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Recurrent Diffuse Midline Glioma, H3 K27M-Mutant

MedGen UID:
1791979
Concept ID:
C5555538
Neoplastic Process

Definition

The reemergence of diffuse midline glioma, H3 K27M mutant, after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Diffuse Midline Glioma, H3 K27M-Mutant

Recent clinical studies

Etiology

Chiba K, Aihara Y, Masui K, Abe K, Komori T, Kawamata T
World Neurosurg 2020 Feb;134:e530-e539. Epub 2019 Nov 5 doi: 10.1016/j.wneu.2019.10.116. PMID: 31704359
Chi AS, Tarapore RS, Hall MD, Shonka N, Gardner S, Umemura Y, Sumrall A, Khatib Z, Mueller S, Kline C, Zaky W, Khatua S, Weathers SP, Odia Y, Niazi TN, Daghistani D, Cherrick I, Korones D, Karajannis MA, Kong XT, Minturn J, Waanders A, Arillaga-Romany I, Batchelor T, Wen PY, Merdinger K, Schalop L, Stogniew M, Allen JE, Oster W, Mehta MP
J Neurooncol 2019 Oct;145(1):97-105. Epub 2019 Aug 27 doi: 10.1007/s11060-019-03271-3. PMID: 31456142Free PMC Article
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA
Acta Neuropathol 2015 Dec;130(6):815-27. Epub 2015 Sep 23 doi: 10.1007/s00401-015-1478-0. PMID: 26399631Free PMC Article

Diagnosis

He P, Chen W, Qiu XX, Xi YB, Guan H, Xia J
World Neurosurg 2019 Aug;128:527-531. Epub 2019 Apr 29 doi: 10.1016/j.wneu.2019.04.172. PMID: 31048046
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA
Acta Neuropathol 2015 Dec;130(6):815-27. Epub 2015 Sep 23 doi: 10.1007/s00401-015-1478-0. PMID: 26399631Free PMC Article

Therapy

Chi AS, Tarapore RS, Hall MD, Shonka N, Gardner S, Umemura Y, Sumrall A, Khatib Z, Mueller S, Kline C, Zaky W, Khatua S, Weathers SP, Odia Y, Niazi TN, Daghistani D, Cherrick I, Korones D, Karajannis MA, Kong XT, Minturn J, Waanders A, Arillaga-Romany I, Batchelor T, Wen PY, Merdinger K, Schalop L, Stogniew M, Allen JE, Oster W, Mehta MP
J Neurooncol 2019 Oct;145(1):97-105. Epub 2019 Aug 27 doi: 10.1007/s11060-019-03271-3. PMID: 31456142Free PMC Article

Prognosis

Vaubel RA, Tian S, Remonde D, Schroeder MA, Mladek AC, Kitange GJ, Caron A, Kollmeyer TM, Grove R, Peng S, Carlson BL, Ma DJ, Sarkar G, Evers L, Decker PA, Yan H, Dhruv HD, Berens ME, Wang Q, Marin BM, Klee EW, Califano A, LaChance DH, Eckel-Passow JE, Verhaak RG, Sulman EP, Burns TC, Meyer FB, O'Neill BP, Tran NL, Giannini C, Jenkins RB, Parney IF, Sarkaria JN
Clin Cancer Res 2020 Mar 1;26(5):1094-1104. Epub 2019 Dec 18 doi: 10.1158/1078-0432.CCR-19-0909. PMID: 31852831Free PMC Article
Chiba K, Aihara Y, Masui K, Abe K, Komori T, Kawamata T
World Neurosurg 2020 Feb;134:e530-e539. Epub 2019 Nov 5 doi: 10.1016/j.wneu.2019.10.116. PMID: 31704359
Chi AS, Tarapore RS, Hall MD, Shonka N, Gardner S, Umemura Y, Sumrall A, Khatib Z, Mueller S, Kline C, Zaky W, Khatua S, Weathers SP, Odia Y, Niazi TN, Daghistani D, Cherrick I, Korones D, Karajannis MA, Kong XT, Minturn J, Waanders A, Arillaga-Romany I, Batchelor T, Wen PY, Merdinger K, Schalop L, Stogniew M, Allen JE, Oster W, Mehta MP
J Neurooncol 2019 Oct;145(1):97-105. Epub 2019 Aug 27 doi: 10.1007/s11060-019-03271-3. PMID: 31456142Free PMC Article
He P, Chen W, Qiu XX, Xi YB, Guan H, Xia J
World Neurosurg 2019 Aug;128:527-531. Epub 2019 Apr 29 doi: 10.1016/j.wneu.2019.04.172. PMID: 31048046
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA
Acta Neuropathol 2015 Dec;130(6):815-27. Epub 2015 Sep 23 doi: 10.1007/s00401-015-1478-0. PMID: 26399631Free PMC Article

Clinical prediction guides

Chiba K, Aihara Y, Masui K, Abe K, Komori T, Kawamata T
World Neurosurg 2020 Feb;134:e530-e539. Epub 2019 Nov 5 doi: 10.1016/j.wneu.2019.10.116. PMID: 31704359
He P, Chen W, Qiu XX, Xi YB, Guan H, Xia J
World Neurosurg 2019 Aug;128:527-531. Epub 2019 Apr 29 doi: 10.1016/j.wneu.2019.04.172. PMID: 31048046
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA
Acta Neuropathol 2015 Dec;130(6):815-27. Epub 2015 Sep 23 doi: 10.1007/s00401-015-1478-0. PMID: 26399631Free PMC Article

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