasai M, Yamamoto M, Matsusaka T, Niimura F, Yanagita M, Nakamura S, Yoshimori T, Ballabio A, Isaka Y
JCI Insight 2023 Feb 22;8(4) doi: 10.1172/jci.insight.162498. PMID: 36649084Free PMC Article
Watanabe S, Sawa N, Mizuno H, Yamanouchi M, Suwabe T, Hoshino J, Kinowaki K, Ohashi K, Fujii T, Yamaguchi Y, Ubara Y
CEN Case Rep 2021 Nov;10(4):563-569. Epub 2021 May 22 doi: 10.1007/s13730-021-00609-7. PMID: 34021486Free PMC Article
Shi Y, Tao M, Ma X, Hu Y, Huang G, Qiu A, Zhuang S, Liu N
Cell Death Dis 2020 Jun 17;11(6):467. doi: 10.1038/s41419-020-2673-z. PMID: 32555189Free PMC Article
Singh L, Singh G, Sharma A, Sinha A, Bagga A, Dinda AK
Hum Pathol 2015 Jan;46(1):34-9. Epub 2014 Oct 2 doi: 10.1016/j.humpath.2014.09.003. PMID: 25449629

Prognosis

Natanti A, Mazzanti R, Palpacelli M, Turchi C, Tagliabracci A, Pesaresi M
Med Sci Law 2021 Jan;61(1_suppl):36-41. doi: 10.1177/0025802420942423. PMID: 33591877
Xia QY, Wang Z, Chen N, Gan HL, Teng XD, Shi SS, Wang X, Wei X, Ye SB, Li R, Ma HH, Lu ZF, Zhou XJ, Rao Q
Mod Pathol 2017 Mar;30(3):416-426. Epub 2016 Dec 9 doi: 10.1038/modpathol.2016.204. PMID: 27934879
Zhou C, Byard RW
J Forensic Sci 2017 Jan;62(1):122-125. Epub 2016 Dec 8 doi: 10.1111/1556-4029.13245. PMID: 27930814
Sayeed S, Lindsey KG, Baras AS, Jackson C, Powers CN, Uram-Tuculescu C, Smith SC
Cancer Cytopathol 2016 Aug;124(8):565-72. Epub 2016 Apr 7 doi: 10.1002/cncy.21721. PMID: 27062008
Oda T, Hotta O, Taguma Y, Kitamura H, Sugai H, Onodera S, Horigome I, Suzuki K, Shouji Y, Furuta T, Chiba S, Yoshizawa N, Nagura H
Kidney Int 1998 May;53(5):1190-200. doi: 10.1046/j.1523-1755.1998.00886.x. PMID: 9573533

Clinical prediction guides

Liu D, Lei J, Huang K, Yin G
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Mar 28;46(3):221-226. doi: 10.11817/j.issn.1672-7347.2021.190299. PMID: 33927067Free PMC Article
Tan J, Xie Q, Song S, Miao Y, Zhang Q
Med Sci Monit 2018 Mar 1;24:1258-1267. doi: 10.12659/msm.907718. PMID: 29494565Free PMC Article
Shi J, Qian J, Li H, Luo H, Luo W, Lin Z
Ren Fail 2018 Nov;40(1):85-91. doi: 10.1080/0886022X.2017.1419973. PMID: 29299951Free PMC Article
Zhou C, Yool AJ, Byard RW
J Forensic Sci 2017 May;62(3):681-685. Epub 2017 Jan 30 doi: 10.1111/1556-4029.13311. PMID: 28133737
Zhou C, Moore L, Yool A, Jaunzems A, Byard RW
J Forensic Sci 2015 May;60(3):638-41. Epub 2015 Feb 12 doi: 10.1111/1556-4029.12711. PMID: 25684621

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