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Agnosia

MedGen UID:
174
•Concept ID:
C0001816
•
Mental or Behavioral Dysfunction
Synonyms: Monomodal visual amnesia; Primary visual agnosia; Visual amnesia
SNOMED CT: Agnosia (42341009); Loss of perception of sensory stimuli (42341009)
 
HPO: HP:0010524
Monarch Initiative: MONDO:0005638

Definition

Alteration or impairment in the processing or interpretation of sensory information can lead to abnormal perceptions or experiences. [from HPO]

Professional guidelines

PubMed

New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications.
Chare L, Hodges JR, Leyton CE, McGinley C, Tan RH, Kril JJ, Halliday GM
J Neurol Neurosurg Psychiatry 2014 Aug;85(8):865-70. Epub 2014 Jan 13 doi: 10.1136/jnnp-2013-306948. PMID: 24421286
Management of Landau-Kleffner syndrome.
Mikati MA, Shamseddine AN
Paediatr Drugs 2005;7(6):377-89. doi: 10.2165/00148581-200507060-00006. PMID: 16356025
Clinical management of agnosia.
Burns MS
Top Stroke Rehabil 2004 Winter;11(1):1-9. doi: 10.1310/N13K-YKYQ-3XX1-NFAV. PMID: 14872395

Recent clinical studies

Etiology

Effects of esketamine on analgesia and postpartum depression after cesarean section: A randomized, double-blinded controlled trial.
Wang W, Xu H, Ling B, Chen Q, Lv J, Yu W
Medicine (Baltimore) 2022 Nov 25;101(47):e32010. doi: 10.1097/MD.0000000000032010. PMID: 36451452Free PMC Article
Regression in children with epilepsy.
Camfield P, Camfield C
Neurosci Biobehav Rev 2019 Jan;96:210-218. Epub 2018 Dec 8 doi: 10.1016/j.neubiorev.2018.12.008. PMID: 30537476
The Visual Agnosias and Related Disorders.
Haque S, Vaphiades MS, Lueck CJ
J Neuroophthalmol 2018 Sep;38(3):379-392. doi: 10.1097/WNO.0000000000000556. PMID: 28945627
Molecular mechanisms underlying neurodevelopmental disorders, ADHD and autism.
Bădescu GM, Fîlfan M, Sandu RE, Surugiu R, Ciobanu O, Popa-Wagner A
Rom J Morphol Embryol 2016;57(2):361-6. PMID: 27516006
Recognizing faces.
Ellis HD
Br J Psychol 1975 Nov;66(4):409-26. doi: 10.1111/j.2044-8295.1975.tb01477.x. PMID: 1106805

Diagnosis

Spatial Neglect and Anosognosia After Right Brain Stroke.
Barrett AM
Continuum (Minneap Minn) 2021 Dec 1;27(6):1624-1645. doi: 10.1212/CON.0000000000001076. PMID: 34881729Free PMC Article
Color vision.
Carroll J, Conway BR
Handb Clin Neurol 2021;178:131-153. doi: 10.1016/B978-0-12-821377-3.00005-2. PMID: 33832674
History of Anosognosia.
Gainotti G
Front Neurol Neurosci 2019;44:75-82. Epub 2019 Apr 30 doi: 10.1159/000494954. PMID: 31220837
Anosognosia.
Mograbi DC, Morris RG
Cortex 2018 Jun;103:385-386. Epub 2018 Apr 12 doi: 10.1016/j.cortex.2018.04.001. PMID: 29731103
Auditory agnosia.
Slevc LR, Shell AR
Handb Clin Neurol 2015;129:573-87. doi: 10.1016/B978-0-444-62630-1.00032-9. PMID: 25726291

Therapy

Effects of esketamine on analgesia and postpartum depression after cesarean section: A randomized, double-blinded controlled trial.
Wang W, Xu H, Ling B, Chen Q, Lv J, Yu W
Medicine (Baltimore) 2022 Nov 25;101(47):e32010. doi: 10.1097/MD.0000000000032010. PMID: 36451452Free PMC Article
Spatial Neglect and Anosognosia After Right Brain Stroke.
Barrett AM
Continuum (Minneap Minn) 2021 Dec 1;27(6):1624-1645. doi: 10.1212/CON.0000000000001076. PMID: 34881729Free PMC Article
Optogenetics: Therapeutic spark in neuropathic pain.
Liu K, Wang L
Bosn J Basic Med Sci 2019 Nov 8;19(4):321-327. doi: 10.17305/bjbms.2019.4114. PMID: 30995901Free PMC Article
Tic disorders.
Martino D, Mink JW
Continuum (Minneap Minn) 2013 Oct;19(5 Movement Disorders):1287-311. doi: 10.1212/01.CON.0000436157.31662.af. PMID: 24092291
Management of Landau-Kleffner syndrome.
Mikati MA, Shamseddine AN
Paediatr Drugs 2005;7(6):377-89. doi: 10.2165/00148581-200507060-00006. PMID: 16356025

Prognosis

Overview of COVID-19 and neurological complications.
Hosseini N, Nadjafi S, Ashtary B
Rev Neurosci 2021 Aug 26;32(6):671-691. Epub 2021 Feb 15 doi: 10.1515/revneuro-2020-0116. PMID: 33583157
Anosognosia in Dementia.
Wilson RS, Sytsma J, Barnes LL, Boyle PA
Curr Neurol Neurosci Rep 2016 Sep;16(9):77. doi: 10.1007/s11910-016-0684-z. PMID: 27438597
Insight in Psychiatry and Neurology: State of the Art, and Hypotheses.
Landi P, Marazziti D, Rutigliano G, Dell'Osso L
Harv Rev Psychiatry 2016 May-Jun;24(3):214-28. doi: 10.1097/HRP.0000000000000083. PMID: 27075815
Post-stroke language disorders.
Sinanović O, Mrkonjić Z, Zukić S, Vidović M, Imamović K
Acta Clin Croat 2011 Mar;50(1):79-94. PMID: 22034787
Are there lexicons?
Coltheart M
Q J Exp Psychol A 2004 Oct;57(7):1153-71. doi: 10.1080/02724980443000007. PMID: 15513241

Clinical prediction guides

Emotional Deprivation in Children: Growth Faltering and Reversible Hypopituitarism.
Rogol AD
Front Endocrinol (Lausanne) 2020;11:596144. Epub 2020 Oct 7 doi: 10.3389/fendo.2020.596144. PMID: 33117295Free PMC Article
Hemineglect and Attentional Dysfunction.
Langer KG, Piechowski-Jozwiak B, Bogousslavsky J
Front Neurol Neurosci 2019;44:89-99. Epub 2019 Apr 30 doi: 10.1159/000494956. PMID: 31220845
History of Anosognosia.
Gainotti G
Front Neurol Neurosci 2019;44:75-82. Epub 2019 Apr 30 doi: 10.1159/000494954. PMID: 31220837
Apraxia, Neglect, and Agnosia.
Coslett HB
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):768-782. doi: 10.1212/CON.0000000000000606. PMID: 29851877
Rise and fall of the two visual systems theory.
Rossetti Y, Pisella L, McIntosh RD
Ann Phys Rehabil Med 2017 Jun;60(3):130-140. Epub 2017 May 23 doi: 10.1016/j.rehab.2017.02.002. PMID: 28545844

Recent systematic reviews

Altered awareness of cognitive and neuropsychiatric symptoms in Parkinson's disease and Dementia with Lewy Bodies: A systematic review.
Pennington C, Duncan G, Ritchie C
Int J Geriatr Psychiatry 2021 Jan;36(1):15-30. Epub 2020 Sep 14 doi: 10.1002/gps.5415. PMID: 32869379
Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, Laske C, Martins RN, Masters CL, Mayeux RP, Ringman JM, Rossor MN, Salloway SP, Schofield PR, Morris JC, Bateman RJ; Dominantly Inherited Alzheimer Network (DIAN)
Lancet Neurol 2016 Dec;15(13):1317-1325. Epub 2016 Oct 21 doi: 10.1016/S1474-4422(16)30229-0. PMID: 27777020Free PMC Article
A Systematic Review of Metacognitive Differences Between Alzheimer's Disease and Frontotemporal Dementia.
DeLozier SJ, Davalos D
Am J Alzheimers Dis Other Demen 2016 Aug;31(5):381-8. Epub 2015 Dec 24 doi: 10.1177/1533317515618899. PMID: 26705377
Posterior cortical atrophy and Alzheimer's disease: a meta-analytic review of neuropsychological and brain morphometry studies.
Alves J, Soares JM, Sampaio A, Gonçalves OF
Brain Imaging Behav 2013 Sep;7(3):353-61. doi: 10.1007/s11682-013-9236-1. PMID: 23690254
Anosognosia after stroke: assessment, occurrence, subtypes and impact on functional outcome reviewed.
Jehkonen M, Laihosalo M, Kettunen J
Acta Neurol Scand 2006 Nov;114(5):293-306. doi: 10.1111/j.1600-0404.2006.00723.x. PMID: 17022776

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