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Refractory Small Lymphocytic Lymphoma

MedGen UID:
208953
•Concept ID:
C0855097
•
Neoplastic Process
Synonyms: B-Cell Small Lymphocytic Lymphoma Refractory; Refractory B-Cell Small Lymphocytic Lymphoma

Definition

B-cell small lymphocytic lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Small Lymphocytic Lymphoma

Professional guidelines

PubMed

Update on the management of relapsed/refractory chronic lymphocytic leukemia.
Bennett R, Seymour JF
Blood Cancer J 2024 Feb 21;14(1):33. doi: 10.1038/s41408-024-01001-1. PMID: 38378673Free PMC Article
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia.
Ottaviano G, Georgiadis C, Gkazi SA, Syed F, Zhan H, Etuk A, Preece R, Chu J, Kubat A, Adams S, Veys P, Vora A, Rao K, Qasim W; TT52 CRISPR-CAR group
Sci Transl Med 2022 Oct 26;14(668):eabq3010. doi: 10.1126/scitranslmed.abq3010. PMID: 36288281
Chronic lymphocytic leukemia: 2020 update on diagnosis, risk stratification and treatment.
Hallek M
Am J Hematol 2019 Nov;94(11):1266-1287. Epub 2019 Oct 4 doi: 10.1002/ajh.25595. PMID: 31364186

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