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Chromosomal translocation

MedGen UID:
21243
Concept ID:
C0040715
Cell or Molecular Dysfunction
Synonyms: Chromosomal Translocation; Chromosomal Translocations; Genetic Translocation; Genetic Translocations; Translocation, Chromosomal; Translocation, Genetic; Translocations, Chromosomal; Translocations, Genetic
SNOMED CT: Chromosomal translocation (15897004)

Definition

A genetic exchange where a piece of one chromosome is transferred to another chromosome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChromosomal translocation

Professional guidelines

PubMed

French CA
Pathol Int 2018 Nov;68(11):583-595. Epub 2018 Oct 26 doi: 10.1111/pin.12727. PMID: 30362654
Vose JM
Am J Hematol 2017 Aug;92(8):806-813. doi: 10.1002/ajh.24797. PMID: 28699667
Vose JM
Am J Hematol 2015 Aug;90(8):739-45. doi: 10.1002/ajh.24094. PMID: 26103436

Recent clinical studies

Etiology

Kontomanolis EN, Koutras A, Syllaios A, Schizas D, Mastoraki A, Garmpis N, Diakosavvas M, Angelou K, Tsatsaris G, Pagkalos A, Ntounis T, Fasoulakis Z
Anticancer Res 2020 Nov;40(11):6009-6015. doi: 10.21873/anticanres.14622. PMID: 33109539
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752
Vose JM
Am J Hematol 2017 Aug;92(8):806-813. doi: 10.1002/ajh.24797. PMID: 28699667
Katoh M, Igarashi M, Fukuda H, Nakagama H, Katoh M
Cancer Lett 2013 Jan 28;328(2):198-206. Epub 2012 Sep 27 doi: 10.1016/j.canlet.2012.09.017. PMID: 23022474
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S
Lancet 2012 Mar 31;379(9822):1234-44. Epub 2012 Feb 13 doi: 10.1016/S0140-6736(11)61177-X. PMID: 22333947

Diagnosis

Gazendam AM, Popovic S, Munir S, Parasu N, Wilson D, Ghert M
Curr Oncol 2021 May 19;28(3):1909-1920. doi: 10.3390/curroncol28030177. PMID: 34069748Free PMC Article
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752
French CA
Pathol Int 2018 Nov;68(11):583-595. Epub 2018 Oct 26 doi: 10.1111/pin.12727. PMID: 30362654
Lee ATJ, Thway K, Huang PH, Jones RL
J Clin Oncol 2018 Jan 10;36(2):151-159. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9598. PMID: 29220294Free PMC Article
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246

Therapy

Hu Y, Zhou Y, Zhang M, Ge W, Li Y, Yang L, Wei G, Han L, Wang H, Yu S, Chen Y, Wang Y, He X, Zhang X, Gao M, Yang J, Li X, Ren J, Huang H
Clin Cancer Res 2021 May 15;27(10):2764-2772. Epub 2021 Feb 24 doi: 10.1158/1078-0432.CCR-20-3863. PMID: 33627493
Li K, Wang F, Yang ZN, Zhang TT, Yuan YF, Zhao CX, Yeerjiang Z, Cui B, Hua F, Lv XX, Zhang XW, Yu JJ, Liu SS, Yu JM, Shang S, Xiao Y, Hu ZW
Nat Commun 2020 Dec 9;11(1):6316. doi: 10.1038/s41467-020-20107-1. PMID: 33298911Free PMC Article
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752
Katoh M, Nakagama H
Med Res Rev 2014 Mar;34(2):280-300. Epub 2013 May 21 doi: 10.1002/med.21288. PMID: 23696246
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S
Lancet 2012 Mar 31;379(9822):1234-44. Epub 2012 Feb 13 doi: 10.1016/S0140-6736(11)61177-X. PMID: 22333947

Prognosis

Gazendam AM, Popovic S, Munir S, Parasu N, Wilson D, Ghert M
Curr Oncol 2021 May 19;28(3):1909-1920. doi: 10.3390/curroncol28030177. PMID: 34069748Free PMC Article
Meng X, Min Q, Wang JY
Adv Exp Med Biol 2020;1254:161-181. doi: 10.1007/978-981-15-3532-1_12. PMID: 32323276
Lee ATJ, Thway K, Huang PH, Jones RL
J Clin Oncol 2018 Jan 10;36(2):151-159. Epub 2017 Dec 8 doi: 10.1200/JCO.2017.74.9598. PMID: 29220294Free PMC Article
Chereda B, Melo JV
Ann Hematol 2015 Apr;94 Suppl 2:S107-21. Epub 2015 Mar 27 doi: 10.1007/s00277-015-2325-z. PMID: 25814077
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S
Lancet 2012 Mar 31;379(9822):1234-44. Epub 2012 Feb 13 doi: 10.1016/S0140-6736(11)61177-X. PMID: 22333947

Clinical prediction guides

Gazendam AM, Popovic S, Munir S, Parasu N, Wilson D, Ghert M
Curr Oncol 2021 May 19;28(3):1909-1920. doi: 10.3390/curroncol28030177. PMID: 34069748Free PMC Article
Mayeur A, Ahdad N, Hesters L, Brisset S, Romana S, Tosca L, Tachdjian G, Frydman N
Reprod Biomed Online 2019 Jan;38(1):46-55. Epub 2018 Nov 13 doi: 10.1016/j.rbmo.2018.10.003. PMID: 30518499
Nakano K, Takahashi S
Int J Mol Sci 2018 Nov 28;19(12) doi: 10.3390/ijms19123784. PMID: 30487384Free PMC Article
Vose JM
Am J Hematol 2017 Aug;92(8):806-813. doi: 10.1002/ajh.24797. PMID: 28699667
Ma ES
Methods Mol Biol 2017;1541:279-293. doi: 10.1007/978-1-4939-6703-2_22. PMID: 27910030

Recent systematic reviews

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