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Short bowel syndrome

MedGen UID:
19966
Concept ID:
C0036992
Disease or Syndrome
Synonyms: Bowel Syndrome, Short; Bowel Syndromes, Short; Short Bowel Syndrome; Short Bowel Syndromes; Syndrome, Short Bowel; Syndromes, Short Bowel
SNOMED CT: Acquired short bowel syndrome (235724004); Post-resection short bowel syndrome (235724004); Short bowel syndrome (26629001); SGS - Short gut syndrome (26629001); Short intestine syndrome (26629001); SBS - Short bowel syndrome (26629001); Short gut syndrome (26629001)
 
Monarch Initiative: MONDO:0015183
Orphanet: ORPHA104008

Definition

An intestinal failure due to either a congenital defect, intestinal infarction or extensive surgical resection of the intestinal tract that results in a functional small intestine of less than 200cm in length and is characterized by diarrhea, nutrient malabsorption, bowel dilation and dysmobility. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVShort bowel syndrome
Follow this link to review classifications for Short bowel syndrome in Orphanet.

Professional guidelines

PubMed

Bering J, DiBaise JK
Nutr Clin Pract 2023 May;38 Suppl 1:S46-S58. doi: 10.1002/ncp.10978. PMID: 37115034
Premkumar MH, Soraisham A, Bagga N, Massieu LA, Maheshwari A
Clin Perinatol 2022 Jun;49(2):557-572. Epub 2022 Apr 21 doi: 10.1016/j.clp.2022.02.016. PMID: 35659103
Billiauws L, Maggiori L, Joly F, Panis Y
J Visc Surg 2018 Sep;155(4):283-291. Epub 2018 Jul 21 doi: 10.1016/j.jviscsurg.2017.12.012. PMID: 30041905

Recent clinical studies

Etiology

Premkumar MH
Clin Perinatol 2022 Jun;49(2):521-536. Epub 2022 Apr 21 doi: 10.1016/j.clp.2022.02.013. PMID: 35659101
Nagelkerke SCJ, Poelgeest MYV, Wessel LM, Mutanen A, Langeveld HR, Hill S, Benninga MA, Tabbers MM, Bakx R; ERNICA Intestinal Failure Working Group
Eur J Pediatr Surg 2022 Aug;32(4):301-309. Epub 2021 Mar 4 doi: 10.1055/s-0041-1725187. PMID: 33663008
Billiauws L, Maggiori L, Joly F, Panis Y
J Visc Surg 2018 Sep;155(4):283-291. Epub 2018 Jul 21 doi: 10.1016/j.jviscsurg.2017.12.012. PMID: 30041905
Winkler MF, Smith CE
JPEN J Parenter Enteral Nutr 2014 May;38(1 Suppl):32S-37S. Epub 2014 Jan 13 doi: 10.1177/0148607113517717. PMID: 24418898
Brumm J, Crim BJ, Scott C, Arms M
AORN J 1995 Jun;61(6):995-1000, 1003-14; quiz 1016-21. doi: 10.1016/s0001-2092(06)63804-0. PMID: 7632058

Diagnosis

Bering J, DiBaise JK
Nutr Clin Pract 2023 May;38 Suppl 1:S46-S58. doi: 10.1002/ncp.10978. PMID: 37115034
Aksan A, Farrag K, Blumenstein I, Schröder O, Dignass AU, Stein J
World J Gastroenterol 2021 Jun 28;27(24):3440-3465. doi: 10.3748/wjg.v27.i24.3440. PMID: 34239262Free PMC Article
Ou J, Courtney CM, Steinberger AE, Tecos ME, Warner BW
Nutrients 2020 Feb 18;12(2) doi: 10.3390/nu12020520. PMID: 32085587Free PMC Article
Clark R, Johnson R
Nurs Clin North Am 2018 Sep;53(3):361-374. Epub 2018 Jul 11 doi: 10.1016/j.cnur.2018.05.001. PMID: 30100002
Billiauws L, Maggiori L, Joly F, Panis Y
J Visc Surg 2018 Sep;155(4):283-291. Epub 2018 Jul 21 doi: 10.1016/j.jviscsurg.2017.12.012. PMID: 30041905

Therapy

Bering J, DiBaise JK
Nutr Clin Pract 2023 May;38 Suppl 1:S46-S58. doi: 10.1002/ncp.10978. PMID: 37115034
Le Berre C, Peyrin-Biroulet L; SPIRIT-IOIBD study group
Gastroenterology 2021 Apr;160(5):1452-1460.e21. Epub 2021 Jan 6 doi: 10.1053/j.gastro.2020.10.065. PMID: 33421515
Massironi S, Cavalcoli F, Rausa E, Invernizzi P, Braga M, Vecchi M
Dig Liver Dis 2020 Mar;52(3):253-261. Epub 2019 Dec 28 doi: 10.1016/j.dld.2019.11.013. PMID: 31892505
Billiauws L, Maggiori L, Joly F, Panis Y
J Visc Surg 2018 Sep;155(4):283-291. Epub 2018 Jul 21 doi: 10.1016/j.jviscsurg.2017.12.012. PMID: 30041905
Pironi L, Arends J, Bozzetti F, Cuerda C, Gillanders L, Jeppesen PB, Joly F, Kelly D, Lal S, Staun M, Szczepanek K, Van Gossum A, Wanten G, Schneider SM; Home Artificial Nutrition & Chronic Intestinal Failure Special Interest Group of ESPEN
Clin Nutr 2016 Apr;35(2):247-307. Epub 2016 Feb 8 doi: 10.1016/j.clnu.2016.01.020. PMID: 26944585

Prognosis

Norsa L, Goulet O, Alberti D, DeKooning B, Domellöf M, Haiden N, Hill S, Indrio F, Kӧglmeier J, Lapillonne A, Luque V, Moltu SJ, Saenz De Pipaon M, Savino F, Verduci E, Bronsky J
J Pediatr Gastroenterol Nutr 2023 Aug 1;77(2):298-314. Epub 2023 May 31 doi: 10.1097/MPG.0000000000003850. PMID: 37256821
Berman L, Moss RL
Semin Fetal Neonatal Med 2011 Jun;16(3):145-50. Epub 2011 Apr 22 doi: 10.1016/j.siny.2011.02.002. PMID: 21514258
Henry MC, Moss RL
Semin Pediatr Surg 2008 May;17(2):98-109. doi: 10.1053/j.sempedsurg.2008.02.005. PMID: 18395659
Thompson JS, Gilroy R, Sudan D
J Gastrointest Surg 2008 Jan;12(1):73-6. Epub 2007 Oct 30 doi: 10.1007/s11605-007-0375-9. PMID: 17968630
Curis E, Crenn P, Cynober L
Curr Opin Clin Nutr Metab Care 2007 Sep;10(5):620-6. doi: 10.1097/MCO.0b013e32829fb38d. PMID: 17693747

Clinical prediction guides

Hashash JG, Elkins J, Lewis JD, Binion DG
Gastroenterology 2024 Mar;166(3):521-532. Epub 2024 Jan 23 doi: 10.1053/j.gastro.2023.11.303. PMID: 38276922
Lederhuber H, Massey LH, Kantola VE, Siddiqui MRS, Sayers AE, McDermott FD, Daniels IR, Smart NJ
Tech Coloproctol 2023 Dec;27(12):1139-1154. Epub 2023 Jun 18 doi: 10.1007/s10151-023-02830-1. PMID: 37330988
Bioletto F, D'Eusebio C, Merlo FD, Aimasso U, Ossola M, Pellegrini M, Ponzo V, Chiarotto A, De Francesco A, Ghigo E, Bo S
Nutrients 2022 Feb 14;14(4) doi: 10.3390/nu14040796. PMID: 35215445Free PMC Article
Krela-Kaźmierczak I, Szymczak A, Łykowska-Szuber L, Eder P, Linke K
Adv Clin Exp Med 2016 Jan-Feb;25(1):185-90. doi: 10.17219/acem/33746. PMID: 26935513
Dufay C, Abdelli A, Le Pennec V, Chiche L
J Visc Surg 2012 Aug;149(4):e239-51. Epub 2012 Jul 15 doi: 10.1016/j.jviscsurg.2012.05.005. PMID: 22796300

Recent systematic reviews

Lederhuber H, Massey LH, Kantola VE, Siddiqui MRS, Sayers AE, McDermott FD, Daniels IR, Smart NJ
Tech Coloproctol 2023 Dec;27(12):1139-1154. Epub 2023 Jun 18 doi: 10.1007/s10151-023-02830-1. PMID: 37330988
Bioletto F, D'Eusebio C, Merlo FD, Aimasso U, Ossola M, Pellegrini M, Ponzo V, Chiarotto A, De Francesco A, Ghigo E, Bo S
Nutrients 2022 Feb 14;14(4) doi: 10.3390/nu14040796. PMID: 35215445Free PMC Article
Ferreira RG, Mendonça CR, Gonçalves Ramos LL, de Abreu Tacon FS, Naves do Amaral W, Ruano R
J Matern Fetal Neonatal Med 2022 Dec;35(25):6199-6212. Epub 2021 Apr 25 doi: 10.1080/14767058.2021.1909563. PMID: 33899664
Hong WB, Tan WK, Law LS, Ong DE, Lo EA
Eur J Drug Metab Pharmacokinet 2021 Jul;46(4):465-478. Epub 2021 Jul 1 doi: 10.1007/s13318-021-00696-y. PMID: 34196913
Le Berre C, Peyrin-Biroulet L; SPIRIT-IOIBD study group
Gastroenterology 2021 Apr;160(5):1452-1460.e21. Epub 2021 Jan 6 doi: 10.1053/j.gastro.2020.10.065. PMID: 33421515

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