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Amniotic fluid embolism

MedGen UID:
8586
Concept ID:
C0013927
Disease or Syndrome
Synonyms: Amniotic Fluid Embolism; Amniotic Fluid Embolisms; Embolism, Amniotic Fluid; Embolisms, Amniotic Fluid
SNOMED CT: Amniotic fluid embolism (17263003); Amniotic fluid embolus (860708004)
 
Monarch Initiative: MONDO:0850046
Orphanet: ORPHA617304

Definition

Acute hypotension or cardiac arrest, acute hypoxia or coagulopathy in the absence of any other potential explanation related to the presence of amniotic fluid or the fetal debris within the maternal vascular system during the antepartum or intrapartum period. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmniotic fluid embolism

Professional guidelines

PubMed

Heavner MS, Cucci MD, Barlow B, Bell CM, Eng CC, Erdman G, Li M, Smith SE, Aldhaeefi M, Thompson Bastin ML, Hawkins WA, Rose C, Lankford A
Pharmacotherapy 2023 Jul;43(7):659-674. Epub 2023 Jun 23 doi: 10.1002/phar.2837. PMID: 37323102
Patient Safety and Quality Committee, Society for Maternal-Fetal Medicine. Electronic address: smfm@smfm.org, Combs CA, Montgomery DM, Toner LE, Dildy GA
Am J Obstet Gynecol 2021 Apr;224(4):B29-B32. Epub 2021 Jan 6 doi: 10.1016/j.ajog.2021.01.001. PMID: 33417901
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Pacheco LD, Saade G, Hankins GD, Clark SL
Am J Obstet Gynecol 2016 Aug;215(2):B16-24. Epub 2016 Mar 14 doi: 10.1016/j.ajog.2016.03.012. PMID: 26987420

Recent clinical studies

Etiology

Hofer S, Blaha J, Collins PW, Ducloy-Bouthors AS, Guasch E, Labate F, Lança F, Nyfløt LT, Steiner K, Van de Velde M
Eur J Anaesthesiol 2023 Jan 1;40(1):29-38. Epub 2022 Sep 22 doi: 10.1097/EJA.0000000000001744. PMID: 36131564Free PMC Article
Mazza GR, Youssefzadeh AC, Klar M, Kunze M, Matsuzaki S, Mandelbaum RS, Ouzounian JG, Matsuo K
JAMA Netw Open 2022 Nov 1;5(11):e2242842. doi: 10.1001/jamanetworkopen.2022.42842. PMID: 36399343Free PMC Article
Coggins AS, Gomez E, Sheffield JS
Obstet Gynecol Clin North Am 2022 Sep;49(3):439-460. doi: 10.1016/j.ogc.2022.02.015. PMID: 36122978
Griffin KM, Oxford-Horrey C, Bourjeily G
Clin Chest Med 2022 Sep;43(3):471-488. doi: 10.1016/j.ccm.2022.04.008. PMID: 36116815Free PMC Article
Wheaton N, Al-Abdullah A, Haertlein T
Emerg Med Clin North Am 2019 May;37(2):287-300. doi: 10.1016/j.emc.2019.01.014. PMID: 30940373

Diagnosis

Bridwell RE, Long B, Montrief T, Gottlieb M
West J Emerg Med 2022 Oct 23;23(6):919-925. doi: 10.5811/westjem.2022.8.57929. PMID: 36409940Free PMC Article
Mazza GR, Youssefzadeh AC, Klar M, Kunze M, Matsuzaki S, Mandelbaum RS, Ouzounian JG, Matsuo K
JAMA Netw Open 2022 Nov 1;5(11):e2242842. doi: 10.1001/jamanetworkopen.2022.42842. PMID: 36399343Free PMC Article
Coggins AS, Gomez E, Sheffield JS
Obstet Gynecol Clin North Am 2022 Sep;49(3):439-460. doi: 10.1016/j.ogc.2022.02.015. PMID: 36122978
Griffin KM, Oxford-Horrey C, Bourjeily G
Clin Chest Med 2022 Sep;43(3):471-488. doi: 10.1016/j.ccm.2022.04.008. PMID: 36116815Free PMC Article
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Pacheco LD, Saade G, Hankins GD, Clark SL
Am J Obstet Gynecol 2016 Aug;215(2):B16-24. Epub 2016 Mar 14 doi: 10.1016/j.ajog.2016.03.012. PMID: 26987420

Therapy

Hofer S, Blaha J, Collins PW, Ducloy-Bouthors AS, Guasch E, Labate F, Lança F, Nyfløt LT, Steiner K, Van de Velde M
Eur J Anaesthesiol 2023 Jan 1;40(1):29-38. Epub 2022 Sep 22 doi: 10.1097/EJA.0000000000001744. PMID: 36131564Free PMC Article
Bridwell RE, Long B, Montrief T, Gottlieb M
West J Emerg Med 2022 Oct 23;23(6):919-925. doi: 10.5811/westjem.2022.8.57929. PMID: 36409940Free PMC Article
Fardelmann KL, Alian AA
Anesthesiol Clin 2020 Mar;38(1):85-105. doi: 10.1016/j.anclin.2019.10.005. PMID: 32008659
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Pacheco LD, Saade G, Hankins GD, Clark SL
Am J Obstet Gynecol 2016 Aug;215(2):B16-24. Epub 2016 Mar 14 doi: 10.1016/j.ajog.2016.03.012. PMID: 26987420
Duarte AG
Clin Obstet Gynecol 2014 Dec;57(4):862-70. doi: 10.1097/GRF.0000000000000067. PMID: 25314088

Prognosis

Mazza GR, Youssefzadeh AC, Klar M, Kunze M, Matsuzaki S, Mandelbaum RS, Ouzounian JG, Matsuo K
JAMA Netw Open 2022 Nov 1;5(11):e2242842. doi: 10.1001/jamanetworkopen.2022.42842. PMID: 36399343Free PMC Article
Coggins AS, Gomez E, Sheffield JS
Obstet Gynecol Clin North Am 2022 Sep;49(3):439-460. doi: 10.1016/j.ogc.2022.02.015. PMID: 36122978
Downes KL, Grantz KL, Shenassa ED
Am J Perinatol 2017 Aug;34(10):935-957. Epub 2017 Mar 22 doi: 10.1055/s-0037-1599149. PMID: 28329897Free PMC Article
Sundin CS, Mazac LB
MCN Am J Matern Child Nurs 2017 Jan/Feb;42(1):29-35. doi: 10.1097/NMC.0000000000000292. PMID: 27755062
Gist RS, Stafford IP, Leibowitz AB, Beilin Y
Anesth Analg 2009 May;108(5):1599-602. doi: 10.1213/ane.0b013e31819e43a4. PMID: 19372342

Clinical prediction guides

Yamashita A, Oda T, Aman M, Wakasa T, Gi T, Ide R, Todo Y, Tamura N, Sato Y, Itoh H, Asada Y
BJOG 2023 Dec;130(13):1685-1696. Epub 2023 May 15 doi: 10.1111/1471-0528.17532. PMID: 37184040
Wiseman D, Simard C, Yang SS, Koolian M, Abenhaim HA, Lipes J
Can J Anaesth 2023 Jan;70(1):151-160. Epub 2022 Oct 28 doi: 10.1007/s12630-022-02343-9. PMID: 36307749
Aissi James S, Klein T, Lebreton G, Nizard J, Chommeloux J, Bréchot N, Pineton de Chambrun M, Hékimian G, Luyt CE, Levy B, Kimmoun A, Combes A, Schmidt M
Crit Care 2022 Apr 7;26(1):96. doi: 10.1186/s13054-022-03969-3. PMID: 35392980Free PMC Article
Schröder L, Hellmund A, Gembruch U, Merz WM
Arch Gynecol Obstet 2020 Apr;301(4):923-929. Epub 2020 Mar 9 doi: 10.1007/s00404-020-05466-w. PMID: 32157417
Goucher H, Wong CA, Patel SK, Toledo P
Anesth Analg 2015 Aug;121(2):465-8. doi: 10.1213/ANE.0000000000000786. PMID: 26197375

Recent systematic reviews

Wiseman D, Simard C, Yang SS, Koolian M, Abenhaim HA, Lipes J
Can J Anaesth 2023 Jan;70(1):151-160. Epub 2022 Oct 28 doi: 10.1007/s12630-022-02343-9. PMID: 36307749
Indraccolo U, Battistoni C, Mastrantonio I, Di Iorio R, Greco P, Indraccolo SR
J Matern Fetal Neonatal Med 2018 Mar;31(5):661-665. Epub 2017 Mar 1 doi: 10.1080/14767058.2017.1293034. PMID: 28282766
Downes KL, Grantz KL, Shenassa ED
Am J Perinatol 2017 Aug;34(10):935-957. Epub 2017 Mar 22 doi: 10.1055/s-0037-1599149. PMID: 28329897Free PMC Article
Frati P, Foldes-Papp Z, Zaami S, Busardo FP
Curr Pharm Biotechnol 2014;14(14):1157-62. doi: 10.2174/1389201015666140430101639. PMID: 24804729
Knight M, Berg C, Brocklehurst P, Kramer M, Lewis G, Oats J, Roberts CL, Spong C, Sullivan E, van Roosmalen J, Zwart J
BMC Pregnancy Childbirth 2012 Feb 10;12:7. doi: 10.1186/1471-2393-12-7. PMID: 22325370Free PMC Article

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