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Reduced circulating interleukin 22 concentration

MedGen UID:
1814332
Concept ID:
C5676763
Finding
HPO: HP:0034168

Definition

An abnormally decreased concentration of interleukin 22 in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced circulating interleukin 22 concentration

Conditions with this feature

Immunodeficiency 89 and autoimmunity
MedGen UID:
1794237
Concept ID:
C5562027
Disease or Syndrome
Immunodeficiency-89 and autoimmunity (IMD89) is an autosomal recessive immune disorder characterized by adult onset of recurrent infections, allergies, microcytic anemia, and Crohn disease (see 266600) (Yang et al., 2020).

Professional guidelines

PubMed

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article

Recent clinical studies

Diagnosis

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article

Therapy

Martonik D, Parfieniuk-Kowerda A, Starosz A, Grubczak K, Moniuszko M, Flisiak R
Front Immunol 2023;14:1222170. Epub 2023 Jul 6 doi: 10.3389/fimmu.2023.1222170. PMID: 37483627Free PMC Article

Clinical prediction guides

Zhang Y, Li Y, Lv TT, Yin ZJ, Wang XB
APMIS 2015 Aug;123(8):659-66. Epub 2015 Apr 27 doi: 10.1111/apm.12399. PMID: 25912557

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