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COVID-19-Associated Pneumonia

MedGen UID:
1771437
•Concept ID:
C5419163
•
Disease or Syndrome
Synonym: SARS-CoV-2 -Associated Pneumonia

Definition

Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is characterized by the presence of ground glass opacities on CT scan images. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19-Associated Pneumonia

Professional guidelines

PubMed

The immunomodulatory properties of low-level ionizing radiation as a potential treatment for COVID-19's life-threatening symptoms.
Hussien SM
Eur J Med Res 2023 Feb 11;28(1):73. doi: 10.1186/s40001-023-00999-7. PMID: 36774511Free PMC Article
Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission.
Calvet J, Berenguer-Llergo A, Gay M, Massanella M, Domingo P, Llop M, Sánchez-Jiménez E, Arévalo M, Carrillo J, Albiñana N, Arauz-Garofalo G, Orellana C, Delgado JF, Serrano A, Llobell A, Graell E, García-Manrique M, Moreno M, Galisteo C, Casado E, Navarro N, Gómez A, Garcia-Cirera S, Rusiñol M, Costa E, Clotet B, Vilaseca M, Blanco J, Gratacós J
Sci Rep 2022 Jan 12;12(1):640. doi: 10.1038/s41598-021-04683-w. PMID: 35022497Free PMC Article
Tocilizumab treatment in severe COVID-19: a multicenter retrospective study with matched controls.
Mert A, Vahaboğlu H, Arslan F, Batirel A, Saraçoğlu KT, Bastug A, Çağatay A, Irmak İ, Dizman GT, Ertenli İ, Altunal LN, Sengel BE, Bayram M, Omma A, Amikishiyev S, Aypak A, Bes C, Bolukçu S, Içten S, Topeli A, Bektaş M, Arslan BY, Öztürk S, Çomoğlu Ş, Aydin S, Küçükşahin O, Içaçan OC, Ince B, Aghamuradov S, Mutlu MY, Şimşek F, Emre S, Ustun C, Ergen P, Aydin Ö, Koç MM, Sevindik ÖG, Odabaşı Z, Korten V, Bodur H, Güner R, Ünal S, Kocak M, Gül A
Rheumatol Int 2022 Mar;42(3):457-467. Epub 2021 Sep 13 doi: 10.1007/s00296-021-04965-6. PMID: 34515808Free PMC Article

Recent clinical studies

Etiology

COVID-19-associated Mucormycosis: A clinico-epidemiological study.
Chakravarty J, Gupta MK, Tilak R, Kumar R, Maurya RP, Kumar N, Aggarwal SK, S S, Sharma NK, Dhiman NK, Chaubey M, Singh V, Verma A, Banerjee T, Agrawal NK, Prasad RS
J Diabetes Complications 2022 Sep;36(9):108284. Epub 2022 Aug 13 doi: 10.1016/j.jdiacomp.2022.108284. PMID: 35987108Free PMC Article
Prevalence, Characteristics, and Outcomes of COVID-19-Associated Acute Myocarditis.
Ammirati E, Lupi L, Palazzini M, Hendren NS, Grodin JL, Cannistraci CV, Schmidt M, Hekimian G, Peretto G, Bochaton T, Hayek A, Piriou N, Leonardi S, Guida S, Turco A, Sala S, Uribarri A, Van de Heyning CM, Mapelli M, Campodonico J, Pedrotti P, Barrionuevo Sánchez MI, Ariza Sole A, Marini M, Matassini MV, Vourc'h M, Cannatà A, Bromage DI, Briguglia D, Salamanca J, Diez-Villanueva P, Lehtonen J, Huang F, Russel S, Soriano F, Turrini F, Cipriani M, Bramerio M, Di Pasquale M, Grosu A, Senni M, Farina D, Agostoni P, Rizzo S, De Gaspari M, Marzo F, Duran JM, Adler ED, Giannattasio C, Basso C, McDonagh T, Kerneis M, Combes A, Camici PG, de Lemos JA, Metra M
Circulation 2022 Apr 12;145(15):1123-1139. Epub 2022 Apr 11 doi: 10.1161/CIRCULATIONAHA.121.056817. PMID: 35404682Free PMC Article
Nailfold Videocapillaroscopy in Patients with COVID-19-associated Pneumonia in Intensive Care Units.
Karahan S, Aydin K, Cetinkaya A, Sirakaya HA
J Coll Physicians Surg Pak 2022 Apr;32(4):455-460. doi: 10.29271/jcpsp.2022.04.455. PMID: 35330517
Antiphospholipid antibodies in COVID-19-associated pneumonia patients in intensive care unit.
Karahan S, Erol K, Yuksel RC, Artan C, Celik I
Mod Rheumatol 2022 Jan 5;32(1):163-168. doi: 10.1080/14397595.2021.1892257. PMID: 33620009Free PMC Article
Tocilizumab use in COVID-19-associated pneumonia.
Okoh AK, Bishburg E, Grinberg S, Nagarakanti S
J Med Virol 2021 Feb;93(2):1023-1028. Epub 2020 Oct 5 doi: 10.1002/jmv.26471. PMID: 32860432

Diagnosis

COVID-19-associated Mucormycosis: A clinico-epidemiological study.
Chakravarty J, Gupta MK, Tilak R, Kumar R, Maurya RP, Kumar N, Aggarwal SK, S S, Sharma NK, Dhiman NK, Chaubey M, Singh V, Verma A, Banerjee T, Agrawal NK, Prasad RS
J Diabetes Complications 2022 Sep;36(9):108284. Epub 2022 Aug 13 doi: 10.1016/j.jdiacomp.2022.108284. PMID: 35987108Free PMC Article
Prevalence, Characteristics, and Outcomes of COVID-19-Associated Acute Myocarditis.
Ammirati E, Lupi L, Palazzini M, Hendren NS, Grodin JL, Cannistraci CV, Schmidt M, Hekimian G, Peretto G, Bochaton T, Hayek A, Piriou N, Leonardi S, Guida S, Turco A, Sala S, Uribarri A, Van de Heyning CM, Mapelli M, Campodonico J, Pedrotti P, Barrionuevo Sánchez MI, Ariza Sole A, Marini M, Matassini MV, Vourc'h M, Cannatà A, Bromage DI, Briguglia D, Salamanca J, Diez-Villanueva P, Lehtonen J, Huang F, Russel S, Soriano F, Turrini F, Cipriani M, Bramerio M, Di Pasquale M, Grosu A, Senni M, Farina D, Agostoni P, Rizzo S, De Gaspari M, Marzo F, Duran JM, Adler ED, Giannattasio C, Basso C, McDonagh T, Kerneis M, Combes A, Camici PG, de Lemos JA, Metra M
Circulation 2022 Apr 12;145(15):1123-1139. Epub 2022 Apr 11 doi: 10.1161/CIRCULATIONAHA.121.056817. PMID: 35404682Free PMC Article
Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?
Liu JM, Chi J
Exp Biol Med (Maywood) 2022 Feb;247(4):330-337. Epub 2022 Jan 22 doi: 10.1177/15353702211068840. PMID: 35068219Free PMC Article
Antiphospholipid antibodies in COVID-19-associated pneumonia patients in intensive care unit.
Karahan S, Erol K, Yuksel RC, Artan C, Celik I
Mod Rheumatol 2022 Jan 5;32(1):163-168. doi: 10.1080/14397595.2021.1892257. PMID: 33620009Free PMC Article
COVID-19 Associated Pneumonia: A review of chest radiograph and computed tomography findings.
Al-Umairi RS, Al-Kalbani J, Al-Tai S, Al-Abri A, Al-Kindi F, Kamona A
Sultan Qaboos Univ Med J 2021 Feb;21(1):e4-e11. Epub 2021 Mar 15 doi: 10.18295/squmj.2021.21.01.002. PMID: 33777418Free PMC Article

Therapy

Therapeutic Effectiveness of Interferon-α2b against COVID-19 with Community-Acquired Pneumonia: The Ukrainian Experience.
Kamyshnyi A, Koval H, Kobevko O, Buchynskyi M, Oksenych V, Kainov D, Lyubomirskaya K, Kamyshna I, Potters G, Moshynets O
Int J Mol Sci 2023 Apr 7;24(8) doi: 10.3390/ijms24086887. PMID: 37108051Free PMC Article
COVID-19-associated Mucormycosis: A clinico-epidemiological study.
Chakravarty J, Gupta MK, Tilak R, Kumar R, Maurya RP, Kumar N, Aggarwal SK, S S, Sharma NK, Dhiman NK, Chaubey M, Singh V, Verma A, Banerjee T, Agrawal NK, Prasad RS
J Diabetes Complications 2022 Sep;36(9):108284. Epub 2022 Aug 13 doi: 10.1016/j.jdiacomp.2022.108284. PMID: 35987108Free PMC Article
Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?
Liu JM, Chi J
Exp Biol Med (Maywood) 2022 Feb;247(4):330-337. Epub 2022 Jan 22 doi: 10.1177/15353702211068840. PMID: 35068219Free PMC Article
Tocilizumab use in COVID-19-associated pneumonia.
Okoh AK, Bishburg E, Grinberg S, Nagarakanti S
J Med Virol 2021 Feb;93(2):1023-1028. Epub 2020 Oct 5 doi: 10.1002/jmv.26471. PMID: 32860432
Association Between Hypoxemia and Mortality in Patients With COVID-19.
Xie J, Covassin N, Fan Z, Singh P, Gao W, Li G, Kara T, Somers VK
Mayo Clin Proc 2020 Jun;95(6):1138-1147. Epub 2020 Apr 11 doi: 10.1016/j.mayocp.2020.04.006. PMID: 32376101Free PMC Article

Prognosis

Factors Associated with Mortality in Patients with COVID-19 Receiving Prolonged Ventilatory Support.
Bergman ZR, Tignanelli CJ, Gould R, Pendleton KM, Chipman JG, Lusczek E, Beilman G
Surg Infect (Larchmt) 2022 Dec;23(10):893-901. Epub 2022 Nov 16 doi: 10.1089/sur.2022.195. PMID: 36383156Free PMC Article
Characteristics of COVID-19 Pneumonia Survivors With Resting Normoxemia and Exercise-Induced Desaturation.
Vitacca M, Paneroni M, Brunetti G, Carlucci A, Balbi B, Spanevello A, Ambrosino N
Respir Care 2021 Nov;66(11):1657-1664. Epub 2021 Aug 24 doi: 10.4187/respcare.09029. PMID: 34429351
COVID-19 and Immunological Dysregulation: Can Autoantibodies be Useful?
Pascolini S, Vannini A, Deleonardi G, Ciordinik M, Sensoli A, Carletti I, Veronesi L, Ricci C, Pronesti A, Mazzanti L, Grondona A, Silvestri T, Zanuso S, Mazzolini M, Lalanne C, Quarneti C, Fusconi M, Giostra F, Granito A, Muratori L, Lenzi M, Muratori P
Clin Transl Sci 2021 Mar;14(2):502-508. Epub 2021 Jan 20 doi: 10.1111/cts.12908. PMID: 32989903Free PMC Article
Tocilizumab use in COVID-19-associated pneumonia.
Okoh AK, Bishburg E, Grinberg S, Nagarakanti S
J Med Virol 2021 Feb;93(2):1023-1028. Epub 2020 Oct 5 doi: 10.1002/jmv.26471. PMID: 32860432
Association Between Hypoxemia and Mortality in Patients With COVID-19.
Xie J, Covassin N, Fan Z, Singh P, Gao W, Li G, Kara T, Somers VK
Mayo Clin Proc 2020 Jun;95(6):1138-1147. Epub 2020 Apr 11 doi: 10.1016/j.mayocp.2020.04.006. PMID: 32376101Free PMC Article

Clinical prediction guides

COVID-19-associated Mucormycosis: A clinico-epidemiological study.
Chakravarty J, Gupta MK, Tilak R, Kumar R, Maurya RP, Kumar N, Aggarwal SK, S S, Sharma NK, Dhiman NK, Chaubey M, Singh V, Verma A, Banerjee T, Agrawal NK, Prasad RS
J Diabetes Complications 2022 Sep;36(9):108284. Epub 2022 Aug 13 doi: 10.1016/j.jdiacomp.2022.108284. PMID: 35987108Free PMC Article
Antiphospholipid antibodies in COVID-19-associated pneumonia patients in intensive care unit.
Karahan S, Erol K, Yuksel RC, Artan C, Celik I
Mod Rheumatol 2022 Jan 5;32(1):163-168. doi: 10.1080/14397595.2021.1892257. PMID: 33620009Free PMC Article
Characteristics of COVID-19 Pneumonia Survivors With Resting Normoxemia and Exercise-Induced Desaturation.
Vitacca M, Paneroni M, Brunetti G, Carlucci A, Balbi B, Spanevello A, Ambrosino N
Respir Care 2021 Nov;66(11):1657-1664. Epub 2021 Aug 24 doi: 10.4187/respcare.09029. PMID: 34429351
Tocilizumab use in COVID-19-associated pneumonia.
Okoh AK, Bishburg E, Grinberg S, Nagarakanti S
J Med Virol 2021 Feb;93(2):1023-1028. Epub 2020 Oct 5 doi: 10.1002/jmv.26471. PMID: 32860432
Association Between Hypoxemia and Mortality in Patients With COVID-19.
Xie J, Covassin N, Fan Z, Singh P, Gao W, Li G, Kara T, Somers VK
Mayo Clin Proc 2020 Jun;95(6):1138-1147. Epub 2020 Apr 11 doi: 10.1016/j.mayocp.2020.04.006. PMID: 32376101Free PMC Article

Recent systematic reviews

Research Status of the Safety and Efficacy of Mesenchymal Stem Cells in the Treatment of COVID-19-Related Pneumonia: A Systematic Review and Meta-Analysis.
Wang J, Shi P, Chen D, Wang S, Wang P, Feng X, Zhang L
Stem Cells Dev 2021 Oct 1;30(19):947-969. doi: 10.1089/scd.2021.0179. PMID: 34416823

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