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Multiple eyelid margin cysts

MedGen UID:
1841925
•Concept ID:
C5826791
•
Anatomical Abnormality
Synonym: Multiple eyelid-margin apocrine hidrocystomas
 
HPO: HP:0034946

Definition

Presence of many apocrine hidrocystoma (cysts) on the margins of the eyelids. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple eyelid margin cysts

Conditions with this feature

SchC6pf-Schulz-Passarge syndrome
MedGen UID:
347366
•Concept ID:
C1857069
•
Disease or Syndrome
Schopf-Schulz-Passarge syndrome (SSPS) is an autosomal recessive disorder characterized by a constellation of multiple eyelid cysts, hypodontia, hypotrichosis, palmoplantar hyperkeratosis, and onychodystrophy (summary by Mallaiah and Dickinson, 2001).
See: Condition Record
SchC6pf-Schulz-Passarge syndrome

Recent clinical studies

Etiology

Chalazion: racial risk factors for formation, recurrence, and surgical intervention.
Evans J, Vo KBH, Schmitt M
Can J Ophthalmol 2022 Aug;57(4):242-246. Epub 2021 May 30 doi: 10.1016/j.jcjo.2021.04.023. PMID: 34062122Free PMC Article
Unusual Eyelid Dermal Keratinous Cysts of Pilosebaceous Origin.
Jakobiec FA, Stagner AM, Freitag SK, Yoon MK
Ophthalmic Plast Reconstr Surg 2016 Mar-Apr;32(2):93-7. doi: 10.1097/IOP.0000000000000423. PMID: 25719379
Syringomatous carcinoma of the eyelid and orbit: a clinical and histopathological challenge.
Hoppenreijs VP, Reuser TT, Mooy CM, de Keizer RJ, Mourits MP
Br J Ophthalmol 1997 Aug;81(8):668-72. doi: 10.1136/bjo.81.8.668. PMID: 9349155Free PMC Article

Diagnosis

Chalazion: racial risk factors for formation, recurrence, and surgical intervention.
Evans J, Vo KBH, Schmitt M
Can J Ophthalmol 2022 Aug;57(4):242-246. Epub 2021 May 30 doi: 10.1016/j.jcjo.2021.04.023. PMID: 34062122Free PMC Article
Multiple Eyelid Cysts (Apocrine and Eccrine Hidrocystomas, Trichilemmal Cyst, and Hybrid Cyst) in a Patient With a Prolactinoma.
Ma L, Jakobiec FA, Wolkow N, Dryja TP, Borodic GE
Ophthalmic Plast Reconstr Surg 2018 May/Jun;34(3):e83-e85. doi: 10.1097/IOP.0000000000001069. PMID: 29351118
Syringomatous carcinoma of the eyelid and orbit: a clinical and histopathological challenge.
Hoppenreijs VP, Reuser TT, Mooy CM, de Keizer RJ, Mourits MP
Br J Ophthalmol 1997 Aug;81(8):668-72. doi: 10.1136/bjo.81.8.668. PMID: 9349155Free PMC Article
Multiple bilateral apocrine cystadenomas of the lower eyelids. Light and electron microscopic studies.
Sacks E, Jakobiec FA, McMillan R, Fraunfelder F, Iwamoto T
Ophthalmology 1987 Jan;94(1):65-71. doi: 10.1016/s0161-6420(87)33501-8. PMID: 3561959

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