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t(1;10)(p22;q24)

MedGen UID:
1785900
•Concept ID:
C5446904
•
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that refers to the translocation of the short arm (p22) of chromosome 1 and the long arm (q24) of chromosome 10. It is associated with TGFBR3/OGA (MGEA5) fusions and some cases of pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts, hemosiderotic fibrolipomatous tumor (HFLT), myxoinflammatory fibroblastic sarcoma (MIFS) and hybrid HFLT/MIFS. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(1;10)(p22;q24)

Professional guidelines

PubMed

Recent Advances in the Diagnosis, Pathogenesis, and Management of Myxoinflammatory Fibroblastic Sarcoma.
Nishio J, Nakayama S, Aoki M
Int J Mol Sci 2024 Jan 17;25(2) doi: 10.3390/ijms25021127. PMID: 38256198Free PMC Article

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