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Lower extremity hypokinesia

MedGen UID:
1779328
•Concept ID:
C5539575
•
Finding
Synonym: Hypokinesia of the lower extremities
 
HPO: HP:0033414

Definition

Abnormally diminished movement of the lower extremities. In contrast to paralysis, hypokinesia is not characterized by a lack of motor strength, but rather by a poverty of movement. The typical habitual movements (e.g., folding the arms, crossing the legs) are reduced in frequency. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLower extremity hypokinesia

Recent clinical studies

Etiology

Progressive Resistance Training Improves Bradykinesia, Motor Symptoms and Functional Performance in Patients with Parkinson's Disease.
Vieira de Moraes Filho A, Chaves SN, Martins WR, Tolentino GP, de Cássia Pereira Pinto Homem R, Landim de Farias G, Fischer BL, Oliveira JA, Pereira SKA, Vidal SE, Mota MR, Moreno Lima R, Jacó de Oliveira R
Clin Interv Aging 2020;15:87-95. Epub 2020 Jan 23 doi: 10.2147/CIA.S231359. PMID: 32158202Free PMC Article
Takotsubo syndrome with pulmonary embolism: a case report and literature review.
Jin Q, Luo Q, Zhao Z, Zhao Q, Yu X, Yan L, Gao L, Liu Z
BMC Cardiovasc Disord 2018 Dec 10;18(1):229. doi: 10.1186/s12872-018-0953-7. PMID: 30526522Free PMC Article
Interlimb coordination is impaired during walking in persons with Parkinson's disease.
Roemmich RT, Field AM, Elrod JM, Stegemöller EL, Okun MS, Hass CJ
Clin Biomech (Bristol, Avon) 2013 Jan;28(1):93-7. Epub 2012 Oct 10 doi: 10.1016/j.clinbiomech.2012.09.005. PMID: 23062816Free PMC Article
Utilization of magnesium during hypokinesia and magnesium supplementation in healthy subjects.
Zorbas YG, Kakuris KK, Federenko YF, Deogenov VA
Nutrition 2010 Nov-Dec;26(11-12):1134-8. Epub 2010 Apr 3 doi: 10.1016/j.nut.2010.01.013. PMID: 20363596
Circulatory hypokinesis and functional electric stimulation during standing in persons with spinal cord injury.
Faghri PD, Yount JP, Pesce WJ, Seetharama S, Votto JJ
Arch Phys Med Rehabil 2001 Nov;82(11):1587-95. doi: 10.1053/apmr.2001.25984. PMID: 11689980

Diagnosis

Progressive Resistance Training Improves Bradykinesia, Motor Symptoms and Functional Performance in Patients with Parkinson's Disease.
Vieira de Moraes Filho A, Chaves SN, Martins WR, Tolentino GP, de Cássia Pereira Pinto Homem R, Landim de Farias G, Fischer BL, Oliveira JA, Pereira SKA, Vidal SE, Mota MR, Moreno Lima R, Jacó de Oliveira R
Clin Interv Aging 2020;15:87-95. Epub 2020 Jan 23 doi: 10.2147/CIA.S231359. PMID: 32158202Free PMC Article
Takotsubo syndrome with pulmonary embolism: a case report and literature review.
Jin Q, Luo Q, Zhao Z, Zhao Q, Yu X, Yan L, Gao L, Liu Z
BMC Cardiovasc Disord 2018 Dec 10;18(1):229. doi: 10.1186/s12872-018-0953-7. PMID: 30526522Free PMC Article
A little trouble getting started: Initial slowness in Parkinson's disease step negotiation.
Stone AE, Skinner JW, Lee HK, Hass CJ
Gait Posture 2017 Sep;57:97-101. Epub 2017 May 31 doi: 10.1016/j.gaitpost.2017.05.030. PMID: 28582720
Reliability and validity of an instrument for the assessment of bradykinesia.
Mentzel TQ, Lieverse R, Levens A, Mentzel CL, Tenback DE, Bakker PR, Daanen HAM, van Harten PN
Psychiatry Res 2016 Apr 30;238:189-195. Epub 2016 Feb 17 doi: 10.1016/j.psychres.2016.02.011. PMID: 27086232
Interlimb coordination is impaired during walking in persons with Parkinson's disease.
Roemmich RT, Field AM, Elrod JM, Stegemöller EL, Okun MS, Hass CJ
Clin Biomech (Bristol, Avon) 2013 Jan;28(1):93-7. Epub 2012 Oct 10 doi: 10.1016/j.clinbiomech.2012.09.005. PMID: 23062816Free PMC Article

Therapy

Effects of rhythmic auditory stimulation on upper-limb movements in patients with Parkinson's disease.
Fan W, Li J, Wei W, Xiao SH, Liao ZJ, Wang SM, Fong KNK
Parkinsonism Relat Disord 2022 Aug;101:27-30. Epub 2022 Jun 23 doi: 10.1016/j.parkreldis.2022.06.020. PMID: 35763906
Progressive Resistance Training Improves Bradykinesia, Motor Symptoms and Functional Performance in Patients with Parkinson's Disease.
Vieira de Moraes Filho A, Chaves SN, Martins WR, Tolentino GP, de Cássia Pereira Pinto Homem R, Landim de Farias G, Fischer BL, Oliveira JA, Pereira SKA, Vidal SE, Mota MR, Moreno Lima R, Jacó de Oliveira R
Clin Interv Aging 2020;15:87-95. Epub 2020 Jan 23 doi: 10.2147/CIA.S231359. PMID: 32158202Free PMC Article
Takotsubo syndrome with pulmonary embolism: a case report and literature review.
Jin Q, Luo Q, Zhao Z, Zhao Q, Yu X, Yan L, Gao L, Liu Z
BMC Cardiovasc Disord 2018 Dec 10;18(1):229. doi: 10.1186/s12872-018-0953-7. PMID: 30526522Free PMC Article
Automated motion sensor quantification of gait and lower extremity bradykinesia.
Heldman DA, Filipkowski DE, Riley DE, Whitney CM, Walter BL, Gunzler SA, Giuffrida JP, Mera TO
Annu Int Conf IEEE Eng Med Biol Soc 2012;2012:1956-9. doi: 10.1109/EMBC.2012.6346338. PMID: 23366299Free PMC Article
Utilization of magnesium during hypokinesia and magnesium supplementation in healthy subjects.
Zorbas YG, Kakuris KK, Federenko YF, Deogenov VA
Nutrition 2010 Nov-Dec;26(11-12):1134-8. Epub 2010 Apr 3 doi: 10.1016/j.nut.2010.01.013. PMID: 20363596

Prognosis

Motion Sensor-Based Assessment of Parkinson's Disease Motor Symptoms During Leg Agility Tests: Results From Levodopa Challenge.
Aghanavesi S, Bergquist F, Nyholm D, Senek M, Memedi M
IEEE J Biomed Health Inform 2020 Jan;24(1):111-119. Epub 2019 Feb 8 doi: 10.1109/JBHI.2019.2898332. PMID: 30763248

Clinical prediction guides

Effects of rhythmic auditory stimulation on upper-limb movements in patients with Parkinson's disease.
Fan W, Li J, Wei W, Xiao SH, Liao ZJ, Wang SM, Fong KNK
Parkinsonism Relat Disord 2022 Aug;101:27-30. Epub 2022 Jun 23 doi: 10.1016/j.parkreldis.2022.06.020. PMID: 35763906
Characterization and localization of upper and lower extremity motor improvements in STN DBS for Parkinson's disease.
Askari A, Zhu BJ, Lyu X, Chou KL, Patil PG
Parkinsonism Relat Disord 2022 Jan;94:84-88. Epub 2021 Dec 2 doi: 10.1016/j.parkreldis.2021.11.036. PMID: 34896928
Reliability and validity of an instrument for the assessment of bradykinesia.
Mentzel TQ, Lieverse R, Levens A, Mentzel CL, Tenback DE, Bakker PR, Daanen HAM, van Harten PN
Psychiatry Res 2016 Apr 30;238:189-195. Epub 2016 Feb 17 doi: 10.1016/j.psychres.2016.02.011. PMID: 27086232
Interlimb coordination is impaired during walking in persons with Parkinson's disease.
Roemmich RT, Field AM, Elrod JM, Stegemöller EL, Okun MS, Hass CJ
Clin Biomech (Bristol, Avon) 2013 Jan;28(1):93-7. Epub 2012 Oct 10 doi: 10.1016/j.clinbiomech.2012.09.005. PMID: 23062816Free PMC Article
Analysis of lower limb bradykinesia in Parkinson's disease patients.
Kim JW, Kwon Y, Kim YM, Chung HY, Eom GM, Jun JH, Lee JW, Koh SB, Park BK, Kwon DK
Geriatr Gerontol Int 2012 Apr;12(2):257-64. Epub 2011 Oct 17 doi: 10.1111/j.1447-0594.2011.00761.x. PMID: 21999184

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