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Refractory Ovarian Transitional Cell Carcinoma

MedGen UID:
1791625
•Concept ID:
C5555184
•
Neoplastic Process

Definition

Ovarian transitional cell carcinoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Ovarian Transitional Cell Carcinoma

Professional guidelines

PubMed

Bevacizumab combined with chemotherapy in the treatment of recurrence or platinum-refractory ovarian cancer: a retrospective study of 37 cases.
Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742

Recent clinical studies

Etiology

Bevacizumab combined with chemotherapy in the treatment of recurrence or platinum-refractory ovarian cancer: a retrospective study of 37 cases.
Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742
Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.
Pitakkarnkul S, Tangjitgamol S, Srijaipracharoen S, Manusirivithaya S, Pataradool K, Prutthiphongsit W, Khunnarong J, Thavaramara T
Asian Pac J Cancer Prev 2013;14(4):2421-7. doi: 10.7314/apjcp.2013.14.4.2421. PMID: 23725151
Salvage chemotherapy for refractory transitional cell carcinoma of the ovary (TCC).
Sweeten KM, Gershenson DM, Burke TW, Morris M, Levenback C, Silva EG
Gynecol Oncol 1995 Nov;59(2):211-5. doi: 10.1006/gyno.1995.0010. PMID: 7590475

Diagnosis

Poly (ADP-Ribose) Polymerase Inhibitors in Patients With Urothelial Cancer.
Gamba T, Paparo J, Panepinto O, Dionisio R, Di Maio M, Vignani F
Clin Genitourin Cancer 2023 Oct;21(5):509-516. Epub 2023 Jul 20 doi: 10.1016/j.clgc.2023.07.009. PMID: 37500375
Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumors of the ovary.
Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA
Mod Pathol 2021 May;34(5):983-993. Epub 2020 Oct 19 doi: 10.1038/s41379-020-00699-1. PMID: 33077920
Bevacizumab combined with chemotherapy in the treatment of recurrence or platinum-refractory ovarian cancer: a retrospective study of 37 cases.
Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742
Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.
Pitakkarnkul S, Tangjitgamol S, Srijaipracharoen S, Manusirivithaya S, Pataradool K, Prutthiphongsit W, Khunnarong J, Thavaramara T
Asian Pac J Cancer Prev 2013;14(4):2421-7. doi: 10.7314/apjcp.2013.14.4.2421. PMID: 23725151
Salvage chemotherapy for refractory transitional cell carcinoma of the ovary (TCC).
Sweeten KM, Gershenson DM, Burke TW, Morris M, Levenback C, Silva EG
Gynecol Oncol 1995 Nov;59(2):211-5. doi: 10.1006/gyno.1995.0010. PMID: 7590475

Therapy

Poly (ADP-Ribose) Polymerase Inhibitors in Patients With Urothelial Cancer.
Gamba T, Paparo J, Panepinto O, Dionisio R, Di Maio M, Vignani F
Clin Genitourin Cancer 2023 Oct;21(5):509-516. Epub 2023 Jul 20 doi: 10.1016/j.clgc.2023.07.009. PMID: 37500375
Bevacizumab combined with chemotherapy in the treatment of recurrence or platinum-refractory ovarian cancer: a retrospective study of 37 cases.
Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742
Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.
Pitakkarnkul S, Tangjitgamol S, Srijaipracharoen S, Manusirivithaya S, Pataradool K, Prutthiphongsit W, Khunnarong J, Thavaramara T
Asian Pac J Cancer Prev 2013;14(4):2421-7. doi: 10.7314/apjcp.2013.14.4.2421. PMID: 23725151
Substantial activity of mitoxantrone and paclitaxel in a heavily pre-treated metastatic bladder cancer patient.
Schmeeckle KD, Kim JW, Sartor O
J La State Med Soc 2008 Jan-Feb;160(1):17-8. PMID: 18669404
Salvage chemotherapy for refractory transitional cell carcinoma of the ovary (TCC).
Sweeten KM, Gershenson DM, Burke TW, Morris M, Levenback C, Silva EG
Gynecol Oncol 1995 Nov;59(2):211-5. doi: 10.1006/gyno.1995.0010. PMID: 7590475

Prognosis

Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumors of the ovary.
Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA
Mod Pathol 2021 May;34(5):983-993. Epub 2020 Oct 19 doi: 10.1038/s41379-020-00699-1. PMID: 33077920
Bevacizumab combined with chemotherapy in the treatment of recurrence or platinum-refractory ovarian cancer: a retrospective study of 37 cases.
Li Y, Yang Y, Shang YM, Zheng H
Indian J Cancer 2014 Mar;51 Suppl 3:e92-4. doi: 10.4103/0019-509X.154079. PMID: 25818742
Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.
Pitakkarnkul S, Tangjitgamol S, Srijaipracharoen S, Manusirivithaya S, Pataradool K, Prutthiphongsit W, Khunnarong J, Thavaramara T
Asian Pac J Cancer Prev 2013;14(4):2421-7. doi: 10.7314/apjcp.2013.14.4.2421. PMID: 23725151
Telomerase is frequently activated in tumors with microsatellite instability.
Ibanez de Caceres I, Frolova N, Varkonyi RJ, Dulaimi E, Meropol NJ, Broccoli D, Cairns P
Cancer Biol Ther 2004 Mar;3(3):289-92. Epub 2004 Mar 10 doi: 10.4161/cbt.3.3.695. PMID: 14726659
Salvage chemotherapy for refractory transitional cell carcinoma of the ovary (TCC).
Sweeten KM, Gershenson DM, Burke TW, Morris M, Levenback C, Silva EG
Gynecol Oncol 1995 Nov;59(2):211-5. doi: 10.1006/gyno.1995.0010. PMID: 7590475

Clinical prediction guides

Treatment outcomes of paclitaxel for refractory or recurrent epithelial ovarian cancer patients in Thailand.
Pitakkarnkul S, Tangjitgamol S, Srijaipracharoen S, Manusirivithaya S, Pataradool K, Prutthiphongsit W, Khunnarong J, Thavaramara T
Asian Pac J Cancer Prev 2013;14(4):2421-7. doi: 10.7314/apjcp.2013.14.4.2421. PMID: 23725151
Telomerase is frequently activated in tumors with microsatellite instability.
Ibanez de Caceres I, Frolova N, Varkonyi RJ, Dulaimi E, Meropol NJ, Broccoli D, Cairns P
Cancer Biol Ther 2004 Mar;3(3):289-92. Epub 2004 Mar 10 doi: 10.4161/cbt.3.3.695. PMID: 14726659
Salvage chemotherapy for refractory transitional cell carcinoma of the ovary (TCC).
Sweeten KM, Gershenson DM, Burke TW, Morris M, Levenback C, Silva EG
Gynecol Oncol 1995 Nov;59(2):211-5. doi: 10.1006/gyno.1995.0010. PMID: 7590475

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