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Posttraumatic stress symptom

MedGen UID:
1787308
Concept ID:
C5539757
Mental or Behavioral Dysfunction
Synonym: PTSD
 
HPO: HP:0033676

Definition

A behavioral or psychological symptom that typically occurs following exposure to one or more traumatic events is posttraumatic stress disorder (PTSD). Symptoms of PTSD include intrusive recollections, such as re-experiencing the trauma through flashbacks, memories, or nightmares. Additionally, individuals may experience avoidant and numbing symptoms, which can include diminished emotions and avoidance of situations that serve as reminders of the traumatic event. Hyperarousal is another symptom, characterized by increased irritability, exaggerated startle reactions, and difficulties with sleeping or concentrating. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosttraumatic stress symptom

Professional guidelines

PubMed

McCarthy MC, Marks IR, Mulraney M, Downie P, Matson A, De Luca CR
Pediatr Blood Cancer 2021 Nov;68(11):e29302. Epub 2021 Aug 19 doi: 10.1002/pbc.29302. PMID: 34411413
Lakin DP, Win KS, Aung H, Soe KNC, Kyi B, Marcell AV, Tol WA, Bass JK
BMC Public Health 2021 Jan 25;21(1):211. doi: 10.1186/s12889-021-10249-2. PMID: 33494730Free PMC Article
Sabin JA, Zatzick DF, Jurkovich G, Rivara FP
Pediatrics 2006 Jan;117(1):130-8. doi: 10.1542/peds.2005-1042. PMID: 16396870

Recent clinical studies

Etiology

Dewar M, Paradis A, Brillon P
Psychol Trauma 2023 Sep;15(Suppl 2):S418-S426. Epub 2023 May 1 doi: 10.1037/tra0001512. PMID: 37126046
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Thomas JL, Cleveland S, Pietrzak RH, Dunkel Schetter C, Sumner JA
J Affect Disord 2021 Nov 1;294:314-321. Epub 2021 Jul 18 doi: 10.1016/j.jad.2021.07.025. PMID: 34311331Free PMC Article
Bartlett BA, Smith LJ, Tran JK, Vujanovic AA
Psychiatry Res 2018 Sep;267:394-399. Epub 2018 Jun 28 doi: 10.1016/j.psychres.2018.06.020. PMID: 29960261

Diagnosis

Dewar M, Paradis A, Brillon P
Psychol Trauma 2023 Sep;15(Suppl 2):S418-S426. Epub 2023 May 1 doi: 10.1037/tra0001512. PMID: 37126046
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Thomas JL, Cleveland S, Pietrzak RH, Dunkel Schetter C, Sumner JA
J Affect Disord 2021 Nov 1;294:314-321. Epub 2021 Jul 18 doi: 10.1016/j.jad.2021.07.025. PMID: 34311331Free PMC Article
Bartlett BA, Smith LJ, Tran JK, Vujanovic AA
Psychiatry Res 2018 Sep;267:394-399. Epub 2018 Jun 28 doi: 10.1016/j.psychres.2018.06.020. PMID: 29960261
Medina JL, Vujanovic AA, Smits JA, Irons JG, Zvolensky MJ, Bonn-Miller MO
Addict Behav 2011 Mar;36(3):274-7. Epub 2010 Nov 10 doi: 10.1016/j.addbeh.2010.11.008. PMID: 21111538Free PMC Article

Therapy

Marx BP, Fina BA, Sloan DM, Young-McCaughan S, Dondanville KA, Tyler HC, Blankenship AE, Schrader CC, Kaplan AM, Green VR, Bryan CJ, Hale WJ, Mintz J, Peterson AL; STRONG STAR Consortium
Contemp Clin Trials 2021 Nov;110:106564. Epub 2021 Sep 5 doi: 10.1016/j.cct.2021.106564. PMID: 34496277
Dawson RL, Calear AL, McCallum SM, McKenna S, Nixon RDV, O'Kearney R
J Trauma Stress 2021 Feb;34(1):81-91. Epub 2020 Oct 11 doi: 10.1002/jts.22596. PMID: 33043507
Kibler JL, Ma M, Tursich M, Malcolm L, Llabre MM, Greenbarg R, Gold SN, Beckham JC
J Affect Disord 2018 Dec 1;241:147-153. Epub 2018 Aug 7 doi: 10.1016/j.jad.2018.08.007. PMID: 30121447Free PMC Article
Gruebner O, Lowe SR, Tracy M, Joshi S, Cerdá M, Norris FH, Subramanian SV, Galea S
Sci Rep 2016 Aug 25;6:32242. doi: 10.1038/srep32242. PMID: 27558011Free PMC Article
Zandberg LJ, Rosenfield D, McLean CP, Powers MB, Asnaani A, Foa EB
J Consult Clin Psychol 2016 Jan;84(1):43-56. Epub 2015 Oct 12 doi: 10.1037/ccp0000052. PMID: 26460570Free PMC Article

Prognosis

Fares-Otero NE, Sharp TH, Balle SR, Quaatz SM, Vieta E, Åhs F, Allgaier AK, Arévalo A, Bachem R, Belete H, Mossie TB, Berzengi A, Capraz N, Ceylan D, Dukes D, Essadek A, Iqbal N, Jobson L, Levy-Gigi E, Lüönd A, Martin-Soelch C, Michael T, Oe M, Olff M, Örnkloo H, Prakash K, Ramakrishnan M, Raghavan V, Şar V, Seedat S, Spies G, SusilKumar V, Wadji DL, Wamser-Nanney R, Haim-Nachum S, Schnyder U, Sopp MR, Pfaltz MC, Halligan SL
Eur J Psychotraumatol 2024;15(1):2398921. Epub 2024 Oct 15 doi: 10.1080/20008066.2024.2398921. PMID: 39403959Free PMC Article
Dewar M, Paradis A, Brillon P
Psychol Trauma 2023 Sep;15(Suppl 2):S418-S426. Epub 2023 May 1 doi: 10.1037/tra0001512. PMID: 37126046
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Lai BS, Lewis R, Livings MS, La Greca AM, Esnard AM
J Trauma Stress 2017 Dec;30(6):571-582. Epub 2017 Nov 28 doi: 10.1002/jts.22242. PMID: 29193316Free PMC Article

Clinical prediction guides

Fares-Otero NE, Sharp TH, Balle SR, Quaatz SM, Vieta E, Åhs F, Allgaier AK, Arévalo A, Bachem R, Belete H, Mossie TB, Berzengi A, Capraz N, Ceylan D, Dukes D, Essadek A, Iqbal N, Jobson L, Levy-Gigi E, Lüönd A, Martin-Soelch C, Michael T, Oe M, Olff M, Örnkloo H, Prakash K, Ramakrishnan M, Raghavan V, Şar V, Seedat S, Spies G, SusilKumar V, Wadji DL, Wamser-Nanney R, Haim-Nachum S, Schnyder U, Sopp MR, Pfaltz MC, Halligan SL
Eur J Psychotraumatol 2024;15(1):2398921. Epub 2024 Oct 15 doi: 10.1080/20008066.2024.2398921. PMID: 39403959Free PMC Article
Dewar M, Paradis A, Brillon P
Psychol Trauma 2023 Sep;15(Suppl 2):S418-S426. Epub 2023 May 1 doi: 10.1037/tra0001512. PMID: 37126046
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Medina JL, Vujanovic AA, Smits JA, Irons JG, Zvolensky MJ, Bonn-Miller MO
Addict Behav 2011 Mar;36(3):274-7. Epub 2010 Nov 10 doi: 10.1016/j.addbeh.2010.11.008. PMID: 21111538Free PMC Article

Recent systematic reviews

Dawson RL, Calear AL, McCallum SM, McKenna S, Nixon RDV, O'Kearney R
J Trauma Stress 2021 Feb;34(1):81-91. Epub 2020 Oct 11 doi: 10.1002/jts.22596. PMID: 33043507

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