U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Splenic hemophagocytosis

MedGen UID:
1841575
Concept ID:
C5826671
Finding
Synonym: Spleen hemophagocytosis
 
HPO: HP:0034799

Definition

Phagocytosis of erythrocytes, lymphocytes or other hematopoietic precursors by histiocytes or macrophages observed in the spleen. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Wunderlich M, Stockman C, Devarajan M, Ravishankar N, Sexton C, Kumar AR, Mizukawa B, Mulloy JC
JCI Insight 2016 Sep 22;1(15):e88181. doi: 10.1172/jci.insight.88181. PMID: 27699249Free PMC Article
Ponzoni M, Ferreri AJ, Campo E, Facchetti F, Mazzucchelli L, Yoshino T, Murase T, Pileri SA, Doglioni C, Zucca E, Cavalli F, Nakamura S
J Clin Oncol 2007 Jul 20;25(21):3168-73. Epub 2007 Jun 18 doi: 10.1200/JCO.2006.08.2313. PMID: 17577023
Su IJ, Wang CH, Cheng AL, Chen RL
Leuk Lymphoma 1995 Nov;19(5-6):401-6. doi: 10.3109/10428199509112197. PMID: 8590839

Recent clinical studies

Etiology

Skinner J, Yankey B, Shelton BK
AACN Adv Crit Care 2019 Summer;30(2):151-164. doi: 10.4037/aacnacc2019463. PMID: 31151946
Aronson IK, Worobec SM
Dermatol Ther 2010 Jul-Aug;23(4):389-402. doi: 10.1111/j.1529-8019.2010.01339.x. PMID: 20666826
Masson C, Le Loët X, Lioté F, Renou P, Dubost JJ, Boissier MC, Brithmer L, Brégeon C, Audran M
Rev Rhum Engl Ed 1995 Dec;62(11):748-57. PMID: 8869216
Falk S, Stutte HJ, Frizzera G
Am J Surg Pathol 1991 Nov;15(11):1023-33. PMID: 1928554
Janka GE
Eur J Pediatr 1983 Jun-Jul;140(3):221-30. doi: 10.1007/BF00443367. PMID: 6354720

Diagnosis

Prilutskiy A, Kritselis M, Shevtsov A, Yambayev I, Vadlamudi C, Zhao Q, Kataria Y, Sarosiek SR, Lerner A, Sloan JM, Quillen K, Burks EJ
Am J Clin Pathol 2020 Sep 8;154(4):466-474. doi: 10.1093/ajcp/aqaa124. PMID: 32681166Free PMC Article
Skinner J, Yankey B, Shelton BK
AACN Adv Crit Care 2019 Summer;30(2):151-164. doi: 10.4037/aacnacc2019463. PMID: 31151946
Goto Y, Cheng J, Omachi S, Morimoto A
Parasitol Res 2017 Feb;116(2):457-464. Epub 2016 Nov 7 doi: 10.1007/s00436-016-5313-x. PMID: 27822583
Créput C, Galicier L, Buyse S, Azoulay E
Intensive Care Med 2008 Jul;34(7):1177-87. Epub 2008 Apr 22 doi: 10.1007/s00134-008-1111-y. PMID: 18427781
Janka GE
Eur J Pediatr 1983 Jun-Jul;140(3):221-30. doi: 10.1007/BF00443367. PMID: 6354720

Therapy

Goto Y, Cheng J, Omachi S, Morimoto A
Parasitol Res 2017 Feb;116(2):457-464. Epub 2016 Nov 7 doi: 10.1007/s00436-016-5313-x. PMID: 27822583
Mun JI, Shin SJ, Yu BH, Koo JH, Kim DH, Lee KM, Lee KJ
Korean J Intern Med 2013 May;28(3):352-5. Epub 2013 May 1 doi: 10.3904/kjim.2013.28.3.352. PMID: 23682230Free PMC Article
Al-Talag AH, Mohamed AE, Dafulla MM, Ghandour Z, Al-Karawi MA, Haleem A
Saudi Med J 2000 Oct;21(10):979-82. PMID: 11369969
Shimazaki C, Inaba T, Nakagawa M
Leuk Lymphoma 2000 Jun;38(1-2):121-30. doi: 10.3109/10428190009060325. PMID: 10811454
Janka GE
Eur J Pediatr 1983 Jun-Jul;140(3):221-30. doi: 10.1007/BF00443367. PMID: 6354720

Prognosis

Prilutskiy A, Kritselis M, Shevtsov A, Yambayev I, Vadlamudi C, Zhao Q, Kataria Y, Sarosiek SR, Lerner A, Sloan JM, Quillen K, Burks EJ
Am J Clin Pathol 2020 Sep 8;154(4):466-474. doi: 10.1093/ajcp/aqaa124. PMID: 32681166Free PMC Article
Aronson IK, Worobec SM
Dermatol Ther 2010 Jul-Aug;23(4):389-402. doi: 10.1111/j.1529-8019.2010.01339.x. PMID: 20666826
Créput C, Galicier L, Buyse S, Azoulay E
Intensive Care Med 2008 Jul;34(7):1177-87. Epub 2008 Apr 22 doi: 10.1007/s00134-008-1111-y. PMID: 18427781
Malhotra AK, Bhaskar G, Nanda M, Kabra M, Singh MK, Ramam M
J Am Acad Dermatol 2006 Aug;55(2):337-40. doi: 10.1016/j.jaad.2005.11.1056. PMID: 16844525
Janka GE
Eur J Pediatr 1983 Jun-Jul;140(3):221-30. doi: 10.1007/BF00443367. PMID: 6354720

Clinical prediction guides

Maria NI, Papoin J, Raparia C, Sun Z, Josselsohn R, Lu A, Katerji H, Syeda MM, Polsky D, Paulson R, Kalfa T, Barnes BJ, Zhang W, Blanc L, Davidson A
Life Sci Alliance 2023 Oct;6(10) Epub 2023 Jul 26 doi: 10.26508/lsa.202302241. PMID: 37495396Free PMC Article
Prilutskiy A, Kritselis M, Shevtsov A, Yambayev I, Vadlamudi C, Zhao Q, Kataria Y, Sarosiek SR, Lerner A, Sloan JM, Quillen K, Burks EJ
Am J Clin Pathol 2020 Sep 8;154(4):466-474. doi: 10.1093/ajcp/aqaa124. PMID: 32681166Free PMC Article
Goto Y, Cheng J, Omachi S, Morimoto A
Parasitol Res 2017 Feb;116(2):457-464. Epub 2016 Nov 7 doi: 10.1007/s00436-016-5313-x. PMID: 27822583
Kerl K, Wolf IH, Cerroni L, Wolf P, French LE, Kerl H
Am J Dermatopathol 2015 Jul;37(7):539-43. doi: 10.1097/DAD.0000000000000166. PMID: 25062264
Chan JK
Semin Diagn Pathol 2003 May;20(2):105-20. doi: 10.1016/s0740-2570(03)00013-3. PMID: 12945934

Recent systematic reviews

Satturwar S, Fowkes M, Farver C, Wilson AM, Eccher A, Girolami I, Pujadas E, Bryce C, Salem F, El Jamal SM, Paniz-Mondolfi A, Petersen B, Gordon RE, Reidy J, Fraggetta F, Marshall DA, Pantanowitz L
Am J Surg Pathol 2021 May 1;45(5):587-603. doi: 10.1097/PAS.0000000000001650. PMID: 33481385Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...