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Glomerular basement membrane lucencies

MedGen UID:: 1785257
•Concept ID:: C5539483
•: Finding

HPO:	HP:0033287

Definition

Lucent zones within the glomerular basement membranes. May reflect remote/resolved deposits. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVGlomerular basement membrane lucencies

Abnormal nephron morphology
- Abnormal renal corpuscle morphology
  - Abnormal renal glomerulus morphology
    - Glomerular deposits
      - Glomerular subepithelial deposits
        Abnormal glomerular basement membrane morphology
        Glomerular basement membrane lucencies

Recent clinical studies

Etiology

Early identification of transplant glomerulopathy in pediatric kidney transplant biopsies: A single-center experience with electron microscopy analysis.

Grodsky JD, Craver RD, Ashoor IF
Pediatr Transplant 2019 Aug;23(5):e13459. Epub 2019 May 7 doi: 10.1111/petr.13459. PMID: 31062922

Diagnosis

Early identification of transplant glomerulopathy in pediatric kidney transplant biopsies: A single-center experience with electron microscopy analysis.

Grodsky JD, Craver RD, Ashoor IF
Pediatr Transplant 2019 Aug;23(5):e13459. Epub 2019 May 7 doi: 10.1111/petr.13459. PMID: 31062922

Histopathology, ultrastructure, and clinical phenotypes in thin glomerular basement membrane disease variants.

Liapis H, Gökden N, Hmiel P, Miner JH
Hum Pathol 2002 Aug;33(8):836-45. doi: 10.1053/hupa.2002.125374. PMID: 12203217

Prognosis

Early identification of transplant glomerulopathy in pediatric kidney transplant biopsies: A single-center experience with electron microscopy analysis.

Grodsky JD, Craver RD, Ashoor IF
Pediatr Transplant 2019 Aug;23(5):e13459. Epub 2019 May 7 doi: 10.1111/petr.13459. PMID: 31062922

Supplemental Content

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Clinical resources

ClinicalTrials.gov

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MedlinePlus

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Glomerular basement membrane lucencies
Glomerular basement membrane lucencies

MedGen
C34473 Yuji Kohara unpublished cDNA:Strain N2 hermaphrodite embryo Caenorhabditi...
C34473 Yuji Kohara unpublished cDNA:Strain N2 hermaphrodite embryo Caenorhabditis elegans cDNA clone yk402c8 3', mRNA sequence
gi|2370614|gnl|dbEST|1241880|dbj|C3 1|

Nucleotide

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