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Pregnancy Complications, Cardiovascular

MedGen UID:
18613
•Concept ID:
C0032963
•
Disease or Syndrome
Synonyms: Cardiovascular Pregnancy Complication; Cardiovascular Pregnancy Complications; Complication, Cardiovascular Pregnancy; Complications, Cardiovascular Pregnancy; Pregnancies, Cardiovascular Complications; Pregnancy Complication, Cardiovascular; Pregnancy, Cardiovascular Complications

Definition

The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPregnancy Complications, Cardiovascular

Professional guidelines

PubMed

Surgical management of spontaneous coronary artery dissection.
Unal M, Korkut AK, Kosem M, Ertunc V, Ozcan M, Caglar N
Tex Heart Inst J 2008;35(4):402-5. PMID: 19156232Free PMC Article
CLASSIFICATION AND DIFFERENTIAL DIAGNOSIS OF THE MYOCARDIOPATHIES.
FOWLER NO
Prog Cardiovasc Dis 1964 Jul;7:1-16. doi: 10.1016/s0033-0620(64)80027-x. PMID: 14214809
HEART DISEASE AND PREGNANCY. II. "RISK AND MANAGEMENT".
GRIFFITH GC, BOGGS RP
Ariz Med 1964 Jul;21:470-6. PMID: 14182480

Recent clinical studies

Etiology

Peripartum Cardiomyopathy.
Farrell AS, Kuller JA, Goldstein SA, Dotters-Katz SK
Obstet Gynecol Surv 2021 Aug;76(8):485-492. doi: 10.1097/OGX.0000000000000903. PMID: 34449851
Valvular Heart Disease in Pregnancy.
Lewey J, Andrade L, Levine LD
Cardiol Clin 2021 Feb;39(1):151-161. Epub 2020 Nov 2 doi: 10.1016/j.ccl.2020.09.010. PMID: 33222810Free PMC Article
Spontaneous Coronary Artery Dissection: JACC State-of-the-Art Review.
Hayes SN, Tweet MS, Adlam D, Kim ESH, Gulati R, Price JE, Rose CH
J Am Coll Cardiol 2020 Aug 25;76(8):961-984. doi: 10.1016/j.jacc.2020.05.084. PMID: 32819471
Peripartum cardiomyopathy.
Honigberg MC, Givertz MM
BMJ 2019 Jan 30;364:k5287. doi: 10.1136/bmj.k5287. PMID: 30700415
The epidemiology of venous thromboembolism.
Heit JA, Spencer FA, White RH
J Thromb Thrombolysis 2016 Jan;41(1):3-14. doi: 10.1007/s11239-015-1311-6. PMID: 26780736Free PMC Article

Diagnosis

Peripartum Cardiomyopathy.
Farrell AS, Kuller JA, Goldstein SA, Dotters-Katz SK
Obstet Gynecol Surv 2021 Aug;76(8):485-492. doi: 10.1097/OGX.0000000000000903. PMID: 34449851
Peripartum cardiomyopathy.
Honigberg MC, Givertz MM
BMJ 2019 Jan 30;364:k5287. doi: 10.1136/bmj.k5287. PMID: 30700415
Cardiac arrest in pregnancy.
Kikuchi J, Deering S
Semin Perinatol 2018 Feb;42(1):33-38. Epub 2017 Dec 13 doi: 10.1053/j.semperi.2017.11.007. PMID: 29246735
Hypertension and Pregnancy.
Lai C, Coulter SA, Woodruff A
Tex Heart Inst J 2017 Oct;44(5):350-351. Epub 2017 Oct 1 doi: 10.14503/THIJ-17-6359. PMID: 29259508Free PMC Article
Peripartum cardiomyopathy.
Mishra VN, Mishra N, Devanshi
J Assoc Physicians India 2013 Apr;61(4):268-73. PMID: 24482966

Therapy

Pregnancy and Venous Thromboembolism: Risk Factors, Trends, Management, and Mortality.
Alsheef MA, Alabbad AM, Albassam RA, Alarfaj RM, Zaidi ARZ, Al-Arfaj O, Abu-Shaheen A
Biomed Res Int 2020;2020:4071892. Epub 2020 Apr 11 doi: 10.1155/2020/4071892. PMID: 32351991Free PMC Article
Combined diet and exercise interventions for preventing gestational diabetes mellitus.
Shepherd E, Gomersall JC, Tieu J, Han S, Crowther CA, Middleton P
Cochrane Database Syst Rev 2017 Nov 13;11(11):CD010443. doi: 10.1002/14651858.CD010443.pub3. PMID: 29129039Free PMC Article
Interventions for varicose veins and leg oedema in pregnancy.
Smyth RM, Aflaifel N, Bamigboye AA
Cochrane Database Syst Rev 2015 Oct 19;2015(10):CD001066. doi: 10.1002/14651858.CD001066.pub3. PMID: 26477632Free PMC Article
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
Firoz T, Magee LA, MacDonell K, Payne BA, Gordon R, Vidler M, von Dadelszen P; Community Level Interventions for Pre-eclampsia (CLIP) Working Group
BJOG 2014 Sep;121(10):1210-8; discussion 1220. Epub 2014 May 16 doi: 10.1111/1471-0528.12737. PMID: 24832366Free PMC Article
Metformin versus insulin for the treatment of gestational diabetes.
Rowan JA, Hague WM, Gao W, Battin MR, Moore MP; MiG Trial Investigators
N Engl J Med 2008 May 8;358(19):2003-15. doi: 10.1056/NEJMoa0707193. PMID: 18463376

Prognosis

Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC).
Roos-Hesselink J, Baris L, Johnson M, De Backer J, Otto C, Marelli A, Jondeau G, Budts W, Grewal J, Sliwa K, Parsonage W, Maggioni AP, van Hagen I, Vahanian A, Tavazzi L, Elkayam U, Boersma E, Hall R
Eur Heart J 2019 Dec 14;40(47):3848-3855. doi: 10.1093/eurheartj/ehz136. PMID: 30907409
Cardio-Obstetrics.
Davis MB, Walsh MN
Circ Cardiovasc Qual Outcomes 2019 Feb;12(2):e005417. doi: 10.1161/CIRCOUTCOMES.118.005417. PMID: 30773028
Pregnancy and Cardiac Disease.
Roos-Hesselink JW, Stein JI
Rev Esp Cardiol (Engl Ed) 2017 Feb;70(2):78-80. Epub 2016 Sep 16 doi: 10.1016/j.rec.2016.08.002. PMID: 27650860
Hypertension in pregnancy.
Raio L, Bolla D, Baumann M
Curr Opin Cardiol 2015 Jul;30(4):411-5. doi: 10.1097/HCO.0000000000000190. PMID: 26049391
Cardiomyopathy in pregnancy.
Lewey J, Haythe J
Semin Perinatol 2014 Aug;38(5):309-17. Epub 2014 Jun 5 doi: 10.1053/j.semperi.2014.04.021. PMID: 25037522

Clinical prediction guides

Cardio-Obstetrics: A Focused Review.
Misra A, Porras MP, Rajendran A, Contreras J, Scott NS
Curr Cardiol Rep 2023 Sep;25(9):1065-1073. Epub 2023 Aug 4 doi: 10.1007/s11886-023-01928-0. PMID: 37540401
Pregnancy Outcomes in Women With Heart Disease: The CARPREG II Study.
Silversides CK, Grewal J, Mason J, Sermer M, Kiess M, Rychel V, Wald RM, Colman JM, Siu SC
J Am Coll Cardiol 2018 May 29;71(21):2419-2430. doi: 10.1016/j.jacc.2018.02.076. PMID: 29793631
Thrombotic microangiopathies of pregnancy: Differential diagnosis.
Gupta M, Feinberg BB, Burwick RM
Pregnancy Hypertens 2018 Apr;12:29-34. Epub 2018 Feb 16 doi: 10.1016/j.preghy.2018.02.007. PMID: 29674195
The epidemiology of venous thromboembolism.
Heit JA, Spencer FA, White RH
J Thromb Thrombolysis 2016 Jan;41(1):3-14. doi: 10.1007/s11239-015-1311-6. PMID: 26780736Free PMC Article
Heart disease in pregnancy.
Emmanuel Y, Thorne SA
Best Pract Res Clin Obstet Gynaecol 2015 Jul;29(5):579-97. Epub 2015 Apr 16 doi: 10.1016/j.bpobgyn.2015.04.002. PMID: 26026739

Recent systematic reviews

Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.
van de Vusse D, Mian P, Schoenmakers S, Flint RB, Visser W, Allegaert K, Versmissen J
Eur J Clin Pharmacol 2022 Nov;78(11):1763-1776. Epub 2022 Sep 15 doi: 10.1007/s00228-022-03382-3. PMID: 36104450Free PMC Article
Aortic dissection during pregnancy and postpartum.
Meng X, Han J, Wang L, Wu Q
J Card Surg 2021 Jul;36(7):2510-2517. Epub 2021 Apr 29 doi: 10.1111/jocs.15575. PMID: 33928681
Review of Cardiovascular Drugs in Pregnancy.
Kaye AB, Bhakta A, Moseley AD, Rao AK, Arif S, Lichtenstein SJ, Aggarwal NT, Volgman AS, Sanghani RM
J Womens Health (Larchmt) 2019 May;28(5):686-697. Epub 2018 Nov 8 doi: 10.1089/jwh.2018.7145. PMID: 30407107
Interventions for varicose veins and leg oedema in pregnancy.
Smyth RM, Aflaifel N, Bamigboye AA
Cochrane Database Syst Rev 2015 Oct 19;2015(10):CD001066. doi: 10.1002/14651858.CD001066.pub3. PMID: 26477632Free PMC Article
Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis.
Bramham K, Parnell B, Nelson-Piercy C, Seed PT, Poston L, Chappell LC
BMJ 2014 Apr 15;348:g2301. doi: 10.1136/bmj.g2301. PMID: 24735917Free PMC Article

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