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Peritoneal Sarcomatosis

MedGen UID:
1792288
•Concept ID:
C5555847
•
Neoplastic Process

Definition

A condition in which a sarcoma has spread extensively throughout the peritoneum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeritoneal Sarcomatosis

Professional guidelines

PubMed

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the management of peritoneal surface malignancies - An evidence-based review.
Ray MD, Dhall K
Curr Probl Cancer 2021 Dec;45(6):100737. Epub 2021 Apr 15 doi: 10.1016/j.currproblcancer.2021.100737. PMID: 34116836
Aggressive locoregional management of recurrent peritoneal sarcomatosis.
Baumgartner JM, Ahrendt SA, Pingpank JF, Holtzman MP, Ramalingam L, Jones HL, Zureikat AH, Zeh HJ 3rd, Bartlett DL, Choudry HA
J Surg Oncol 2013 Mar;107(4):329-34. Epub 2013 Feb 5 doi: 10.1002/jso.23232. PMID: 23386388
Systematic review on the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy.
Munene G, Mack LA, Temple WJ
Ann Surg Oncol 2011 Jan;18(1):207-13. Epub 2010 Aug 10 doi: 10.1245/s10434-010-1229-3. PMID: 20697824

Recent clinical studies

Etiology

Macroscopically complete excision is a beneficial strategy for selected patients with peritoneal sarcomatosis.
Li Y, Lv A, Wu J, Li C, Liu B, Tian X, Qiu H, Hao C
Biosci Trends 2022 Jan 23;15(6):382-389. Epub 2021 Nov 26 doi: 10.5582/bst.2021.01421. PMID: 34840236
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal sarcomatosis-A systematic review and meta-analysis.
Wong LCK, Li Z, Fan Q, Tan JW, Tan QX, Wong JSM, Ong CJ, Chia CS
Eur J Surg Oncol 2022 Mar;48(3):640-648. Epub 2021 Oct 15 doi: 10.1016/j.ejso.2021.10.013. PMID: 34716035
Hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecological cancer.
Tsuyoshi H, Inoue D, Kurokawa T, Yoshida Y
J Obstet Gynaecol Res 2020 Sep;46(9):1661-1671. Epub 2020 Jul 26 doi: 10.1111/jog.14391. PMID: 32715605
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal sarcomatosis.
Salti GI, Ailabouni L, Undevia S
Ann Surg Oncol 2012 May;19(5):1410-5. doi: 10.1245/s10434-012-2240-7. PMID: 22302269
Retroperitoneal synovial sarcoma. A report of four cases.
Shmookler BM
Am J Clin Pathol 1982 Jun;77(6):686-91. doi: 10.1093/ajcp/77.6.686. PMID: 6283877

Diagnosis

Peritoneal sarcomatosis due to undifferentiated pleomorphic sarcoma: A case report and review of the literature.
Sogutcu N, Kavak S, Gumus S
Indian J Pathol Microbiol 2023 Apr-Jun;66(2):356-359. doi: 10.4103/ijpm.ijpm_267_21. PMID: 37077083
A rare colorectal entity: Colonic leiomyosarcoma with peritoneal sarcomatosis.
White RZ, Au J, Hunter A, Vather R
ANZ J Surg 2022 Mar;92(3):571-573. Epub 2021 Jul 20 doi: 10.1111/ans.17079. PMID: 34288339
Peritoneal lymphomatosis: CT and PET/CT findings and how to differentiate between carcinomatosis and sarcomatosis.
Cabral FC, Krajewski KM, Kim KW, Ramaiya NH, Jagannathan JP
Cancer Imaging 2013 Apr 15;13(2):162-70. doi: 10.1102/1470-7330.2013.0018. PMID: 23598428Free PMC Article
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal sarcomatosis.
Salti GI, Ailabouni L, Undevia S
Ann Surg Oncol 2012 May;19(5):1410-5. doi: 10.1245/s10434-012-2240-7. PMID: 22302269
Peritoneal sarcomatosis versus peritoneal carcinomatosis: imaging findings at MDCT.
Oei TN, Jagannathan JP, Ramaiya N, Ros PR
AJR Am J Roentgenol 2010 Sep;195(3):W229-35. doi: 10.2214/AJR.09.3907. PMID: 20729420

Therapy

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal sarcomatosis-A systematic review and meta-analysis.
Wong LCK, Li Z, Fan Q, Tan JW, Tan QX, Wong JSM, Ong CJ, Chia CS
Eur J Surg Oncol 2022 Mar;48(3):640-648. Epub 2021 Oct 15 doi: 10.1016/j.ejso.2021.10.013. PMID: 34716035
Bleeding "sarcomatosis" as a rare presentation of vascular graft-related angiosarcoma: case report and review of the literature.
Presacco S, Agnes AL, Magalini S, Carbone A, Martini M, Agnes A
BMC Surg 2020 Nov 20;20(1):291. doi: 10.1186/s12893-020-00966-7. PMID: 33218319Free PMC Article
Hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecological cancer.
Tsuyoshi H, Inoue D, Kurokawa T, Yoshida Y
J Obstet Gynaecol Res 2020 Sep;46(9):1661-1671. Epub 2020 Jul 26 doi: 10.1111/jog.14391. PMID: 32715605
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal sarcomatosis.
Salti GI, Ailabouni L, Undevia S
Ann Surg Oncol 2012 May;19(5):1410-5. doi: 10.1245/s10434-012-2240-7. PMID: 22302269
Systematic review on the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy.
Munene G, Mack LA, Temple WJ
Ann Surg Oncol 2011 Jan;18(1):207-13. Epub 2010 Aug 10 doi: 10.1245/s10434-010-1229-3. PMID: 20697824

Prognosis

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal sarcomatosis-A systematic review and meta-analysis.
Wong LCK, Li Z, Fan Q, Tan JW, Tan QX, Wong JSM, Ong CJ, Chia CS
Eur J Surg Oncol 2022 Mar;48(3):640-648. Epub 2021 Oct 15 doi: 10.1016/j.ejso.2021.10.013. PMID: 34716035
18F-FDG PET/CT for Monitoring of Disease Progression in Metastatic Perivascular Epithelioid Cell Tumor.
Holzgreve A, Fabritius MP, Knösel T, Renz BW, Lindner LH, Di Gioia D, Bartenstein P, Rübenthaler J, Tiling R
Clin Nucl Med 2021 Feb 1;46(2):156-158. doi: 10.1097/RLU.0000000000003453. PMID: 33315683
The value of re-exploration in patients with inadvertently morcellated uterine sarcoma.
Oduyebo T, Rauh-Hain AJ, Meserve EE, Seidman MA, Hinchcliff E, George S, Quade B, Nucci MR, Del Carmen MG, Muto MG
Gynecol Oncol 2014 Feb;132(2):360-5. Epub 2013 Dec 1 doi: 10.1016/j.ygyno.2013.11.024. PMID: 24296345
Systematic review on the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy.
Munene G, Mack LA, Temple WJ
Ann Surg Oncol 2011 Jan;18(1):207-13. Epub 2010 Aug 10 doi: 10.1245/s10434-010-1229-3. PMID: 20697824
Melanotic peritoneal sarcomatosis originating from clear cell sarcoma.
Ohba Y, Suzuki H, Hiraga H, Ito T, Sawa H, Nagai M, Satoh SI, Iwaki H, Nagashima K
Pathol Int 1999 Jul;49(7):653-7. doi: 10.1046/j.1440-1827.1999.00916.x. PMID: 10504528

Clinical prediction guides

Macroscopically complete excision is a beneficial strategy for selected patients with peritoneal sarcomatosis.
Li Y, Lv A, Wu J, Li C, Liu B, Tian X, Qiu H, Hao C
Biosci Trends 2022 Jan 23;15(6):382-389. Epub 2021 Nov 26 doi: 10.5582/bst.2021.01421. PMID: 34840236
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the management of peritoneal surface malignancies - An evidence-based review.
Ray MD, Dhall K
Curr Probl Cancer 2021 Dec;45(6):100737. Epub 2021 Apr 15 doi: 10.1016/j.currproblcancer.2021.100737. PMID: 34116836
Hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecological cancer.
Tsuyoshi H, Inoue D, Kurokawa T, Yoshida Y
J Obstet Gynaecol Res 2020 Sep;46(9):1661-1671. Epub 2020 Jul 26 doi: 10.1111/jog.14391. PMID: 32715605
Peritoneal sarcomatosis: site of origin for the establishment of an in vitro and in vivo cell line model to study therapeutic resistance in dedifferentiated liposarcoma.
Mersch S, Riemer JC, Schlünder PM, Ghadimi MP, Ashmawy H, Möhlendick B, Topp SA, Arent T, Kröpil P, Stoecklein NH, Gabbert HE, Knoefel WT, Krieg A
Tumour Biol 2016 Feb;37(2):2341-51. Epub 2015 Sep 15 doi: 10.1007/s13277-015-4050-6. PMID: 26373732
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal sarcomatosis.
Salti GI, Ailabouni L, Undevia S
Ann Surg Oncol 2012 May;19(5):1410-5. doi: 10.1245/s10434-012-2240-7. PMID: 22302269

Recent systematic reviews

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in peritoneal sarcomatosis-A systematic review and meta-analysis.
Wong LCK, Li Z, Fan Q, Tan JW, Tan QX, Wong JSM, Ong CJ, Chia CS
Eur J Surg Oncol 2022 Mar;48(3):640-648. Epub 2021 Oct 15 doi: 10.1016/j.ejso.2021.10.013. PMID: 34716035
Systematic review on the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy.
Munene G, Mack LA, Temple WJ
Ann Surg Oncol 2011 Jan;18(1):207-13. Epub 2010 Aug 10 doi: 10.1245/s10434-010-1229-3. PMID: 20697824

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