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COVID-19-Associated Acute Hemorrhagic Necrotizing Encephalitis

MedGen UID:
1768646
•Concept ID:
C5419167
•
Disease or Syndrome
Synonyms: COVID-19-Associated Acute Hemorrhagic Necrotizing Encephalopathy; SARS-CoV-2-Associated Acute Hemorrhagic Necrotizing Encephalitis; SARS-CoV-2-Associated Acute Hemorrhagic Necrotizing Encephalopathy

Definition

Acute hemorrhagic necrotizing encephalitis caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19-Associated Acute Hemorrhagic Necrotizing Encephalitis

Recent clinical studies

Etiology

Clinical characteristics and outcomes of COVID-19-associated encephalopathy in children.
Li L, Liao H, Kuang X, Jin K
J Neurovirol 2024 Apr;30(2):187-196. Epub 2024 Apr 3 doi: 10.1007/s13365-024-01202-1. PMID: 38570476
COVID-19-associated Diffuse Leukoencephalopathy and Microhemorrhages.
Radmanesh A, Derman A, Lui YW, Raz E, Loh JP, Hagiwara M, Borja MJ, Zan E, Fatterpekar GM
Radiology 2020 Oct;297(1):E223-E227. Epub 2020 May 21 doi: 10.1148/radiol.2020202040. PMID: 32437314Free PMC Article

Diagnosis

Central neuroinflammation in Covid-19: a systematic review of 182 cases with encephalitis, acute disseminated encephalomyelitis, and necrotizing encephalopathies.
Zamani R, Pouremamali R, Rezaei N
Rev Neurosci 2022 Jun 27;33(4):397-412. Epub 2021 Sep 17 doi: 10.1515/revneuro-2021-0082. PMID: 34536341
COVID-19 and neuroinflammation: a literature review of relevant neuroimaging and CSF markers in central nervous system inflammatory disorders from SARS-COV2.
Sriwastava S, Tandon M, Podury S, Prasad A, Wen S, Guthrie G, Kakara M, Jaiswal S, Subedi R, Elkhooly M, Lisak RP
J Neurol 2021 Dec;268(12):4448-4478. Epub 2021 May 19 doi: 10.1007/s00415-021-10611-9. PMID: 34009454Free PMC Article
COVID-19: Neuroimaging Features of a Pandemic.
Ladopoulos T, Zand R, Shahjouei S, Chang JJ, Motte J, Charles James J, Katsanos AH, Kerro A, Farahmand G, Vaghefi Far A, Rahimian N, Ebrahimzadeh SA, Abedi V, Papathanasiou M, Labedi A, Schneider R, Lukas C, Tsiodras S, Tsivgoulis G, Krogias C
J Neuroimaging 2021 Mar;31(2):228-243. Epub 2021 Jan 9 doi: 10.1111/jon.12819. PMID: 33421032Free PMC Article

Prognosis

Clinical characteristics and outcomes of COVID-19-associated encephalopathy in children.
Li L, Liao H, Kuang X, Jin K
J Neurovirol 2024 Apr;30(2):187-196. Epub 2024 Apr 3 doi: 10.1007/s13365-024-01202-1. PMID: 38570476

Clinical prediction guides

COVID-19 and neuroinflammation: a literature review of relevant neuroimaging and CSF markers in central nervous system inflammatory disorders from SARS-COV2.
Sriwastava S, Tandon M, Podury S, Prasad A, Wen S, Guthrie G, Kakara M, Jaiswal S, Subedi R, Elkhooly M, Lisak RP
J Neurol 2021 Dec;268(12):4448-4478. Epub 2021 May 19 doi: 10.1007/s00415-021-10611-9. PMID: 34009454Free PMC Article
Neuroimaging Patterns in Patients with COVID-19-Associated Neurological Complications: A Review.
Garg RK, Paliwal VK, Malhotra HS, Sharma PK
Neurol India 2021 Mar-Apr;69(2):260-271. doi: 10.4103/0028-3886.314531. PMID: 33904434
COVID-19: Neuroimaging Features of a Pandemic.
Ladopoulos T, Zand R, Shahjouei S, Chang JJ, Motte J, Charles James J, Katsanos AH, Kerro A, Farahmand G, Vaghefi Far A, Rahimian N, Ebrahimzadeh SA, Abedi V, Papathanasiou M, Labedi A, Schneider R, Lukas C, Tsiodras S, Tsivgoulis G, Krogias C
J Neuroimaging 2021 Mar;31(2):228-243. Epub 2021 Jan 9 doi: 10.1111/jon.12819. PMID: 33421032Free PMC Article

Recent systematic reviews

Central neuroinflammation in Covid-19: a systematic review of 182 cases with encephalitis, acute disseminated encephalomyelitis, and necrotizing encephalopathies.
Zamani R, Pouremamali R, Rezaei N
Rev Neurosci 2022 Jun 27;33(4):397-412. Epub 2021 Sep 17 doi: 10.1515/revneuro-2021-0082. PMID: 34536341

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