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EEG with centrotemporal epileptiform discharges

MedGen UID:
1782134
•Concept ID:
C5539780
•
Finding
HPO: HP:0033721

Definition

Focal epileptiform EEG discharges recorded in the centrotemporal region. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEEG with centrotemporal epileptiform discharges

Professional guidelines

PubMed

Levetiracetam versus carbamazepine in treatment of rolandic epilepsy.
Asadi-Pooya AA, Forouzesh M, Eidi H, Mirzaghafour SE
Epilepsy Behav 2019 May;94:1-8. Epub 2019 Mar 15 doi: 10.1016/j.yebeh.2019.02.009. PMID: 30884401
Analysis of EEG patterns and genotypes in patients with Angelman syndrome.
Vendrame M, Loddenkemper T, Zarowski M, Gregas M, Shuhaiber H, Sarco DP, Morales A, Nespeca M, Sharpe C, Haas K, Barnes G, Glaze D, Kothare SV
Epilepsy Behav 2012 Mar;23(3):261-5. Epub 2012 Feb 16 doi: 10.1016/j.yebeh.2011.11.027. PMID: 22341959

Recent clinical studies

Etiology

Spike height improves prediction of future seizure risk.
Chinappen DM, Xiao G, Jing J, Spencer ER, Eden UT, Kramer MA, Westover MB, Chu CJ
Clin Neurophysiol 2023 Jun;150:49-55. Epub 2023 Mar 21 doi: 10.1016/j.clinph.2023.02.180. PMID: 37002980Free PMC Article
Cortical morphology, epileptiform discharges, and neuropsychological performance in BECTS.
Fujiwara H, Tenney J, Kadis DS, Byars A, Altaye M, Spencer C, Glauser T, Vannest J
Acta Neurol Scand 2018 Nov;138(5):432-440. Epub 2018 Jul 10 doi: 10.1111/ane.12997. PMID: 29989147Free PMC Article
Prevalence of epileptiform discharges in healthy 11- and 12-year-old children.
Grant AC, Chau L, Arya K, Schneider M
Epilepsy Behav 2016 Sep;62:53-6. Epub 2016 Jul 21 doi: 10.1016/j.yebeh.2016.06.020. PMID: 27450305Free PMC Article
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Rolandic discharges: clinico-neurophysiological correlation.
Medeiros LL, Yasuda C, Schmutzler KM, Guerreiro MM
Clin Neurophysiol 2010 Oct;121(10):1740-3. Epub 2010 Jul 31 doi: 10.1016/j.clinph.2010.03.050. PMID: 20674483

Diagnosis

Spike height improves prediction of future seizure risk.
Chinappen DM, Xiao G, Jing J, Spencer ER, Eden UT, Kramer MA, Westover MB, Chu CJ
Clin Neurophysiol 2023 Jun;150:49-55. Epub 2023 Mar 21 doi: 10.1016/j.clinph.2023.02.180. PMID: 37002980Free PMC Article
Deep Learning-Based Detection of Epileptiform Discharges for Self-Limited Epilepsy With Centrotemporal Spikes.
Jeon Y, Chung YG, Joo T, Kim H, Hwang H, Kim KJ
IEEE Trans Neural Syst Rehabil Eng 2022;30:2939-2949. Epub 2022 Oct 27 doi: 10.1109/TNSRE.2022.3215526. PMID: 36260578
Electroencephalography in clinical epilepsy research.
Herman ST, Takeoka M, Hughes JR, Drislane FW
Epilepsy Behav 2011 Sep;22(1):126-33. Epub 2011 Aug 6 doi: 10.1016/j.yebeh.2011.06.009. PMID: 21824821
The EEG findings in extratemporal seizures.
Westmoreland BF
Epilepsia 1998;39 Suppl 4:S1-8. doi: 10.1111/j.1528-1157.1998.tb05121.x. PMID: 9637588
Epileptiform electroencephalographic patterns.
Westmoreland BF
Mayo Clin Proc 1996 May;71(5):501-11. doi: 10.4065/71.5.501. PMID: 8628033

Therapy

Clinical and electroencephalographic features of benign childhood epilepsy with centrotemporal spikes comorbidity with attention-deficit hyperactivity disorder in Southwest China.
Huang C, Hu W, Tan G, Xu Y, Liu L
Epilepsy Behav 2020 Oct;111:107240. Epub 2020 Jun 27 doi: 10.1016/j.yebeh.2020.107240. PMID: 32603807
Levetiracetam versus carbamazepine in treatment of rolandic epilepsy.
Asadi-Pooya AA, Forouzesh M, Eidi H, Mirzaghafour SE
Epilepsy Behav 2019 May;94:1-8. Epub 2019 Mar 15 doi: 10.1016/j.yebeh.2019.02.009. PMID: 30884401
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Benign epilepsy of childhood with centrotemporal spikes (BECTS): to treat or not to treat, that is the question.
Hughes JR
Epilepsy Behav 2010 Nov;19(3):197-203. Epub 2010 Aug 24 doi: 10.1016/j.yebeh.2010.07.018. PMID: 20797913
Cognitive and behavioral effects of nocturnal epileptiform discharges in children with benign childhood epilepsy with centrotemporal spikes.
Nicolai J, Aldenkamp AP, Arends J, Weber JW, Vles JS
Epilepsy Behav 2006 Feb;8(1):56-70. Epub 2005 Nov 2 doi: 10.1016/j.yebeh.2005.08.016. PMID: 16263335

Prognosis

Spike height improves prediction of future seizure risk.
Chinappen DM, Xiao G, Jing J, Spencer ER, Eden UT, Kramer MA, Westover MB, Chu CJ
Clin Neurophysiol 2023 Jun;150:49-55. Epub 2023 Mar 21 doi: 10.1016/j.clinph.2023.02.180. PMID: 37002980Free PMC Article
Enhancement and bilateral synchronization of ripples in atypical benign epilepsy of childhood with centrotemporal spikes.
Ikemoto S, Hamano SI, Yokota S, Koichihara R, Hirata Y, Matsuura R
Clin Neurophysiol 2018 Sep;129(9):1920-1925. Epub 2018 Jul 6 doi: 10.1016/j.clinph.2018.06.023. PMID: 30005220
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Analysis of EEG patterns and genotypes in patients with Angelman syndrome.
Vendrame M, Loddenkemper T, Zarowski M, Gregas M, Shuhaiber H, Sarco DP, Morales A, Nespeca M, Sharpe C, Haas K, Barnes G, Glaze D, Kothare SV
Epilepsy Behav 2012 Mar;23(3):261-5. Epub 2012 Feb 16 doi: 10.1016/j.yebeh.2011.11.027. PMID: 22341959
Idiopathic epileptic syndromes and cognition.
Hommet C, Sauerwein HC, De Toffol B, Lassonde M
Neurosci Biobehav Rev 2006;30(1):85-96. Epub 2005 Aug 24 doi: 10.1016/j.neubiorev.2005.06.004. PMID: 16120462

Clinical prediction guides

Spike height improves prediction of future seizure risk.
Chinappen DM, Xiao G, Jing J, Spencer ER, Eden UT, Kramer MA, Westover MB, Chu CJ
Clin Neurophysiol 2023 Jun;150:49-55. Epub 2023 Mar 21 doi: 10.1016/j.clinph.2023.02.180. PMID: 37002980Free PMC Article
Deep Learning-Based Detection of Epileptiform Discharges for Self-Limited Epilepsy With Centrotemporal Spikes.
Jeon Y, Chung YG, Joo T, Kim H, Hwang H, Kim KJ
IEEE Trans Neural Syst Rehabil Eng 2022;30:2939-2949. Epub 2022 Oct 27 doi: 10.1109/TNSRE.2022.3215526. PMID: 36260578
Cortical morphology, epileptiform discharges, and neuropsychological performance in BECTS.
Fujiwara H, Tenney J, Kadis DS, Byars A, Altaye M, Spencer C, Glauser T, Vannest J
Acta Neurol Scand 2018 Nov;138(5):432-440. Epub 2018 Jul 10 doi: 10.1111/ane.12997. PMID: 29989147Free PMC Article
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Idiopathic epileptic syndromes and cognition.
Hommet C, Sauerwein HC, De Toffol B, Lassonde M
Neurosci Biobehav Rev 2006;30(1):85-96. Epub 2005 Aug 24 doi: 10.1016/j.neubiorev.2005.06.004. PMID: 16120462

Recent systematic reviews

Prognostic interictal electroencephalographic biomarkers and models to assess antiseizure medication efficacy for clinical practice: A scoping review.
Reynolds A, Vranic-Peters M, Lai A, Grayden DB, Cook MJ, Peterson A
Epilepsia 2023 May;64(5):1125-1174. Epub 2023 Mar 16 doi: 10.1111/epi.17548. PMID: 36790369
Levetiracetam versus carbamazepine in treatment of rolandic epilepsy.
Asadi-Pooya AA, Forouzesh M, Eidi H, Mirzaghafour SE
Epilepsy Behav 2019 May;94:1-8. Epub 2019 Mar 15 doi: 10.1016/j.yebeh.2019.02.009. PMID: 30884401

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