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Glomerular basement membranes powdery deposit

MedGen UID:
1778407
•Concept ID:
C5539637
•
Finding
Synonym: Glomerular basement membranes with powdery deposit
 
HPO: HP:0033487

Definition

Punctate electron-dense material typically in a band-like distribution along the lamina rara interna and within tubular basement membranes within the subendothelial aspect of the glomerular basement membrane. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlomerular basement membranes powdery deposit

Recent clinical studies

Diagnosis

Light chain deposition disease masquerading as smoking-associated nodular glomerulosclerosis with deposits identified by electron microscopy only.
Alom MS, Grewal R, Passero FC, Goldman B, Choung HYG
CEN Case Rep 2022 Nov;11(4):448-452. Epub 2022 Mar 22 doi: 10.1007/s13730-022-00698-y. PMID: 35316527Free PMC Article
Light chain deposition disease involving kidney and liver in a patient with IgD myeloma.
Tsushima T, Suzuki T, Terao T, Miura D, Narita K, Takeuchi M, Shimuzu A, Matsue K
BMC Nephrol 2021 Jan 23;22(1):40. doi: 10.1186/s12882-021-02246-9. PMID: 33485303Free PMC Article
Polyclonal immunoglobulin G deposition on the tubular basement membrane in a diabetic nephropathy: A case report.
Watanabe H, Takeuchi Y, Taniuchi S, Sato H, Nakamura Y, Sasano H, Joh K
Pathol Int 2020 Jul;70(7):463-469. Epub 2020 May 17 doi: 10.1111/pin.12940. PMID: 32419249

Clinical prediction guides

Polyclonal immunoglobulin G deposition on the tubular basement membrane in a diabetic nephropathy: A case report.
Watanabe H, Takeuchi Y, Taniuchi S, Sato H, Nakamura Y, Sasano H, Joh K
Pathol Int 2020 Jul;70(7):463-469. Epub 2020 May 17 doi: 10.1111/pin.12940. PMID: 32419249

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