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Arteriolosclerosis

MedGen UID:
209223
Concept ID:
C0878486
Disease or Syndrome
Synonym: Arterioloscleroses
SNOMED CT: Arteriolosclerosis (17941002)
 
Monarch Initiative: MONDO:0006658

Definition

The thickening of the wall of the small arteries and arterioles. It is caused by deposition of hyaline material in the wall or concentric smooth muscle wall hypertrophy. It results in lumen narrowing and tissue ischemia. [from NCI]

Professional guidelines

PubMed

Charidimou A, Smith EE
Stroke 2024 Apr;55(4):1101-1112. Epub 2024 Mar 11 doi: 10.1161/STROKEAHA.123.044167. PMID: 38465605
Rodrigues MA, Samarasekera N, Lerpiniere C, Humphreys C, McCarron MO, White PM, Nicoll JAR, Sudlow CLM, Cordonnier C, Wardlaw JM, Smith C, Al-Shahi Salman R
Lancet Neurol 2018 Mar;17(3):232-240. Epub 2018 Jan 10 doi: 10.1016/S1474-4422(18)30006-1. PMID: 29331631Free PMC Article
Curri SB, Menchini Fabris F
Boll Chim Farm 1996 May;135(5):316-34. PMID: 8942060

Recent clinical studies

Etiology

Inoue Y, Shue F, Bu G, Kanekiyo T
Mol Neurodegener 2023 Jul 11;18(1):46. doi: 10.1186/s13024-023-00640-5. PMID: 37434208Free PMC Article
Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578Free PMC Article
Chang Wong E, Chang Chui H
Continuum (Minneap Minn) 2022 Jun 1;28(3):750-780. doi: 10.1212/CON.0000000000001124. PMID: 35678401Free PMC Article
Wolters FJ, Ikram MA
Arterioscler Thromb Vasc Biol 2019 Aug;39(8):1542-1549. Epub 2019 Jul 11 doi: 10.1161/ATVBAHA.119.311908. PMID: 31294622
Kapasi A, DeCarli C, Schneider JA
Acta Neuropathol 2017 Aug;134(2):171-186. Epub 2017 May 9 doi: 10.1007/s00401-017-1717-7. PMID: 28488154Free PMC Article

Diagnosis

Hosoki S, Hansra GK, Jayasena T, Poljak A, Mather KA, Catts VS, Rust R, Sagare A, Kovacic JC, Brodtmann A, Wallin A, Zlokovic BV, Ihara M, Sachdev PS
Nat Rev Neurol 2023 Dec;19(12):737-753. Epub 2023 Nov 13 doi: 10.1038/s41582-023-00884-1. PMID: 37957261
Inoue Y, Shue F, Bu G, Kanekiyo T
Mol Neurodegener 2023 Jul 11;18(1):46. doi: 10.1186/s13024-023-00640-5. PMID: 37434208Free PMC Article
Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578Free PMC Article
Chang Wong E, Chang Chui H
Continuum (Minneap Minn) 2022 Jun 1;28(3):750-780. doi: 10.1212/CON.0000000000001124. PMID: 35678401Free PMC Article
Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521

Therapy

Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578Free PMC Article
Li Q, Yang Y, Reis C, Tao T, Li W, Li X, Zhang JH
Cell Transplant 2018 Dec;27(12):1711-1722. Epub 2018 Sep 25 doi: 10.1177/0963689718795148. PMID: 30251566Free PMC Article
Naganuma T, Takemoto Y
Contrib Nephrol 2018;196:22-26. Epub 2018 Jul 24 doi: 10.1159/000485692. PMID: 30041200
Tsivgoulis G, Katsanos AH, Giannopoulos G, Panagopoulou V, Jatuzis D, Lemmens R, Deftereos S, Kelly PJ
Curr Pharm Des 2018;24(6):668-674. doi: 10.2174/1381612824666180116100310. PMID: 29336246
Kleinig TJ
J Clin Neurosci 2013 Jul;20(7):919-27. Epub 2013 May 24 doi: 10.1016/j.jocn.2012.12.002. PMID: 23707603

Prognosis

Chen X, Wang J, Shan Y, Cai W, Liu S, Hu M, Liao S, Huang X, Zhang B, Wang Y, Lu Z
J Neurol 2019 Oct;266(10):2347-2362. Epub 2018 Oct 5 doi: 10.1007/s00415-018-9077-3. PMID: 30291424
Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521
Kapasi A, DeCarli C, Schneider JA
Acta Neuropathol 2017 Aug;134(2):171-186. Epub 2017 May 9 doi: 10.1007/s00401-017-1717-7. PMID: 28488154Free PMC Article
Meyrier A
Nephrol Dial Transplant 2015 Nov;30(11):1833-41. Epub 2014 Dec 8 doi: 10.1093/ndt/gfu366. PMID: 25488894
Johnson RJ, Nakagawa T, Jalal D, Sánchez-Lozada LG, Kang DH, Ritz E
Nephrol Dial Transplant 2013 Sep;28(9):2221-8. Epub 2013 Mar 29 doi: 10.1093/ndt/gft029. PMID: 23543594Free PMC Article

Clinical prediction guides

Blevins BL, Vinters HV, Love S, Wilcock DM, Grinberg LT, Schneider JA, Kalaria RN, Katsumata Y, Gold BT, Wang DJJ, Ma SJ, Shade LMP, Fardo DW, Hartz AMS, Jicha GA, Nelson KB, Magaki SD, Schmitt FA, Teylan MA, Ighodaro ET, Phe P, Abner EL, Cykowski MD, Van Eldik LJ, Nelson PT
Acta Neuropathol 2021 Jan;141(1):1-24. Epub 2020 Oct 24 doi: 10.1007/s00401-020-02235-6. PMID: 33098484Free PMC Article
Wolters FJ, Ikram MA
Arterioscler Thromb Vasc Biol 2019 Aug;39(8):1542-1549. Epub 2019 Jul 11 doi: 10.1161/ATVBAHA.119.311908. PMID: 31294622
Chen X, Wang J, Shan Y, Cai W, Liu S, Hu M, Liao S, Huang X, Zhang B, Wang Y, Lu Z
J Neurol 2019 Oct;266(10):2347-2362. Epub 2018 Oct 5 doi: 10.1007/s00415-018-9077-3. PMID: 30291424
Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521
Johnson RJ, Nakagawa T, Jalal D, Sánchez-Lozada LG, Kang DH, Ritz E
Nephrol Dial Transplant 2013 Sep;28(9):2221-8. Epub 2013 Mar 29 doi: 10.1093/ndt/gft029. PMID: 23543594Free PMC Article

Recent systematic reviews

Xu M, Zhu Y, Song X, Zhong X, Yu X, Wang D, Cheng Y, Tao W, Wu B, Liu M
Transl Stroke Res 2024 Jun;15(3):533-544. Epub 2023 Jun 6 doi: 10.1007/s12975-023-01154-4. PMID: 37280502Free PMC Article

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