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Addictive sedative use

MedGen UID:
1853168
•Concept ID:
C5873006
•
Mental or Behavioral Dysfunction
Synonym: Sedative addiction
 
HPO: HP:5200331

Definition

Misuse and/or abuse of sedative drugs. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAddictive sedative use

Professional guidelines

PubMed

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial.
Bogenschutz MP, Ross S, Bhatt S, Baron T, Forcehimes AA, Laska E, Mennenga SE, O'Donnell K, Owens LT, Podrebarac S, Rotrosen J, Tonigan JS, Worth L
JAMA Psychiatry 2022 Oct 1;79(10):953-962. doi: 10.1001/jamapsychiatry.2022.2096. PMID: 36001306Free PMC Article
Use of Phenobarbital in Alcohol Withdrawal Management - A Retrospective Comparison Study of Phenobarbital and Benzodiazepines for Acute Alcohol Withdrawal Management in General Medical Patients.
Nisavic M, Nejad SH, Isenberg BM, Bajwa EK, Currier P, Wallace PM, Velmahos G, Wilens T
Psychosomatics 2019 Sep-Oct;60(5):458-467. Epub 2019 Feb 14 doi: 10.1016/j.psym.2019.02.002. PMID: 30876654
A History of the Pharmacological Treatment of Bipolar Disorder.
López-Muñoz F, Shen WW, D'Ocon P, Romero A, Álamo C
Int J Mol Sci 2018 Jul 23;19(7) doi: 10.3390/ijms19072143. PMID: 30041458Free PMC Article

Recent clinical studies

Etiology

Benzodiazepines and Related Sedatives.
Peng L, Morford KL, Levander XA
Med Clin North Am 2022 Jan;106(1):113-129. doi: 10.1016/j.mcna.2021.08.012. PMID: 34823725
Safety of Psychotropic Medications During Pregnancy.
Raffi ER, Nonacs R, Cohen LS
Clin Perinatol 2019 Jun;46(2):215-234. Epub 2019 Mar 28 doi: 10.1016/j.clp.2019.02.004. PMID: 31010557
How addictive are gabapentin and pregabalin? A systematic review.
Bonnet U, Scherbaum N
Eur Neuropsychopharmacol 2017 Dec;27(12):1185-1215. Epub 2017 Oct 5 doi: 10.1016/j.euroneuro.2017.08.430. PMID: 28988943
Opioids for low back pain.
Deyo RA, Von Korff M, Duhrkoop D
BMJ 2015 Jan 5;350:g6380. doi: 10.1136/bmj.g6380. PMID: 25561513Free PMC Article
The benzodiazepine withdrawal syndrome.
Pétursson H
Addiction 1994 Nov;89(11):1455-9. doi: 10.1111/j.1360-0443.1994.tb03743.x. PMID: 7841856

Diagnosis

Safety of Psychotropic Medications During Pregnancy.
Raffi ER, Nonacs R, Cohen LS
Clin Perinatol 2019 Jun;46(2):215-234. Epub 2019 Mar 28 doi: 10.1016/j.clp.2019.02.004. PMID: 31010557
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D
J Addict Med 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. PMID: 28777203Free PMC Article
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817
Barbiturates.
Coupey SM
Pediatr Rev 1997 Aug;18(8):260-4; quiz 265. doi: 10.1542/pir.18-8-260. PMID: 9255991
Benzodiazepines: reconsidered.
Miller NS, Gold MS
Adv Alcohol Subst Abuse 1990;8(3-4):67-84. doi: 10.1300/J251v08n03_06. PMID: 1971487

Therapy

Benzodiazepines and Related Sedatives.
Peng L, Morford KL, Levander XA
Med Clin North Am 2022 Jan;106(1):113-129. doi: 10.1016/j.mcna.2021.08.012. PMID: 34823725
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D
J Addict Med 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. PMID: 28777203Free PMC Article
How addictive are gabapentin and pregabalin? A systematic review.
Bonnet U, Scherbaum N
Eur Neuropsychopharmacol 2017 Dec;27(12):1185-1215. Epub 2017 Oct 5 doi: 10.1016/j.euroneuro.2017.08.430. PMID: 28988943
Opioids for low back pain.
Deyo RA, Von Korff M, Duhrkoop D
BMJ 2015 Jan 5;350:g6380. doi: 10.1136/bmj.g6380. PMID: 25561513Free PMC Article
Benzodiazepine harm: how can it be reduced?
Lader M
Br J Clin Pharmacol 2014 Feb;77(2):295-301. doi: 10.1111/j.1365-2125.2012.04418.x. PMID: 22882333Free PMC Article

Prognosis

Inpatient management of GHB/GBL withdrawal.
Delic M
Psychiatr Danub 2019 Sep;31(Suppl 3):354-356. PMID: 31488752
Cyclothymia reloaded: A reappraisal of the most misconceived affective disorder.
Perugi G, Hantouche E, Vannucchi G, Pinto O
J Affect Disord 2015 Sep 1;183:119-33. Epub 2015 May 13 doi: 10.1016/j.jad.2015.05.004. PMID: 26005206
An evidence-based review of insomnia treatment in early recovery.
Kaplan KA, McQuaid J, Primich C, Rosenlicht N
J Addict Med 2014 Nov-Dec;8(6):389-94. doi: 10.1097/ADM.0000000000000052. PMID: 25369938
Phenibut dependence.
Samokhvalov AV, Paton-Gay CL, Balchand K, Rehm J
BMJ Case Rep 2013 Feb 6;2013 doi: 10.1136/bcr-2012-008381. PMID: 23391959Free PMC Article
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817

Clinical prediction guides

A pilot randomized controlled trial of ketamine in Borderline Personality Disorder.
Fineberg SK, Choi EY, Shapiro-Thompson R, Dhaliwal K, Neustadter E, Sakheim M, Null K, Trujillo-Diaz D, Rondeau J, Pittaro GF, Peters JR, Corlett PR, Krystal JH
Neuropsychopharmacology 2023 Jun;48(7):991-999. Epub 2023 Feb 17 doi: 10.1038/s41386-023-01540-4. PMID: 36804489Free PMC Article
Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis.
Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
In Search of a Safe Natural Sleep Aid.
Rao TP, Ozeki M, Juneja LR
J Am Coll Nutr 2015;34(5):436-47. Epub 2015 Mar 11 doi: 10.1080/07315724.2014.926153. PMID: 25759004
Antipsychotics and amotivation.
Fervaha G, Takeuchi H, Lee J, Foussias G, Fletcher PJ, Agid O, Remington G
Neuropsychopharmacology 2015 May;40(6):1539-48. Epub 2015 Jan 8 doi: 10.1038/npp.2015.3. PMID: 25567425Free PMC Article
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817

Recent systematic reviews

SAEM GRACE: Phenobarbital for alcohol withdrawal management in the emergency department: A systematic review of direct evidence.
Punia K, Scott W, Manuja K, Campbell K, Balodis IM, MacKillop J
Acad Emerg Med 2024 May;31(5):481-492. Epub 2023 Sep 2 doi: 10.1111/acem.14788. PMID: 37589203
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials.
Fornaro M, Caiazza C, Solini N, De Prisco M, Billeci M, Vannini M, Shorr R, Caiolo S, Lussignoli M, Siskind D, Pigato G, Barone A, Sambataro F, de Bartolomeis A, Correll CU, Solmi M
Mol Psychiatry 2023 Sep;28(9):3648-3660. Epub 2023 Oct 11 doi: 10.1038/s41380-023-02266-x. PMID: 37821573
Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis.
Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
Benzodiazepines for antipsychotic-induced tardive dyskinesia.
Bergman H, Bhoopathi PS, Soares-Weiser K
Cochrane Database Syst Rev 2018 Jan 20;1(1):CD000205. doi: 10.1002/14651858.CD000205.pub3. PMID: 29352477Free PMC Article
How addictive are gabapentin and pregabalin? A systematic review.
Bonnet U, Scherbaum N
Eur Neuropsychopharmacol 2017 Dec;27(12):1185-1215. Epub 2017 Oct 5 doi: 10.1016/j.euroneuro.2017.08.430. PMID: 28988943

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