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Addictive sedative use

MedGen UID:
1853168
•Concept ID:
C5873006
•
Mental or Behavioral Dysfunction
Synonym: Sedative addiction
 
HPO: HP:5200331

Definition

Misuse and/or abuse of sedative drugs. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAddictive sedative use

Professional guidelines

PubMed

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial.
Bogenschutz MP, Ross S, Bhatt S, Baron T, Forcehimes AA, Laska E, Mennenga SE, O'Donnell K, Owens LT, Podrebarac S, Rotrosen J, Tonigan JS, Worth L
JAMA Psychiatry 2022 Oct 1;79(10):953-962. doi: 10.1001/jamapsychiatry.2022.2096. PMID: 36001306Free PMC Article
Use of Phenobarbital in Alcohol Withdrawal Management - A Retrospective Comparison Study of Phenobarbital and Benzodiazepines for Acute Alcohol Withdrawal Management in General Medical Patients.
Nisavic M, Nejad SH, Isenberg BM, Bajwa EK, Currier P, Wallace PM, Velmahos G, Wilens T
Psychosomatics 2019 Sep-Oct;60(5):458-467. Epub 2019 Feb 14 doi: 10.1016/j.psym.2019.02.002. PMID: 30876654
A History of the Pharmacological Treatment of Bipolar Disorder.
López-Muñoz F, Shen WW, D'Ocon P, Romero A, Álamo C
Int J Mol Sci 2018 Jul 23;19(7) doi: 10.3390/ijms19072143. PMID: 30041458Free PMC Article

Recent clinical studies

Etiology

Reducing the risks when using benzodiazepines to treat insomnia: A public health approach.
Modesto-Lowe V, Chaplin MM, León-Barriera R, Jain L
Cleve Clin J Med 2024 May 1;91(5):293-299. doi: 10.3949/ccjm.91a.23061. PMID: 38692699
Benzodiazepines and Related Sedatives.
Peng L, Morford KL, Levander XA
Med Clin North Am 2022 Jan;106(1):113-129. doi: 10.1016/j.mcna.2021.08.012. PMID: 34823725
Safety of Psychotropic Medications During Pregnancy.
Raffi ER, Nonacs R, Cohen LS
Clin Perinatol 2019 Jun;46(2):215-234. Epub 2019 Mar 28 doi: 10.1016/j.clp.2019.02.004. PMID: 31010557
Non-Benzodiazepine Receptor Agonists for Insomnia.
Becker PM, Somiah M
Sleep Med Clin 2015 Mar;10(1):57-76. Epub 2014 Dec 20 doi: 10.1016/j.jsmc.2014.11.002. PMID: 26055674
Addictions and their familiality in Iceland.
Tyrfingsson T, Thorgeirsson TE, Geller F, Runarsdóttir V, Hansdóttir I, Bjornsdottir G, Wiste AK, Jonsdottir GA, Stefansson H, Gulcher JR, Oskarsson H, Gudbjartsson D, Stefansson K
Ann N Y Acad Sci 2010 Feb;1187:208-17. doi: 10.1111/j.1749-6632.2009.05151.x. PMID: 20201855

Diagnosis

Using sedatives-hypnotics or opioids in older adults: a narrow path.
Davies SJC, Mulsant BH
Int Psychogeriatr 2018 Jul;30(7):925-927. doi: 10.1017/S104161021800087X. PMID: 30040060
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D
J Addict Med 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. PMID: 28777203Free PMC Article
Addictions and their familiality in Iceland.
Tyrfingsson T, Thorgeirsson TE, Geller F, Runarsdóttir V, Hansdóttir I, Bjornsdottir G, Wiste AK, Jonsdottir GA, Stefansson H, Gulcher JR, Oskarsson H, Gudbjartsson D, Stefansson K
Ann N Y Acad Sci 2010 Feb;1187:208-17. doi: 10.1111/j.1749-6632.2009.05151.x. PMID: 20201855
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817
Benzodiazepine dependence.
Petursson H, Lader MH
Br J Addict 1981;76(2):133-45. doi: 10.1111/j.1360-0443.1981.tb00218.x. PMID: 7023521

Therapy

Reducing the risks when using benzodiazepines to treat insomnia: A public health approach.
Modesto-Lowe V, Chaplin MM, León-Barriera R, Jain L
Cleve Clin J Med 2024 May 1;91(5):293-299. doi: 10.3949/ccjm.91a.23061. PMID: 38692699
Benzodiazepines and Related Sedatives.
Peng L, Morford KL, Levander XA
Med Clin North Am 2022 Jan;106(1):113-129. doi: 10.1016/j.mcna.2021.08.012. PMID: 34823725
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D
J Addict Med 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. PMID: 28777203Free PMC Article
Phenibut dependence.
Samokhvalov AV, Paton-Gay CL, Balchand K, Rehm J
BMJ Case Rep 2013 Feb 6;2013 doi: 10.1136/bcr-2012-008381. PMID: 23391959Free PMC Article
Delirium prevention and treatment.
Skrobik Y
Crit Care Clin 2009 Jul;25(3):585-91, x. doi: 10.1016/j.ccc.2009.05.003. PMID: 19576532

Prognosis

An evidence-based review of insomnia treatment in early recovery.
Kaplan KA, McQuaid J, Primich C, Rosenlicht N
J Addict Med 2014 Nov-Dec;8(6):389-94. doi: 10.1097/ADM.0000000000000052. PMID: 25369938
Phenibut dependence.
Samokhvalov AV, Paton-Gay CL, Balchand K, Rehm J
BMJ Case Rep 2013 Feb 6;2013 doi: 10.1136/bcr-2012-008381. PMID: 23391959Free PMC Article
Homeostatic control of neural activity: a Drosophila model for drug tolerance and dependence.
Ghezzi A, Atkinson NS
Int Rev Neurobiol 2011;99:23-50. doi: 10.1016/B978-0-12-387003-2.00002-1. PMID: 21906535Free PMC Article
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817
Addiction to benzodiazepines.
Salzman C
Psychiatr Q 1998 Winter;69(4):251-61. doi: 10.1023/a:1022125929946. PMID: 9793106

Clinical prediction guides

A systems omics-based approach to decode substance use disorders and neuroadaptations.
Veerappa A, Pendyala G, Guda C
Neurosci Biobehav Rev 2021 Nov;130:61-80. Epub 2021 Aug 17 doi: 10.1016/j.neubiorev.2021.08.016. PMID: 34411560Free PMC Article
An evidence-based review of insomnia treatment in early recovery.
Kaplan KA, McQuaid J, Primich C, Rosenlicht N
J Addict Med 2014 Nov-Dec;8(6):389-94. doi: 10.1097/ADM.0000000000000052. PMID: 25369938
Addictions and their familiality in Iceland.
Tyrfingsson T, Thorgeirsson TE, Geller F, Runarsdóttir V, Hansdóttir I, Bjornsdottir G, Wiste AK, Jonsdottir GA, Stefansson H, Gulcher JR, Oskarsson H, Gudbjartsson D, Stefansson K
Ann N Y Acad Sci 2010 Feb;1187:208-17. doi: 10.1111/j.1749-6632.2009.05151.x. PMID: 20201855
Benzodiazepine use, abuse, and dependence.
O'brien CP
J Clin Psychiatry 2005;66 Suppl 2:28-33. PMID: 15762817
Nicotine pharmacodynamics: some unresolved issues.
West RJ
Ciba Found Symp 1990;152:210-9; discussion 219-24. doi: 10.1002/9780470513965.ch12. PMID: 2209255

Recent systematic reviews

Chlormethiazole as a hypnotic in elderly patients: A systematic review and meta-analysis.
Al Juburi M, Cramer H, Schaefer M
J Sleep Res 2024 Apr;33(2):e14018. Epub 2023 Sep 2 doi: 10.1111/jsr.14018. PMID: 37658716
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials.
Fornaro M, Caiazza C, Solini N, De Prisco M, Billeci M, Vannini M, Shorr R, Caiolo S, Lussignoli M, Siskind D, Pigato G, Barone A, Sambataro F, de Bartolomeis A, Correll CU, Solmi M
Mol Psychiatry 2023 Sep;28(9):3648-3660. Epub 2023 Oct 11 doi: 10.1038/s41380-023-02266-x. PMID: 37821573
Clinical Presentations and Treatment of Phenibut Toxicity and Withdrawal: A Systematic Literature Review.
Weleff J, Kovacevich A, Burson J, Nero N, Anand A
J Addict Med 2023 Jul-Aug 01;17(4):407-417. Epub 2023 Feb 3 doi: 10.1097/ADM.0000000000001141. PMID: 37579098
Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis.
Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
How addictive are gabapentin and pregabalin? A systematic review.
Bonnet U, Scherbaum N
Eur Neuropsychopharmacol 2017 Dec;27(12):1185-1215. Epub 2017 Oct 5 doi: 10.1016/j.euroneuro.2017.08.430. PMID: 28988943

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