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COVID-19-Associated Coagulation Disorder

MedGen UID:
1747147
•Concept ID:
C5419174
•
Disease or Syndrome
Synonyms: COVID-19-Associated Coagulopathy; SARS-CoV-2-Associated Coagulation Disorder; SARS-CoV-2-Associated Coagulopathy

Definition

Coagulation disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19-Associated Coagulation Disorder

Professional guidelines

PubMed

COVID-19 associated coagulopathy: Mechanisms and host-directed treatment.
Plášek J, Gumulec J, Máca J, Škarda J, Procházka V, Grézl T, Václavík J
Am J Med Sci 2022 Jun;363(6):465-475. Epub 2021 Nov 6 doi: 10.1016/j.amjms.2021.10.012. PMID: 34752741Free PMC Article
Prophylaxis and treatment of COVID-19 related venous thromboembolism.
Kaptein FHJ, Stals MAM, Huisman MV, Klok FA
Postgrad Med 2021 Aug;133(sup1):27-35. Epub 2021 Mar 4 doi: 10.1080/00325481.2021.1891788. PMID: 33657964Free PMC Article
Proposal for the management of COVID-19-associated coagulopathy in children.
Ávila-Castro D, Ortiz-Torres G, Sánchez-Jara B, Valle-Cárdenas T, Aquino-Fernández E, González-Ávila AI, Majluf-Cruz A
Gac Med Mex 2020;156(4):344-353. doi: 10.24875/GMM.20000418. PMID: 32831339

Recent clinical studies

Etiology

COVID-19: coagulation disorders and anticoagulant treatment in patients hospitalised in ICU.
Pluta J, Cieniewicz A, Trzebicki J
Anaesthesiol Intensive Ther 2021;53(2):153-161. doi: 10.5114/ait.2021.105783. PMID: 34006056Free PMC Article
Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives.
Genovese G, Moltrasio C, Berti E, Marzano AV
Dermatology 2021;237(1):1-12. Epub 2020 Nov 24 doi: 10.1159/000512932. PMID: 33232965Free PMC Article
COVID-19-associated coagulopathy.
Franchini M, Marano G, Cruciani M, Mengoli C, Pati I, Masiello F, Veropalumbo E, Pupella S, Vaglio S, Liumbruno GM
Diagnosis (Berl) 2020 Nov 18;7(4):357-363. doi: 10.1515/dx-2020-0078. PMID: 32683333
Acute kidney injury in critically ill patients with COVID-19.
Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L
Intensive Care Med 2020 Jul;46(7):1339-1348. Epub 2020 Jun 12 doi: 10.1007/s00134-020-06153-9. PMID: 32533197Free PMC Article
COVID-19 update: Covid-19-associated coagulopathy.
Becker RC
J Thromb Thrombolysis 2020 Jul;50(1):54-67. doi: 10.1007/s11239-020-02134-3. PMID: 32415579Free PMC Article

Diagnosis

COVID-19-associated coagulopathy and antithrombotic agents-lessons after 1 year.
Leentjens J, van Haaps TF, Wessels PF, Schutgens REG, Middeldorp S
Lancet Haematol 2021 Jul;8(7):e524-e533. Epub 2021 Apr 27 doi: 10.1016/S2352-3026(21)00105-8. PMID: 33930350Free PMC Article
COVID-19-associated coagulopathy and disseminated intravascular coagulation.
Asakura H, Ogawa H
Int J Hematol 2021 Jan;113(1):45-57. Epub 2020 Nov 7 doi: 10.1007/s12185-020-03029-y. PMID: 33161508Free PMC Article
COVID-19-associated coagulopathy.
Franchini M, Marano G, Cruciani M, Mengoli C, Pati I, Masiello F, Veropalumbo E, Pupella S, Vaglio S, Liumbruno GM
Diagnosis (Berl) 2020 Nov 18;7(4):357-363. doi: 10.1515/dx-2020-0078. PMID: 32683333
COVID-19 Associated Hemophagocytic Lymphohistiocytosis and Coagulopathy: Targeting the Duumvirate.
Bhattacharjee S, Banerjee M, Pal R
Indian Pediatr 2020 Sep 15;57(9):827-833. Epub 2020 Jun 24 doi: 10.1007/s13312-020-1962-z. PMID: 32583809Free PMC Article
COVID-19-associated coagulopathy: An exploration of mechanisms.
Colling ME, Kanthi Y
Vasc Med 2020 Oct;25(5):471-478. Epub 2020 Jun 19 doi: 10.1177/1358863X20932640. PMID: 32558620Free PMC Article

Therapy

COVID-19 associated coagulopathy: Mechanisms and host-directed treatment.
Plášek J, Gumulec J, Máca J, Škarda J, Procházka V, Grézl T, Václavík J
Am J Med Sci 2022 Jun;363(6):465-475. Epub 2021 Nov 6 doi: 10.1016/j.amjms.2021.10.012. PMID: 34752741Free PMC Article
COVID-19-associated coagulopathy and antithrombotic agents-lessons after 1 year.
Leentjens J, van Haaps TF, Wessels PF, Schutgens REG, Middeldorp S
Lancet Haematol 2021 Jul;8(7):e524-e533. Epub 2021 Apr 27 doi: 10.1016/S2352-3026(21)00105-8. PMID: 33930350Free PMC Article
COVID-19-associated coagulopathy and disseminated intravascular coagulation.
Asakura H, Ogawa H
Int J Hematol 2021 Jan;113(1):45-57. Epub 2020 Nov 7 doi: 10.1007/s12185-020-03029-y. PMID: 33161508Free PMC Article
COVID-19-associated coagulopathy.
Franchini M, Marano G, Cruciani M, Mengoli C, Pati I, Masiello F, Veropalumbo E, Pupella S, Vaglio S, Liumbruno GM
Diagnosis (Berl) 2020 Nov 18;7(4):357-363. doi: 10.1515/dx-2020-0078. PMID: 32683333
COVID-19 update: Covid-19-associated coagulopathy.
Becker RC
J Thromb Thrombolysis 2020 Jul;50(1):54-67. doi: 10.1007/s11239-020-02134-3. PMID: 32415579Free PMC Article

Prognosis

COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications.
Lim MS, Mcrae S
Crit Rev Oncol Hematol 2021 Dec;168:103529. Epub 2021 Nov 17 doi: 10.1016/j.critrevonc.2021.103529. PMID: 34800652Free PMC Article
COVID-19-associated coagulopathy and antithrombotic agents-lessons after 1 year.
Leentjens J, van Haaps TF, Wessels PF, Schutgens REG, Middeldorp S
Lancet Haematol 2021 Jul;8(7):e524-e533. Epub 2021 Apr 27 doi: 10.1016/S2352-3026(21)00105-8. PMID: 33930350Free PMC Article
COVID-19-associated coagulopathy and disseminated intravascular coagulation.
Asakura H, Ogawa H
Int J Hematol 2021 Jan;113(1):45-57. Epub 2020 Nov 7 doi: 10.1007/s12185-020-03029-y. PMID: 33161508Free PMC Article
COVID-19-associated coagulopathy: An exploration of mechanisms.
Colling ME, Kanthi Y
Vasc Med 2020 Oct;25(5):471-478. Epub 2020 Jun 19 doi: 10.1177/1358863X20932640. PMID: 32558620Free PMC Article
Acute kidney injury in critically ill patients with COVID-19.
Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L
Intensive Care Med 2020 Jul;46(7):1339-1348. Epub 2020 Jun 12 doi: 10.1007/s00134-020-06153-9. PMID: 32533197Free PMC Article

Clinical prediction guides

Impaired coagulation, liver dysfunction and COVID-19: Discovering an intriguing relationship.
D'Ardes D, Boccatonda A, Cocco G, Fabiani S, Rossi I, Bucci M, Guagnano MT, Schiavone C, Cipollone F
World J Gastroenterol 2022 Mar 21;28(11):1102-1112. doi: 10.3748/wjg.v28.i11.1102. PMID: 35431501Free PMC Article
COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications.
Lim MS, Mcrae S
Crit Rev Oncol Hematol 2021 Dec;168:103529. Epub 2021 Nov 17 doi: 10.1016/j.critrevonc.2021.103529. PMID: 34800652Free PMC Article
COVID-19-associated coagulopathy: a concise review on pathogenesis and clinical implications.
Memar Montazerin S, Najafi H, Shojaei F, Chi G, Goudarzi S, Sharfaei S, Kahe F, Hassanzadeh S
Infez Med 2021 Mar 1;29(1):1-9. PMID: 33664168
COVID-19-associated coagulopathy: An exploration of mechanisms.
Colling ME, Kanthi Y
Vasc Med 2020 Oct;25(5):471-478. Epub 2020 Jun 19 doi: 10.1177/1358863X20932640. PMID: 32558620Free PMC Article
Acute kidney injury in critically ill patients with COVID-19.
Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L
Intensive Care Med 2020 Jul;46(7):1339-1348. Epub 2020 Jun 12 doi: 10.1007/s00134-020-06153-9. PMID: 32533197Free PMC Article

Recent systematic reviews

Tissue factor in COVID-19-associated coagulopathy.
Subramaniam S, Kothari H, Bosmann M
Thromb Res 2022 Dec;220:35-47. Epub 2022 Oct 1 doi: 10.1016/j.thromres.2022.09.025. PMID: 36265412Free PMC Article
COVID-19 and New Onset IgA Vasculitis: A Systematic Review of Case Reports.
Messova A, Pivina L, Muzdubayeva Z, Sanbayev D, Urazalina Z, Adams A
J Emerg Nurs 2022 Jul;48(4):348-365. Epub 2022 May 13 doi: 10.1016/j.jen.2022.05.002. PMID: 35691763Free PMC Article
COVID-19 associated with immune thrombocytopenia: a systematic review and meta-analysis.
Alharbi MG, Alanazi N, Yousef A, Alanazi N, Alotaibi B, Aljurf M, El Fakih R
Expert Rev Hematol 2022 Feb;15(2):157-166. Epub 2022 Feb 12 doi: 10.1080/17474086.2022.2029699. PMID: 35025706Free PMC Article
A Review of Pathophysiology, Clinical Features, and Management Options of COVID-19 Associated Coagulopathy.
Goswami J, MacArthur TA, Sridharan M, Pruthi RK, McBane RD 2nd, Witzig TE, Park MS
Shock 2021 Jun 1;55(6):700-716. doi: 10.1097/SHK.0000000000001680. PMID: 33378321Free PMC Article
Coagulation Dysfunction.
Fei Y, Tang N, Liu H, Cao W
Arch Pathol Lab Med 2020 Oct 1;144(10):1223-1229. doi: 10.5858/arpa.2020-0324-SA. PMID: 32551814

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