Combined BAP1-Inactivated Nevus

MedGen UID:: 1719884
•Concept ID:: C5237243
•: Neoplastic Process

Synonym:

Wiesner Nevus

Definition

A combined nevus with a spitzoid component and inactivation of BAP1. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCombined BAP1-Inactivated Nevus

Disease
- Neoplasm
  - Neoplasm by Morphology
    - Melanocytic neoplasm
      - Melanocytic skin neoplasm
        BAP1-Inactivated Skin Melanocytic Neoplasm
        Combined BAP1-Inactivated Nevus

Recent clinical studies

Etiology

Novel insights into the BAP1-inactivated melanocytic tumor.

Donati M, Martinek P, Steiner P, Grossmann P, Vanecek T, Kastnerova L, Kolm I, Baneckova M, Donati P, Kletskaya I, Kalmykova A, Feit J, Blasch P, Szilagyi D, Baldi A, Persichetti P, Crescenzi A, Michal M, Kazakov DV
Mod Pathol 2022 May;35(5):664-675. Epub 2021 Dec 2 doi: 10.1038/s41379-021-00976-7. PMID: 34857909

BAP1-inactivated melanocytic tumour with borderline histopathological features (BAP1-inactivated melanocytoma): A case report and a reappraisal.

Ferrara G, Mariani MP, Auriemma M
Australas J Dermatol 2021 Feb;62(1):e88-e91. Epub 2020 Jul 20 doi: 10.1111/ajd.13408. PMID: 33107024

RAF1 Gene Fusions as a Possible Driver Mechanism in Rare BAP1-Inactivated Melanocytic Tumors: A Report of 2 Cases.

Donati M, Martinek P, Kastnerova L, Persichetti P, Michal M, Kazakov DV
Am J Dermatopathol 2020 Dec;42(12):961-966. doi: 10.1097/DAD.0000000000001740. PMID: 32769548

See all (3)