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Abnormal sperm physiology

MedGen UID:
1841741
Concept ID:
C5826676
Finding
HPO: HP:0034809

Definition

Abnormality of a sperm function including protection of paternal DNA, traversing the female reproductive tract, oocyte localisation, penetration of the zona pellucida, oocyte activation and centriole deposition. [from HPO]

Professional guidelines

PubMed

Krausz C, Navarro-Costa P, Wilke M, Tüttelmann F
Andrology 2024 Mar;12(3):487-504. Epub 2023 Sep 6 doi: 10.1111/andr.13514. PMID: 37674303
Lindsay TJ, Vitrikas KR
Am Fam Physician 2015 Mar 1;91(5):308-14. PMID: 25822387
Krausz C, Hoefsloot L, Simoni M, Tüttelmann F; European Academy of Andrology; European Molecular Genetics Quality Network
Andrology 2014 Jan;2(1):5-19. doi: 10.1111/j.2047-2927.2013.00173.x. PMID: 24357628Free PMC Article

Recent clinical studies

Etiology

Sá R, Ferraz L, Barros A, Sousa M
Genes (Basel) 2023 Mar 4;14(3) doi: 10.3390/genes14030647. PMID: 36980920Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Mikwar M, MacFarlane AJ, Marchetti F
Mutat Res Rev Mutat Res 2020 Jul-Sep;785:108320. Epub 2020 Jul 4 doi: 10.1016/j.mrrev.2020.108320. PMID: 32800274
Cordeiro CN, Bano R, Washington Cross CI, Segars JH
Curr Opin Obstet Gynecol 2017 Jun;29(3):175-179. doi: 10.1097/GCO.0000000000000366. PMID: 28410349
Baird DT, Collins J, Egozcue J, Evers LH, Gianaroli L, Leridon H, Sunde A, Templeton A, Van Steirteghem A, Cohen J, Crosignani PG, Devroey P, Diedrich K, Fauser BC, Fraser L, Glasier A, Liebaers I, Mautone G, Penney G, Tarlatzis B; ESHRE Capri Workshop Group
Hum Reprod Update 2005 May-Jun;11(3):261-76. Epub 2005 Apr 14 doi: 10.1093/humupd/dmi006. PMID: 15831503

Diagnosis

Sá R, Ferraz L, Barros A, Sousa M
Genes (Basel) 2023 Mar 4;14(3) doi: 10.3390/genes14030647. PMID: 36980920Free PMC Article
Vallet-Buisan M, Mecca R, Jones C, Coward K, Yeste M
Hum Reprod Update 2023 Jul 5;29(4):395-433. doi: 10.1093/humupd/dmad006. PMID: 36882116
Kumar N, Singh AK
Biol Reprod 2021 Mar 11;104(3):508-520. doi: 10.1093/biolre/ioaa213. PMID: 33238303
La Vignera S, Vita R
Int J Immunopathol Pharmacol 2018 Jan-Dec;32:2058738418775241. doi: 10.1177/2058738418775241. PMID: 29737216Free PMC Article
Gatimel N, Moreau J, Parinaud J, Léandri RD
Andrology 2017 Sep;5(5):845-862. Epub 2017 Jul 10 doi: 10.1111/andr.12389. PMID: 28692759

Therapy

Jannatifar R, Parivar K, Roodbari NH, Nasr-Esfahani MH
Reprod Biol Endocrinol 2019 Feb 16;17(1):24. doi: 10.1186/s12958-019-0468-9. PMID: 30771790Free PMC Article
Lizarazo AH, McLoughlin M, Vogiatzi MG
Curr Opin Endocrinol Diabetes Obes 2019 Feb;26(1):60-65. doi: 10.1097/MED.0000000000000454. PMID: 30507702
Virtanen HE, Toppari J
Endocrinol Metab Clin North Am 2015 Dec;44(4):751-60. Epub 2015 Sep 10 doi: 10.1016/j.ecl.2015.07.013. PMID: 26568490
Plotton I, Brosse A, Cuzin B, Lejeune H
Ann Endocrinol (Paris) 2014 May;75(2):118-25. Epub 2014 Apr 29 doi: 10.1016/j.ando.2014.04.004. PMID: 24786702
Anderson D, Schmid TE, Baumgartner A
Asian J Androl 2014 Jan-Feb;16(1):81-8. doi: 10.4103/1008-682X.122342. PMID: 24369136Free PMC Article

Prognosis

Sá R, Ferraz L, Barros A, Sousa M
Genes (Basel) 2023 Mar 4;14(3) doi: 10.3390/genes14030647. PMID: 36980920Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031
Fainberg J, Hayden RP, Schlegel PN
Expert Rev Endocrinol Metab 2019 Nov;14(6):369-380. Epub 2019 Oct 7 doi: 10.1080/17446651.2019.1671821. PMID: 31587581
Baird DT, Collins J, Egozcue J, Evers LH, Gianaroli L, Leridon H, Sunde A, Templeton A, Van Steirteghem A, Cohen J, Crosignani PG, Devroey P, Diedrich K, Fauser BC, Fraser L, Glasier A, Liebaers I, Mautone G, Penney G, Tarlatzis B; ESHRE Capri Workshop Group
Hum Reprod Update 2005 May-Jun;11(3):261-76. Epub 2005 Apr 14 doi: 10.1093/humupd/dmi006. PMID: 15831503

Clinical prediction guides

Sá R, Ferraz L, Barros A, Sousa M
Genes (Basel) 2023 Mar 4;14(3) doi: 10.3390/genes14030647. PMID: 36980920Free PMC Article
Gentiluomo M, Luddi A, Cingolani A, Fornili M, Governini L, Lucenteforte E, Baglietto L, Piomboni P, Campa D
Int J Mol Sci 2021 Apr 12;22(8) doi: 10.3390/ijms22083959. PMID: 33921254Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Dam AH, Feenstra I, Westphal JR, Ramos L, van Golde RJ, Kremer JA
Hum Reprod Update 2007 Jan-Feb;13(1):63-75. Epub 2006 Sep 28 doi: 10.1093/humupd/dml047. PMID: 17008355
Baird DT, Collins J, Egozcue J, Evers LH, Gianaroli L, Leridon H, Sunde A, Templeton A, Van Steirteghem A, Cohen J, Crosignani PG, Devroey P, Diedrich K, Fauser BC, Fraser L, Glasier A, Liebaers I, Mautone G, Penney G, Tarlatzis B; ESHRE Capri Workshop Group
Hum Reprod Update 2005 May-Jun;11(3):261-76. Epub 2005 Apr 14 doi: 10.1093/humupd/dmi006. PMID: 15831503

Recent systematic reviews

Cannarella R, Crafa A, Barbagallo F, Lundy SD, La Vignera S, Condorelli RA, Calogero AE
Int J Mol Sci 2023 Apr 13;24(8) doi: 10.3390/ijms24087224. PMID: 37108386Free PMC Article
Houston BJ, Riera-Escamilla A, Wyrwoll MJ, Salas-Huetos A, Xavier MJ, Nagirnaja L, Friedrich C, Conrad DF, Aston KI, Krausz C, Tüttelmann F, O'Bryan MK, Veltman JA, Oud MS
Hum Reprod Update 2021 Dec 21;28(1):15-29. doi: 10.1093/humupd/dmab030. PMID: 34498060Free PMC Article
Simon L, Emery B, Carrell DT
Adv Exp Med Biol 2019;1166:87-105. doi: 10.1007/978-3-030-21664-1_6. PMID: 31301048
Simon L, Emery BR, Carrell DT
Best Pract Res Clin Obstet Gynaecol 2017 Oct;44:38-56. Epub 2017 Aug 2 doi: 10.1016/j.bpobgyn.2017.07.003. PMID: 28935366
Gunes S, Hekim GN, Arslan MA, Asci R
J Assist Reprod Genet 2016 Apr;33(4):441-54. Epub 2016 Feb 11 doi: 10.1007/s10815-016-0663-y. PMID: 26867640Free PMC Article

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