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Cervical Mucoepidermoid Carcinoma

MedGen UID:
1793125
Concept ID:
C5556684
Neoplastic Process

Definition

A rare carcinoma that arises from the cervix. It is characterized by the presence of squamous cells, mucus producing cells, and cells of intermediate type. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical Mucoepidermoid Carcinoma

Professional guidelines

PubMed

Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585

Recent clinical studies

Etiology

Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Nakano S, Okumura Y, Murase T, Nagao T, Kusafuka K, Urano M, Yamamoto H, Kano S, Tsukahara K, Okami K, Kawakita D, Nagao T, Hanai N, Iwai H, Kawata R, Tada Y, Nibu KI, Inagaki H
Histopathology 2022 Mar;80(4):729-735. Epub 2021 Dec 14 doi: 10.1111/his.14586. PMID: 34657306
Chan SA, Van Abel KM, Lewis JE, Routman DM, Garcia JJ, Karp EE, Price DL, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Sep;43(9):2663-2671. Epub 2021 May 1 doi: 10.1002/hed.26735. PMID: 33931913
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585

Diagnosis

Skálová A, Hyrcza MD, Leivo I
Head Neck Pathol 2022 Mar;16(1):40-53. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01420-1. PMID: 35312980Free PMC Article
Nakano S, Okumura Y, Murase T, Nagao T, Kusafuka K, Urano M, Yamamoto H, Kano S, Tsukahara K, Okami K, Kawakita D, Nagao T, Hanai N, Iwai H, Kawata R, Tada Y, Nibu KI, Inagaki H
Histopathology 2022 Mar;80(4):729-735. Epub 2021 Dec 14 doi: 10.1111/his.14586. PMID: 34657306
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Devaraju R, Gantala R, Aitha H, Gotoor SG
BMJ Case Rep 2014 Aug 1;2014:bcr-2013-202776. doi: 10.1136/bcr-2013-202776. PMID: 25085946Free PMC Article

Therapy

Chen Z, Liu G, Geng Y, Wu H
Int J Oral Maxillofac Surg 2022 Oct;51(10):1273-1278. Epub 2022 Feb 1 doi: 10.1016/j.ijom.2022.01.015. PMID: 35120787
Schvartsman G, Pinto NA, Bell D, Ferrarotto R
Head Neck 2019 Jan;41(1):239-247. Epub 2018 Dec 15 doi: 10.1002/hed.25468. PMID: 30552848
Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903
Alamri AM, Liu X, Blancato JK, Haddad BR, Wang W, Zhong X, Choudhary S, Krawczyk E, Kallakury BV, Davidson BJ, Furth PA
Dis Model Mech 2018 Jan 29;11(1) doi: 10.1242/dmm.031716. PMID: 29419396Free PMC Article
Shirai K, Koto M, Demizu Y, Suefuji H, Ohno T, Tsuji H, Okimoto T, Shioyama Y, Saitoh JI, Nemoto K, Nakano T, Kamada T; Japan Carbon-Ion Radiation Oncology Study Group
Cancer Sci 2017 Jul;108(7):1447-1451. Epub 2017 May 29 doi: 10.1111/cas.13270. PMID: 28474791Free PMC Article

Prognosis

Hay AJ, Migliacci J, Karassawa Zanoni D, McGill M, Patel S, Ganly I
Cancer 2019 Oct 1;125(19):3354-3366. Epub 2019 Jun 7 doi: 10.1002/cncr.32208. PMID: 31174233Free PMC Article
Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Coca-Pelaz A, Rodrigo JP, Triantafyllou A, Hunt JL, Rinaldo A, Strojan P, Haigentz M Jr, Mendenhall WM, Takes RP, Vander Poorten V, Ferlito A
Eur Arch Otorhinolaryngol 2015 Apr;272(4):799-819. Epub 2014 Apr 26 doi: 10.1007/s00405-014-3053-z. PMID: 24771140

Clinical prediction guides

Kaur K, Mehta S, Vanik S, Trivedi P, Banerjee N, Dhar H, Datta S, Karanjai S
Eur Arch Otorhinolaryngol 2022 Aug;279(8):3769-3783. Epub 2022 Mar 10 doi: 10.1007/s00405-022-07326-6. PMID: 35267084
Reny DC, Ranasinghe VJ, Magana LC, Kaufman AC, Chalian AA, O'Malley BW Jr, Weinstein GS, Brody RM
ORL J Otorhinolaryngol Relat Spec 2020;82(6):327-334. Epub 2020 Aug 18 doi: 10.1159/000509142. PMID: 32810854
Hay AJ, Migliacci J, Karassawa Zanoni D, McGill M, Patel S, Ganly I
Cancer 2019 Oct 1;125(19):3354-3366. Epub 2019 Jun 7 doi: 10.1002/cncr.32208. PMID: 31174233Free PMC Article
Skálová A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T, Bishop JA, Hunt JL, Nibu KI, Rinaldo A, Vander Poorten V, Devaney KO, Steiner P, Ferlito A
Am J Surg Pathol 2018 Feb;42(2):e11-e27. doi: 10.1097/PAS.0000000000000980. PMID: 29076877
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169

Recent systematic reviews

Keerthika R, Devi A, Kamboj M, Sivakumar N, Vijayakumar G, Narwal A, Girdhar A
Head Neck Pathol 2023 Mar;17(1):233-245. Epub 2022 Nov 10 doi: 10.1007/s12105-022-01494-x. PMID: 36357765Free PMC Article
Cheng EY, Kim JH, Grose EM, Philteos J, Levin M, de Almeida J, Goldstein D
Otolaryngol Head Neck Surg 2023 Apr;168(4):611-618. Epub 2023 Feb 5 doi: 10.1177/01945998221086845. PMID: 35316125
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Louredo BVR, Santos-Silva AR, Vargas PA, Ajudarte Lopes M, Martins MD, Guerra ENDS, Prado Ribeiro AC, Brandão TB, de Mendonça RMH, Kowalski LP, Speight PM, Khurram SA, Pérez-de-Oliveira ME
J Oral Pathol Med 2021 May;50(5):435-443. Epub 2021 Jan 8 doi: 10.1111/jop.13151. PMID: 33314344
Zamani M, Grønhøj C, Schmidt Jensen J, von Buchwald C, Charabi BW, Hjuler T
Pediatr Blood Cancer 2019 Mar;66(3):e27543. Epub 2018 Oct 30 doi: 10.1002/pbc.27543. PMID: 30378272

Supplemental Content

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