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Epilepsy, Partial, Sensory

MedGen UID:
199866
•Concept ID:
C0752322
•
Disease or Syndrome
Synonyms: Epilepsy, Sensory Partial; Focal Seizure Disorder, Sensory; Partial Epilepsy, Sensory; Seizure Disorder, Partial, Sensory; Seizure Disorder, Sensory; Seizure Disorder, Sensory, Focal; Seizure Disorders, Sensory; Sensory Focal Seizure Disorder; Sensory Partial Epilepsy; Sensory Partial Seizure Disorder; Sensory Seizure Disorder; Sensory Seizure Disorders

Definition

A disorder characterized by recurrent focal onset seizures which have sensory (i.e., olfactory, visual, tactile, gustatory, or auditory) manifestations. Partial seizures that feature alterations of consciousness are referred to as complex partial seizures (EPILEPSY, COMPLEX PARTIAL). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpilepsy, Partial, Sensory

Professional guidelines

PubMed

Negative myoclonus. An overview of its clinical features, pathophysiological mechanisms, and management.
Rubboli G, Tassinari CA
Neurophysiol Clin 2006 Sep-Dec;36(5-6):337-43. Epub 2007 Jan 23 doi: 10.1016/j.neucli.2006.12.001. PMID: 17336779
Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation.
Cramer JA, Ben Menachem E, French J
Epilepsy Res 2001 Nov;47(1-2):17-25. doi: 10.1016/s0920-1211(01)00286-8. PMID: 11673017

Recent clinical studies

Etiology

Ictal asystole: case report with review of literature.
Marynissen T, Govers N, Vydt T
Acta Cardiol 2012 Aug;67(4):461-4. doi: 10.1080/ac.67.4.2170689. PMID: 22998002
Comparison of heart rate variability parameters during complex partial seizures and psychogenic nonepileptic seizures.
Ponnusamy A, Marques JL, Reuber M
Epilepsia 2012 Aug;53(8):1314-21. Epub 2012 May 29 doi: 10.1111/j.1528-1167.2012.03518.x. PMID: 22642646
LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Ottman R, Winawer MR, Kalachikov S, Barker-Cummings C, Gilliam TC, Pedley TA, Hauser WA
Neurology 2004 Apr 13;62(7):1120-6. doi: 10.1212/01.wnl.0000120098.39231.6e. PMID: 15079011Free PMC Article
Cerebral hyperperfusion syndrome-a case report and literature review.
Rippy EE, Wolfe JH
Vasc Endovascular Surg 2002 Jul-Aug;36(4):291-5. doi: 10.1177/153857440203600407. PMID: 15599480
Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation.
Cramer JA, Ben Menachem E, French J
Epilepsy Res 2001 Nov;47(1-2):17-25. doi: 10.1016/s0920-1211(01)00286-8. PMID: 11673017

Diagnosis

LGI1 microdeletions are not a frequent cause of partial epilepsy with auditory features (PEAF).
Magini P, Bisulli F, Baldassari S, Stipa C, Naldi I, Licchetta L, Menghi V, Tinuper P, Seri M, Pippucci T
Epilepsy Res 2014 Jul;108(5):972-7. Epub 2014 Mar 26 doi: 10.1016/j.eplepsyres.2014.03.005. PMID: 24721199
Diagnostic value and safety of long-term video-EEG monitoring.
Hui AC, Kwan P, Leung TW, Soo Y, Mok VC, Wong LK
Hong Kong Med J 2007 Jun;13(3):228-30. PMID: 17548912
Idiopathic partial epilepsy with auditory features (IPEAF): a clinical and genetic study of 53 sporadic cases.
Bisulli F, Tinuper P, Avoni P, Striano P, Striano S, d'Orsi G, Vignatelli L, Bagattin A, Scudellaro E, Florindo I, Nobile C, Tassinari CA, Baruzzi A, Michelucci R
Brain 2004 Jun;127(Pt 6):1343-52. Epub 2004 Apr 16 doi: 10.1093/brain/awh151. PMID: 15090473
LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Ottman R, Winawer MR, Kalachikov S, Barker-Cummings C, Gilliam TC, Pedley TA, Hauser WA
Neurology 2004 Apr 13;62(7):1120-6. doi: 10.1212/01.wnl.0000120098.39231.6e. PMID: 15079011Free PMC Article
Auras, seizure focus, and psychiatric disorders.
Manchanda R, Freeland A, Schaefer B, McLachlan RS, Blume WT
Neuropsychiatry Neuropsychol Behav Neurol 2000 Jan;13(1):13-9. PMID: 10645732

Therapy

A genetic locus for sensory epilepsy precipitated by contact with hot water maps to chromosome 9p24.3-p23.
Karan KR, Satishchandra P, Sinha S, Anand A
J Genet 2018 Jun;97(2):391-398. PMID: 29932058
Budget impact analysis of adjunctive therapy with lacosamide for partial-onset epileptic seizures in Belgium.
Simoens S
J Med Econ 2011;14(3):299-304. Epub 2011 Apr 13 doi: 10.3111/13696998.2011.577852. PMID: 21488712
Pregabalin: an antiepileptic agent useful for neuropathic pain.
Blommel ML, Blommel AL
Am J Health Syst Pharm 2007 Jul 15;64(14):1475-82. doi: 10.2146/ajhp060371. PMID: 17617497
Cerebral hyperperfusion syndrome-a case report and literature review.
Rippy EE, Wolfe JH
Vasc Endovascular Surg 2002 Jul-Aug;36(4):291-5. doi: 10.1177/153857440203600407. PMID: 15599480
Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation.
Cramer JA, Ben Menachem E, French J
Epilepsy Res 2001 Nov;47(1-2):17-25. doi: 10.1016/s0920-1211(01)00286-8. PMID: 11673017

Prognosis

Long-term outcome of lesional posterior cortical epilepsy surgery in adults.
Elsharkawy AE, El-Ghandour NM, Oppel F, Pannek H, Schulz R, Hoppe M, Woermann FG, Nayel M, Issa A, Ebner A
J Neurol Neurosurg Psychiatry 2009 Jul;80(7):773-80. Epub 2009 Mar 25 doi: 10.1136/jnnp.2008.164145. PMID: 19324869
Partial seizures due to sclerosis of the right amygdala presenting as panic disorder. On the importance of psychopathological assessment in differential diagnosis.
Picardi A, Di Gennaro G, Meldolesi GN, Grammaldo LG, Esposito V, Quarato PP
Psychopathology 2007;40(3):178-83. Epub 2007 Mar 1 doi: 10.1159/000100365. PMID: 17337938
Idiopathic partial epilepsy with auditory features (IPEAF): a clinical and genetic study of 53 sporadic cases.
Bisulli F, Tinuper P, Avoni P, Striano P, Striano S, d'Orsi G, Vignatelli L, Bagattin A, Scudellaro E, Florindo I, Nobile C, Tassinari CA, Baruzzi A, Michelucci R
Brain 2004 Jun;127(Pt 6):1343-52. Epub 2004 Apr 16 doi: 10.1093/brain/awh151. PMID: 15090473
LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Ottman R, Winawer MR, Kalachikov S, Barker-Cummings C, Gilliam TC, Pedley TA, Hauser WA
Neurology 2004 Apr 13;62(7):1120-6. doi: 10.1212/01.wnl.0000120098.39231.6e. PMID: 15079011Free PMC Article
Epileptic kinetopsia: ictal illusory motion perception.
Laff R, Mesad S, Devinsky O
Neurology 2003 Nov 11;61(9):1262-4. doi: 10.1212/01.wnl.0000090464.03392.9b. PMID: 14610133

Clinical prediction guides

A genetic locus for sensory epilepsy precipitated by contact with hot water maps to chromosome 9p24.3-p23.
Karan KR, Satishchandra P, Sinha S, Anand A
J Genet 2018 Jun;97(2):391-398. PMID: 29932058
Symptoms in focal sensory seizures. Clinical and electroencephalographic features.
Di Bonaventura C, Giallonardo AT, Fattouch J, Manfredi M
Seizure 2005 Jan;14(1):1-9. doi: 10.1016/j.seizure.2004.02.002. PMID: 15642493
LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Ottman R, Winawer MR, Kalachikov S, Barker-Cummings C, Gilliam TC, Pedley TA, Hauser WA
Neurology 2004 Apr 13;62(7):1120-6. doi: 10.1212/01.wnl.0000120098.39231.6e. PMID: 15079011Free PMC Article
Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation.
Cramer JA, Ben Menachem E, French J
Epilepsy Res 2001 Nov;47(1-2):17-25. doi: 10.1016/s0920-1211(01)00286-8. PMID: 11673017
Auras, seizure focus, and psychiatric disorders.
Manchanda R, Freeland A, Schaefer B, McLachlan RS, Blume WT
Neuropsychiatry Neuropsychol Behav Neurol 2000 Jan;13(1):13-9. PMID: 10645732

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