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Glomerular subendothelial widening

MedGen UID:
1785616
Concept ID:
C5539485
Finding
HPO: HP:0033290

Definition

Expansion of the space between the glomerular endothelium and lamina densa by electron-lucent material. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlomerular subendothelial widening

Professional guidelines

PubMed

Seymour AE, Canny A, Spargo BH
Ultrastruct Pathol 1983 Mar-Apr;4(2-3):123-43. doi: 10.3109/01913128309140784. PMID: 6879730

Recent clinical studies

Etiology

Shimizu M, Furuichi K, Toyama T, Yamanouchi M, Hoshino J, Kitajima S, Hara A, Iwata Y, Sakai N, Yuzawa Y, Kitamura H, Sato H, Shibagaki Y, Suzuki Y, Uesugi N, Ueda Y, Kohagura K, Samejima K, Tsuruya K, Nishi S, Nishino T, Makino H, Matsuo S, Ubara Y, Yokoyama H, Wada T; Research Group of Diabetic Nephropathy, the Ministry of Health, Labour and Welfare, and the Japan Agency for Medical Research and Development
J Diabetes Investig 2023 Nov;14(11):1268-1278. Epub 2023 Jul 22 doi: 10.1111/jdi.14059. PMID: 37483063Free PMC Article
Chen X, Zhang X, Wang Y, Wang S, Zhao M
J Nephrol 2023 Dec;36(9):2477-2490. Epub 2023 Apr 27 doi: 10.1007/s40620-023-01644-6. PMID: 37103770
Yüksel S, Işık Gönül İ, Canpolat N, Gökçe İ, Özlü SG, Özçakar ZB, Ozaltin F, Söylemezoğlu O
Pediatr Dev Pathol 2020 Sep-Oct;23(5):362-371. Epub 2020 May 14 doi: 10.1177/1093526620925947. PMID: 32406813
Taneda S, Honda K, Ohno M, Uchida K, Nitta K, Oda H
Virchows Arch 2015 Oct;467(4):449-58. Epub 2015 Aug 13 doi: 10.1007/s00428-015-1821-9. PMID: 26266776Free PMC Article
Suri DL, Tomlanovich SJ, Olson JL, Meyer TW
Am J Kidney Dis 2000 Apr;35(4):674-80. doi: 10.1016/s0272-6386(00)70015-1. PMID: 10739789

Diagnosis

Chen X, Zhang X, Wang Y, Wang S, Zhao M
J Nephrol 2023 Dec;36(9):2477-2490. Epub 2023 Apr 27 doi: 10.1007/s40620-023-01644-6. PMID: 37103770
Yüksel S, Işık Gönül İ, Canpolat N, Gökçe İ, Özlü SG, Özçakar ZB, Ozaltin F, Söylemezoğlu O
Pediatr Dev Pathol 2020 Sep-Oct;23(5):362-371. Epub 2020 May 14 doi: 10.1177/1093526620925947. PMID: 32406813
Imai C, Kakihara T, Iwabuchi H, Tanaka A, Furukawa T, Uchiyama M
Pediatr Nephrol 2003 Apr;18(4):399-402. Epub 2003 Mar 21 doi: 10.1007/s00467-003-1081-9. PMID: 12700971
Tada T, Ohara A, Nagai Y, Otani M, Ger YC, Kawamura S
Nihon Jinzo Gakkai Shi 1995 Feb;37(2):145-50. PMID: 7752507
Cohen EP, Lawton CA, Moulder JE, Becker CG, Ash RC
Nephron 1993;64(4):626-35. doi: 10.1159/000187412. PMID: 8366991

Therapy

Arai T, Oguchi H, Shinoda K, Sakurabayashi K, Mikami T, Itabashi Y, Sakai K
Nephron 2020;144 Suppl 1(Suppl 1):18-27. Epub 2020 Dec 2 doi: 10.1159/000512143. PMID: 33264791Free PMC Article
Salvatore SP, Troxell ML, Hecox D, Sperling KR, Seshan SV
Am J Nephrol 2015;41(1):66-72. Epub 2015 Feb 5 doi: 10.1159/000371727. PMID: 25659349
Sreedharanunni S, Joshi K, Duggal R, Nada R, Minz M, Sakhuja V
Transpl Int 2014 Aug;27(8):784-92. Epub 2014 May 24 doi: 10.1111/tri.12331. PMID: 24684170
Imai C, Kakihara T, Iwabuchi H, Tanaka A, Furukawa T, Uchiyama M
Pediatr Nephrol 2003 Apr;18(4):399-402. Epub 2003 Mar 21 doi: 10.1007/s00467-003-1081-9. PMID: 12700971
Cohen EP, Lawton CA, Moulder JE, Becker CG, Ash RC
Nephron 1993;64(4):626-35. doi: 10.1159/000187412. PMID: 8366991

Prognosis

Yüksel S, Işık Gönül İ, Canpolat N, Gökçe İ, Özlü SG, Özçakar ZB, Ozaltin F, Söylemezoğlu O
Pediatr Dev Pathol 2020 Sep-Oct;23(5):362-371. Epub 2020 May 14 doi: 10.1177/1093526620925947. PMID: 32406813
Taneda S, Honda K, Ohno M, Uchida K, Nitta K, Oda H
Virchows Arch 2015 Oct;467(4):449-58. Epub 2015 Aug 13 doi: 10.1007/s00428-015-1821-9. PMID: 26266776Free PMC Article
Imai C, Kakihara T, Iwabuchi H, Tanaka A, Furukawa T, Uchiyama M
Pediatr Nephrol 2003 Apr;18(4):399-402. Epub 2003 Mar 21 doi: 10.1007/s00467-003-1081-9. PMID: 12700971
Suri DL, Tomlanovich SJ, Olson JL, Meyer TW
Am J Kidney Dis 2000 Apr;35(4):674-80. doi: 10.1016/s0272-6386(00)70015-1. PMID: 10739789
Cohen EP, Lawton CA, Moulder JE, Becker CG, Ash RC
Nephron 1993;64(4):626-35. doi: 10.1159/000187412. PMID: 8366991

Clinical prediction guides

Furuichi K, Yuzawa Y, Shimizu M, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T
Nephrol Dial Transplant 2018 Jan 1;33(1):138-148. doi: 10.1093/ndt/gfw417. PMID: 28340221
Kai H, Shimizu Y, Hagiwara M, Yoh K, Hirayama K, Yamagata K, Ohba S, Nagata M, Koyama A
J Nephrol 2006 Mar-Apr;19(2):215-9. PMID: 16736424
Imai C, Kakihara T, Iwabuchi H, Tanaka A, Furukawa T, Uchiyama M
Pediatr Nephrol 2003 Apr;18(4):399-402. Epub 2003 Mar 21 doi: 10.1007/s00467-003-1081-9. PMID: 12700971
Iwafuchi Y, Morita T, Kamimura A, Kunisada K, Ito K, Miyazaki S
Clin Nephrol 2002 Mar;57(3):246-50. PMID: 11924757
Yasuda T, Imai H, Nakamoto Y, Miura AB, Inomata S
Virchows Arch A Pathol Anat Histopathol 1992;421(4):297-303. doi: 10.1007/BF01660976. PMID: 1329309

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