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Anti-transglutaminase 6 antibody

MedGen UID:
1784435
•Concept ID:
C5539875
•
Laboratory or Test Result
HPO: HP:4000026

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against transglutaminase 6. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-transglutaminase 6 antibody

Professional guidelines

PubMed

Comparison of Clinical, Biochemical and Histological Features between Adult Celiac Patients with High and Low Anti-Transglutaminase IgA Titer at Diagnosis and Follow-Up.
Galli G, Carabotti M, Conti L, Scalamonti S, Annibale B, Lahner E
Nutrients 2023 Apr 29;15(9) doi: 10.3390/nu15092151. PMID: 37432272Free PMC Article
HLA-DQ genotype and biochemical characterization of anti-transglutaminase 2 antibodies in patients with type 1 diabetes mellitus in Taiwan.
Lee YJ, Ting WH, Yang YW, Lin CJ, Hsieh YT, Huang CY, Lo FS, Chu CC, Lin CL, Lin WS, Lai TS
FASEB J 2020 Jun;34(6):8459-8474. Epub 2020 May 3 doi: 10.1096/fj.202000269R. PMID: 32362042
Detection of Celiac disease in primary care: a multicenter case-finding study in North America.
Catassi C, Kryszak D, Louis-Jacques O, Duerksen DR, Hill I, Crowe SE, Brown AR, Procaccini NJ, Wonderly BA, Hartley P, Moreci J, Bennett N, Horvath K, Burk M, Fasano A
Am J Gastroenterol 2007 Jul;102(7):1454-60. Epub 2007 Mar 13 doi: 10.1111/j.1572-0241.2007.01173.x. PMID: 17355413

Recent systematic reviews

Diagnostic Accuracy of IgA Anti-Transglutaminase Assessed by Chemiluminescence: A Systematic Review and Meta-Analysis.
Pjetraj D, Pulvirenti A, Moretti M, Gatti S, Catassi GN, Catassi C, Lionetti E
Nutrients 2024 Jul 26;16(15) doi: 10.3390/nu16152427. PMID: 39125307Free PMC Article
The Prevalence of the Celiac Disease in Patients with Dyspepsia: A Systematic Review and Meta-Analysis.
Singh AD, Ellias S, Singh P, Ahuja V, Makharia GK
Dig Dis Sci 2022 Jul;67(7):3067-3079. Epub 2021 Jul 15 doi: 10.1007/s10620-021-07142-8. PMID: 34268659
Diagnostic Accuracy of IgA Anti-Transglutaminase and IgG Anti-Deamidated Gliadin for Diagnosis of Celiac Disease in Children under Two Years of Age: A Systematic Review and Meta-Analysis.
Catassi GN, Pulvirenti A, Monachesi C, Catassi C, Lionetti E
Nutrients 2021 Dec 21;14(1) doi: 10.3390/nu14010007. PMID: 35010880Free PMC Article
Systematic Review and Meta-Analysis of Prevalence of Coeliac Disease in Women with Infertility.
Castaño M, Gómez-Gordo R, Cuevas D, Núñez C
Nutrients 2019 Aug 20;11(8) doi: 10.3390/nu11081950. PMID: 31434238Free PMC Article
Celiac disease in type 1 diabetes mellitus in the Kingdom of Saudi Arabia. Characterization and meta-analysis.
Safi MA
Saudi Med J 2019 Jul;40(7):647-656. doi: 10.15537/smj.2019.7.24293. PMID: 31287124Free PMC Article

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