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Malignant rhabdoid tumor of muscle

MedGen UID:
1842117
•Concept ID:
C5826481
•
Neoplastic Process
HPO: HP:0034562

Definition

A malginant rhabdoid tumor (MRT) originating in muscle tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant rhabdoid tumor of muscle

Professional guidelines

PubMed

SIX1 as a Novel Immunohistochemical Marker in the Differential Diagnosis of Rhabdomyosarcoma.
Ehinger D, Frostberg H, Larsson S, Gisselsson D
Fetal Pediatr Pathol 2023 Oct;42(5):723-734. Epub 2023 May 24 doi: 10.1080/15513815.2023.2214806. PMID: 37224459
Uterine Tumors Resembling Ovarian Sex Cord Tumors: A Clinicopathologic Study of 75 Cases Emphasizing Features Predicting Adverse Outcome and Differential Diagnosis.
Boyraz B, Watkins JC, Young RH, Oliva E
Am J Surg Pathol 2023 Feb 1;47(2):234-247. Epub 2022 Oct 27 doi: 10.1097/PAS.0000000000001981. PMID: 36306239
Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis.
Miettinen M, Fanburg-Smith JC, Virolainen M, Shmookler BM, Fetsch JF
Hum Pathol 1999 Aug;30(8):934-42. doi: 10.1016/s0046-8177(99)90247-2. PMID: 10452506

Recent clinical studies

Etiology

Brain and Spinal Cord Tumors of Embryonic Origin.
Lampros M, Alexiou GA
Adv Exp Med Biol 2023;1405:405-420. doi: 10.1007/978-3-031-23705-8_15. PMID: 37452947
Gynecological lesions in hereditary cancer predisposition syndromes.
Dundr P, Cibula D, Foretová L, Macek M Jr, Kopečková K, Petruželka L, Němejcová K, Bártů M, Hojný J, Hájková N, Jakša R, Janega P, Stružinská I
Cesk Patol 2021 Summer;57(2):96-104. PMID: 34275319
"Inflammatory Leiomyosarcoma" and "Histiocyte-rich Rhabdomyoblastic Tumor": a clinicopathological, immunohistochemical and genetic study of 13 cases, with a proposal for reclassification as "Inflammatory Rhabdomyoblastic Tumor".
Cloutier JM, Charville GW, Mertens F, Sukov W, Fritchie K, Perry KD, Edgar M, Rowsey RA, Folpe AL
Mod Pathol 2021 Apr;34(4):758-769. Epub 2020 Oct 22 doi: 10.1038/s41379-020-00703-8. PMID: 33318583
Cutaneous Malignant Melanoma With Rhabdoid Morphology and Smooth Muscle Differentiation: A Challenging Histopathologic Diagnosis.
Prieto-Torres L, Alegría-Landa V, Llanos C, Córdoba A, Kutzner H, Requena L
Am J Dermatopathol 2017 May;39(5):397-403. doi: 10.1097/DAD.0000000000000792. PMID: 28431412
Primary Intracranial Atypical Teratoid/Rhabdoid Tumors: A Clinicopathologic and Neuroradiologic Study.
Zhao RJ, Wu KY, Zhang JG, Ma YH, Kong LF
J Child Neurol 2015 Jul;30(8):1017-23. Epub 2014 Oct 16 doi: 10.1177/0883073814551795. PMID: 25323739

Diagnosis

Mesenchymal Neoplasms of the Liver.
Papke DJ Jr
Surg Pathol Clin 2023 Sep;16(3):609-634. Epub 2023 Jun 11 doi: 10.1016/j.path.2023.04.013. PMID: 37536892
Morphologic Characteristics and Mutational Analysis of Fumarate Hydratase Deficient Kidney and Smooth Muscle Tumors.
McMurtry V, Mahlow J, Coleman JF, Deftereos G, Jattani R, Bastien RRL, Durtschi J, Jarboe E, Lomo L, Sirohi D
Am J Clin Pathol 2023 Feb 1;159(2):164-171. doi: 10.1093/ajcp/aqac148. PMID: 36495298
Uterine Tumors Resembling Ovarian Sex Cord Tumors: A Clinicopathologic Study of 75 Cases Emphasizing Features Predicting Adverse Outcome and Differential Diagnosis.
Boyraz B, Watkins JC, Young RH, Oliva E
Am J Surg Pathol 2023 Feb 1;47(2):234-247. Epub 2022 Oct 27 doi: 10.1097/PAS.0000000000001981. PMID: 36306239
Extrarenal malignant rhabdoid tumor infiltrating the brachial plexus and spinal canal.
Sant T, Ward M, Shah LM, Mahan M, Peckham ME
Neuroradiol J 2023 Feb;36(1):104-107. Epub 2022 May 9 doi: 10.1177/19714009221098368. PMID: 35534016Free PMC Article
A Review of Effusion Cytomorphology of Small Round Cell Tumors.
Han LM, VandenBussche CJ, Abildtrup M, Chandra A, Vohra P
Acta Cytol 2022;66(4):336-346. Epub 2021 Jul 2 doi: 10.1159/000516497. PMID: 34218227

Therapy

Isolated Pure Malignant Rhabdoid Tumor (MRT) of the Bladder: Case Report and Lessons Learned.
Hecht SL, Walker JP, Treece AL, Cost NG
Urology 2020 Mar;137:164-167. Epub 2019 Nov 14 doi: 10.1016/j.urology.2019.10.023. PMID: 31733273
Adult-onset atypical teratoid/rhabdoid tumor featuring long spindle cells with nuclear palisading and perivascular pseudorosettes.
Horiguchi H, Nakata S, Nobusawa S, Uyama S, Miyamoto T, Ueta H, Fujimoto N, Yokoo H
Neuropathology 2017 Feb;37(1):52-57. Epub 2016 Jun 14 doi: 10.1111/neup.12317. PMID: 27297614
Rhabdomyosarcoma with rhabdoid-like features.
Perez-Ordonez B, Kandel RA, Bell R, Bédard YC
Pathol Res Pract 1998;194(5):357-61. doi: 10.1016/s0344-0338(98)80060-5. PMID: 9651949
Malignant rhabdoid tumor of the orbit.
Gündüz K, Shields JA, Eagle RC Jr, Shields CL, De Potter P, Klombers L
Arch Ophthalmol 1998 Feb;116(2):243-6. doi: 10.1001/archopht.116.2.243. PMID: 9488282
Immunohistochemical study of childhood rhabdomyosarcomas and related neoplasms. Results of an Intergroup Rhabdomyosarcoma study project.
Parham DM, Webber B, Holt H, Williams WK, Maurer H
Cancer 1991 Jun 15;67(12):3072-80. doi: 10.1002/1097-0142(19910615)67:12<3072::aid-cncr2820671223>3.0.co;2-z. PMID: 1710539

Prognosis

Brain and Spinal Cord Tumors of Embryonic Origin.
Lampros M, Alexiou GA
Adv Exp Med Biol 2023;1405:405-420. doi: 10.1007/978-3-031-23705-8_15. PMID: 37452947
Uterine Tumors Resembling Ovarian Sex Cord Tumors: A Clinicopathologic Study of 75 Cases Emphasizing Features Predicting Adverse Outcome and Differential Diagnosis.
Boyraz B, Watkins JC, Young RH, Oliva E
Am J Surg Pathol 2023 Feb 1;47(2):234-247. Epub 2022 Oct 27 doi: 10.1097/PAS.0000000000001981. PMID: 36306239
A Review of Effusion Cytomorphology of Small Round Cell Tumors.
Han LM, VandenBussche CJ, Abildtrup M, Chandra A, Vohra P
Acta Cytol 2022;66(4):336-346. Epub 2021 Jul 2 doi: 10.1159/000516497. PMID: 34218227
Malignant rhabdoid transformation of a longstanding, aggressive, and recurrent orbital angiomyxoma.
Jakobiec FA, Callahan AB, Stagner AM, Lee NG, Rashid A, Mendoza P, Grove A, Freitag SK
Surv Ophthalmol 2015 Mar-Apr;60(2):166-76. Epub 2014 Dec 17 doi: 10.1016/j.survophthal.2014.12.002. PMID: 25595060
Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.
Ishiwata T, Matsuda Y, Naito Z
World J Gastroenterol 2011 Jan 28;17(4):409-18. doi: 10.3748/wjg.v17.i4.409. PMID: 21274370Free PMC Article

Clinical prediction guides

Clinical and Molecular Risk Factors in Extracranial Malignant Rhabdoid Tumors: Toward an Integrated Model of High-Risk Tumors.
Fincke VE, Steinbügl M, Chun HE, Nemes K, Mucha M, Loßner M, Dorn F, Gastberger K, Bühner S, Sill M, Kröncke T, Siebert R, Melchior P, Furtwängler R, Schlesner M, Vokuhl C, Röcken C, Johann PD, Frühwald MC
Clin Cancer Res 2024 Oct 15;30(20):4667-4680. doi: 10.1158/1078-0432.CCR-23-3489. PMID: 39120581
SIX1 as a Novel Immunohistochemical Marker in the Differential Diagnosis of Rhabdomyosarcoma.
Ehinger D, Frostberg H, Larsson S, Gisselsson D
Fetal Pediatr Pathol 2023 Oct;42(5):723-734. Epub 2023 May 24 doi: 10.1080/15513815.2023.2214806. PMID: 37224459
Uterine Tumors Resembling Ovarian Sex Cord Tumors: A Clinicopathologic Study of 75 Cases Emphasizing Features Predicting Adverse Outcome and Differential Diagnosis.
Boyraz B, Watkins JC, Young RH, Oliva E
Am J Surg Pathol 2023 Feb 1;47(2):234-247. Epub 2022 Oct 27 doi: 10.1097/PAS.0000000000001981. PMID: 36306239
"Inflammatory Leiomyosarcoma" and "Histiocyte-rich Rhabdomyoblastic Tumor": a clinicopathological, immunohistochemical and genetic study of 13 cases, with a proposal for reclassification as "Inflammatory Rhabdomyoblastic Tumor".
Cloutier JM, Charville GW, Mertens F, Sukov W, Fritchie K, Perry KD, Edgar M, Rowsey RA, Folpe AL
Mod Pathol 2021 Apr;34(4):758-769. Epub 2020 Oct 22 doi: 10.1038/s41379-020-00703-8. PMID: 33318583
Skeletal muscle-like and rhabdoid cells in uterine leiomyomas.
Parker RL, Young RH, Clement PB
Int J Gynecol Pathol 2005 Oct;24(4):319-25. doi: 10.1097/01.pgp.0000177647.45890.b5. PMID: 16175075

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