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Generalized-onset motor seizure

MedGen UID:
1841580
•Concept ID:
C5779702
•
Sign or Symptom
Synonyms: Generalised onset motor seizure; Generalised-onset motor seizure; Generalized onset motor seizure
 
HPO: HP:0032677

Definition

A generalized motor seizure is a type of generalized-onset seizure with predominantly motor (involving musculature) signs. The motor event could consist of an increase (positive) or decrease (negative) in muscle contraction to produce a movement. [from HPO]

Professional guidelines

PubMed

Clinical characteristics of patients with epilepsy attending primary health care.
Arteaga-Rodríguez C, Menine-Kubis M, Teixeira-Arteaga CB, Hernández-Fustes OJ
Rev Neurol 2022 Jul 1;75(1):7-12. doi: 10.33588/rn.7501.2022036. PMID: 35765823Free PMC Article
Is the differential diagnosis of epilepsy and psychogenic nonepileptic seizures possible by assessing the neutrophil/lymphocyte ratio?
Morkavuk G, Koc G, Leventoglu A
Epilepsy Behav 2021 Mar;116:107736. Epub 2021 Jan 23 doi: 10.1016/j.yebeh.2020.107736. PMID: 33493811
Electroclinical Phenotype-Genotype Homogeneity in Drug-Resistant "Generalized" Tonic-Clonic Seizures of Early Childhood.
Jukkarwala A, Menon RN, Sunesh ER, Radhakrishnan A
Clin EEG Neurosci 2021 Sep;52(5):371-375. Epub 2020 Sep 3 doi: 10.1177/1550059420953735. PMID: 32880473

Recent clinical studies

Etiology

Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial.
Verma N, Maiti R, Mishra BR, Jha M, Jena M, Mishra A
J Neurosci Res 2021 Jun;99(6):1618-1631. Epub 2021 Feb 27 doi: 10.1002/jnr.24820. PMID: 33641195

Diagnosis

Case Report: Thrombotic-Thrombocytopenic Purpura Following Ipilimumab and Nivolumab Combination Immunotherapy for Metastatic Melanoma.
Mullally WJ, Cooke FJ, Crosbie IM, Kumar S, Abernethy VE, Jordan EJ, O'Connor M, Horgan AM, Landers R, Naidoo J, Calvert PM
Front Immunol 2022;13:871217. Epub 2022 Apr 20 doi: 10.3389/fimmu.2022.871217. PMID: 35514990Free PMC Article

Therapy

Case Report: Thrombotic-Thrombocytopenic Purpura Following Ipilimumab and Nivolumab Combination Immunotherapy for Metastatic Melanoma.
Mullally WJ, Cooke FJ, Crosbie IM, Kumar S, Abernethy VE, Jordan EJ, O'Connor M, Horgan AM, Landers R, Naidoo J, Calvert PM
Front Immunol 2022;13:871217. Epub 2022 Apr 20 doi: 10.3389/fimmu.2022.871217. PMID: 35514990Free PMC Article
Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial.
Verma N, Maiti R, Mishra BR, Jha M, Jena M, Mishra A
J Neurosci Res 2021 Jun;99(6):1618-1631. Epub 2021 Feb 27 doi: 10.1002/jnr.24820. PMID: 33641195

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