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Oocyte maturation arrest

MedGen UID:
1838865
Concept ID:
C5826764
Cell or Molecular Dysfunction
HPO: HP:0034914

Definition

Oocyte maturation arrest (OMA) can manifest as failed in vitro fetilization/intracytoplasmic sperm injection (IVF/ICSI) attempts using affected oocytes. [from HPO]

Term Hierarchy

Conditions with this feature

Oocyte maturation defect 14
MedGen UID:
1840962
Concept ID:
C5830326
Disease or Syndrome
Oocyte/zygote/embryo maturation arrest-14 (OZEMA14) is characterized by female infertility due to oocyte maturation arrest, fertilization failure, and/or early embryonic arrest. The rare fertilized embryos that are transferred to the uterus fail to establish pregnancy after transfer (Zhao et al., 2020, Zhao et al., 2021, Huang et al., 2021, Xu et al., 2021). For a discussion of genetic heterogeneity of OZEMA, see 615774.

Professional guidelines

PubMed

Lin T, Liu W, Han W, Tong K, Xiang Y, Liao H, Chen K, He Y, Liu D, Huang G
Reprod Biomed Online 2023 Feb;46(2):244-254. Epub 2022 Oct 17 doi: 10.1016/j.rbmo.2022.10.008. PMID: 36463079
Ren Y, Lian Y, Yan Z, Zhai F, Yang M, Zhu X, Wang Y, Nie Y, Guan S, Kuo Y, Huang J, Shi X, Jia J, Qiao J, Yan L
J Assist Reprod Genet 2021 Aug;38(8):1979-1986. Epub 2021 Mar 15 doi: 10.1007/s10815-021-02126-z. PMID: 33719023Free PMC Article
Neri QV, Takeuchi T, Rosenwaks Z, Palermo GD
Minerva Ginecol 2009 Aug;61(4):253-9. PMID: 19745793

Recent clinical studies

Etiology

Li Q, Zhao L, Zeng Y, Kuang Y, Guan Y, Chen B, Xu S, Tang B, Wu L, Mao X, Sun X, Shi J, Xu P, Diao F, Xue S, Bao S, Meng Q, Yuan P, Wang W, Ma N, Song D, Xu B, Dong J, Mu J, Zhang Z, Fan H, Gu H, Li Q, He L, Jin L, Wang L, Sang Q
Genome Biol 2023 Apr 6;24(1):68. doi: 10.1186/s13059-023-02894-0. PMID: 37024973Free PMC Article
Mu L, Ye Z, Hu J, Zhang Y, Chen K, Sun H, Li R, Mao W, Long X, Zhang C, Lai Y, Liu J, Zhao Y, Qiao J
EBioMedicine 2023 Mar;89:104492. Epub 2023 Feb 28 doi: 10.1016/j.ebiom.2023.104492. PMID: 36863088Free PMC Article
Zhang H, Wang W, Zhao J, Jiao P, Zeng L, Zhang H, Zhao Y, Shi L, Hu H, Luo L, Fukuzawa I, Li D, Li R, Qiao J
Front Endocrinol (Lausanne) 2022;13:1085656. Epub 2023 Jan 9 doi: 10.3389/fendo.2022.1085656. PMID: 36699018Free PMC Article
Xu Y, Qiao J
J Healthc Eng 2022;2022:9240569. Epub 2022 Mar 21 doi: 10.1155/2022/9240569. PMID: 35356614Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031

Diagnosis

Huang L, Li W, Dai X, Zhao S, Xu B, Wang F, Jin RT, Luo L, Wu L, Jiang X, Cheng Y, Zou J, Xu C, Tong X, Fan HY, Zhao H, Bao J
Elife 2023 Jun 19;12 doi: 10.7554/eLife.85649. PMID: 37334967Free PMC Article
Li Q, Zhao L, Zeng Y, Kuang Y, Guan Y, Chen B, Xu S, Tang B, Wu L, Mao X, Sun X, Shi J, Xu P, Diao F, Xue S, Bao S, Meng Q, Yuan P, Wang W, Ma N, Song D, Xu B, Dong J, Mu J, Zhang Z, Fan H, Gu H, Li Q, He L, Jin L, Wang L, Sang Q
Genome Biol 2023 Apr 6;24(1):68. doi: 10.1186/s13059-023-02894-0. PMID: 37024973Free PMC Article
Zhang H, Wang W, Zhao J, Jiao P, Zeng L, Zhang H, Zhao Y, Shi L, Hu H, Luo L, Fukuzawa I, Li D, Li R, Qiao J
Front Endocrinol (Lausanne) 2022;13:1085656. Epub 2023 Jan 9 doi: 10.3389/fendo.2022.1085656. PMID: 36699018Free PMC Article
Zhu L, Yang Q, Jin H, Zhou J, Wang M, Yang L, Li Z, Qian K, Jin L
Front Endocrinol (Lausanne) 2022;13:1016563. Epub 2022 Nov 10 doi: 10.3389/fendo.2022.1016563. PMID: 36440233Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031

Therapy

Hatirnaz S, Hatirnaz E, Urkmez SS, Calıskan CS, Celik S, Hatirnaz K, Cao M, Tan SL, Dahan MH
Reprod Biomed Online 2024 Mar;48(3):103620. Epub 2023 Oct 14 doi: 10.1016/j.rbmo.2023.103620. PMID: 38194886
Mu L, Ye Z, Hu J, Zhang Y, Chen K, Sun H, Li R, Mao W, Long X, Zhang C, Lai Y, Liu J, Zhao Y, Qiao J
EBioMedicine 2023 Mar;89:104492. Epub 2023 Feb 28 doi: 10.1016/j.ebiom.2023.104492. PMID: 36863088Free PMC Article
Zhang H, Wang W, Zhao J, Jiao P, Zeng L, Zhang H, Zhao Y, Shi L, Hu H, Luo L, Fukuzawa I, Li D, Li R, Qiao J
Front Endocrinol (Lausanne) 2022;13:1085656. Epub 2023 Jan 9 doi: 10.3389/fendo.2022.1085656. PMID: 36699018Free PMC Article
Zhang C, Yan L, Qiao J
J Assist Reprod Genet 2022 Sep;39(9):1969-1986. Epub 2022 Aug 4 doi: 10.1007/s10815-022-02533-w. PMID: 35925538Free PMC Article
Qin X, Zhao Y, Zhang T, Yin C, Qiao J, Guo W, Lu B
Nat Commun 2022 Feb 17;13(1):914. doi: 10.1038/s41467-022-28611-2. PMID: 35177657Free PMC Article

Prognosis

Boroujeni PB, Rooney K, Alikhani M, Rahmati S, Feli G, Haratian K, Movaghar B, Meybodi AM
Reprod Biomed Online 2023 Oct;47(4):103226. Epub 2023 May 3 doi: 10.1016/j.rbmo.2023.04.017. PMID: 37597348
Shang C, Li Y, He T, Liao Y, Du Q, Wang P, Qiao J, Guo H
J Adv Res 2022 Mar;37:169-184. Epub 2021 Sep 22 doi: 10.1016/j.jare.2021.09.009. PMID: 35499057Free PMC Article
Yang P, Chen T, Wu K, Hou Z, Zou Y, Li M, Zhang X, Xu J, Zhao H
Hum Reprod 2021 Jun 18;36(7):2011-2019. doi: 10.1093/humrep/deab094. PMID: 33893736
Li Y, Liang Z, Liang Z, Yang X, Xia H, Yu H
Fertil Steril 2021 May;115(5):1318-1326. Epub 2021 Feb 20 doi: 10.1016/j.fertnstert.2020.11.037. PMID: 33622565
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031

Clinical prediction guides

Hatirnaz Ş, Hatirnaz E, Urkmez SS, Celik S, Urkmez' YC, Cao M, Tan SL, Dahan MH
Reprod Biomed Online 2024 Apr;48(4):103648. Epub 2023 Oct 29 doi: 10.1016/j.rbmo.2023.103648. PMID: 38364519
Hu T, Li C, Qiao S, Liu W, Han W, Li W, Shi R, Xue X, Shi J, Huang G, Lin T
J Ovarian Res 2023 Nov 25;16(1):228. doi: 10.1186/s13048-023-01274-3. PMID: 38007525Free PMC Article
Zhu L, Yang Q, Jin H, Zhou J, Wang M, Yang L, Li Z, Qian K, Jin L
Front Endocrinol (Lausanne) 2022;13:1016563. Epub 2022 Nov 10 doi: 10.3389/fendo.2022.1016563. PMID: 36440233Free PMC Article
Shang C, Li Y, He T, Liao Y, Du Q, Wang P, Qiao J, Guo H
J Adv Res 2022 Mar;37:169-184. Epub 2021 Sep 22 doi: 10.1016/j.jare.2021.09.009. PMID: 35499057Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031

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