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Arteriolosclerosis

MedGen UID:: 209223
•Concept ID:: C0878486
•: Disease or Syndrome

Synonym:	Arterioloscleroses
SNOMED CT:	Arteriolosclerosis (17941002)

Monarch Initiative:	MONDO:0006658

Definition

The thickening of the wall of the small arteries and arterioles. It is caused by deposition of hyaline material in the wall or concentric smooth muscle wall hypertrophy. It results in lumen narrowing and tissue ischemia. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVArteriolosclerosis

Abnormality of the cardiovascular system
- Abnormality of cardiovascular system morphology
  - Abnormal vascular morphology
    - Abnormal blood vessel morphology
      - Abnormal systemic arterial morphology
        Arteriosclerosis
        Arteriolosclerosis
        Hyaline Arteriolosclerosis
        Efferent Arteriolar Hyalinosis

Professional guidelines

PubMed

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study.

Rodrigues MA, Samarasekera N, Lerpiniere C, Humphreys C, McCarron MO, White PM, Nicoll JAR, Sudlow CLM, Cordonnier C, Wardlaw JM, Smith C, Al-Shahi Salman R
Lancet Neurol 2018 Mar;17(3):232-240. Epub 2018 Jan 10 doi: 10.1016/S1474-4422(18)30006-1. PMID: 29331631 Free PMC Article

The contribution of MRI in the differential diagnosis of posterior fossa damage.

Gass A, Filippi M, Grossman RI
J Neurol Sci 2000 Jan 15;172 Suppl 1:S43-9. doi: 10.1016/s0022-510x(99)00278-6. PMID: 10606806

Evidence and results obtained with a new trans-epidermal barrier (T.E.B.) drug in the medical treatment of vascular impotence.

Curri SB, Menchini Fabris F
Boll Chim Farm 1996 May;135(5):316-34. PMID: 8942060

See all (8)

Recent clinical studies

Etiology

Cerebral small vessel disease: Recent advances and future directions.

Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578 Free PMC Article

Vascular Cognitive Impairment and Dementia.

Chang Wong E, Chang Chui H
Continuum (Minneap Minn) 2022 Jun 1;28(3):750-780. doi: 10.1212/CON.0000000000001124. PMID: 35678401 Free PMC Article

Brain arteriolosclerosis.

Blevins BL, Vinters HV, Love S, Wilcock DM, Grinberg LT, Schneider JA, Kalaria RN, Katsumata Y, Gold BT, Wang DJJ, Ma SJ, Shade LMP, Fardo DW, Hartz AMS, Jicha GA, Nelson KB, Magaki SD, Schmitt FA, Teylan MA, Ighodaro ET, Phe P, Abner EL, Cykowski MD, Van Eldik LJ, Nelson PT
Acta Neuropathol 2021 Jan;141(1):1-24. Epub 2020 Oct 24 doi: 10.1007/s00401-020-02235-6. PMID: 33098484 Free PMC Article

Epidemiology of Vascular Dementia.

Wolters FJ, Ikram MA
Arterioscler Thromb Vasc Biol 2019 Aug;39(8):1542-1549. Epub 2019 Jul 11 doi: 10.1161/ATVBAHA.119.311908. PMID: 31294622

Structural and Functional Changes in Human Kidneys with Healthy Aging.

Hommos MS, Glassock RJ, Rule AD
J Am Soc Nephrol 2017 Oct;28(10):2838-2844. Epub 2017 Aug 8 doi: 10.1681/ASN.2017040421. PMID: 28790143 Free PMC Article

See all (236)

Diagnosis

Cerebral small vessel disease: Recent advances and future directions.

Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578 Free PMC Article

Vascular Cognitive Impairment and Dementia.

Chang Wong E, Chang Chui H
Continuum (Minneap Minn) 2022 Jun 1;28(3):750-780. doi: 10.1212/CON.0000000000001124. PMID: 35678401 Free PMC Article

Brain arteriolosclerosis.

The pathology and pathophysiology of vascular dementia.

Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521

White Matter Diseases with Radiologic-Pathologic Correlation.

Sarbu N, Shih RY, Jones RV, Horkayne-Szakaly I, Oleaga L, Smirniotopoulos JG
Radiographics 2016 Sep-Oct;36(5):1426-47. doi: 10.1148/rg.2016160031. PMID: 27618323

See all (158)

Therapy

Cerebral small vessel disease: Recent advances and future directions.

Markus HS, de Leeuw FE
Int J Stroke 2023 Jan;18(1):4-14. doi: 10.1177/17474930221144911. PMID: 36575578 Free PMC Article

Mechanism of herbal medicine on hypertensive nephropathy (Review).

Dong Z, Dai H, Feng Z, Liu W, Gao Y, Liu F, Zhang Z, Zhang N, Dong X, Zhao Q, Zhou X, Du J, Liu B
Mol Med Rep 2021 Apr;23(4) Epub 2021 Feb 4 doi: 10.3892/mmr.2021.11873. PMID: 33537809 Free PMC Article

Cerebral Small Vessel Disease.

Li Q, Yang Y, Reis C, Tao T, Li W, Li X, Zhang JH
Cell Transplant 2018 Dec;27(12):1711-1722. Epub 2018 Sep 25 doi: 10.1177/0963689718795148. PMID: 30251566 Free PMC Article

Asymptomatic Cerebrovascular Disease in Dialysis Patients.

Naganuma T, Takemoto Y
Contrib Nephrol 2018;196:22-26. Epub 2018 Jul 24 doi: 10.1159/000485692. PMID: 30041200

The Role of Colchicine in the Prevention of Cerebrovascular Ischemia.

Tsivgoulis G, Katsanos AH, Giannopoulos G, Panagopoulou V, Jatuzis D, Lemmens R, Deftereos S, Kelly PJ
Curr Pharm Des 2018;24(6):668-674. doi: 10.2174/1381612824666180116100310. PMID: 29336246

See all (65)

Prognosis

COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital.

Thakur KT, Miller EH, Glendinning MD, Al-Dalahmah O, Banu MA, Boehme AK, Boubour AL, Bruce SS, Chong AM, Claassen J, Faust PL, Hargus G, Hickman RA, Jambawalikar S, Khandji AG, Kim CY, Klein RS, Lignelli-Dipple A, Lin CC, Liu Y, Miller ML, Moonis G, Nordvig AS, Overdevest JB, Prust ML, Przedborski S, Roth WH, Soung A, Tanji K, Teich AF, Agalliu D, Uhlemann AC, Goldman JE, Canoll P
Brain 2021 Oct 22;144(9):2696-2708. doi: 10.1093/brain/awab148. PMID: 33856027 Free PMC Article

Cerebral small vessel disease: neuroimaging markers and clinical implication.

Chen X, Wang J, Shan Y, Cai W, Liu S, Hu M, Liao S, Huang X, Zhang B, Wang Y, Lu Z
J Neurol 2019 Oct;266(10):2347-2362. Epub 2018 Oct 5 doi: 10.1007/s00415-018-9077-3. PMID: 30291424

Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa.

Akinyemi RO, Owolabi MO, Ihara M, Damasceno A, Ogunniyi A, Dotchin C, Paddick SM, Ogeng'o J, Walker R, Kalaria RN
Brain Res Bull 2019 Feb;145:97-108. Epub 2018 May 25 doi: 10.1016/j.brainresbull.2018.05.018. PMID: 29807146 Free PMC Article

The pathology and pathophysiology of vascular dementia.

Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521

Uric acid and chronic kidney disease: which is chasing which?

Johnson RJ, Nakagawa T, Jalal D, Sánchez-Lozada LG, Kang DH, Ritz E
Nephrol Dial Transplant 2013 Sep;28(9):2221-8. Epub 2013 Mar 29 doi: 10.1093/ndt/gft029. PMID: 23543594 Free PMC Article

See all (132)

Clinical prediction guides

Brain arteriolosclerosis.

Epidemiology of Vascular Dementia.

Wolters FJ, Ikram MA
Arterioscler Thromb Vasc Biol 2019 Aug;39(8):1542-1549. Epub 2019 Jul 11 doi: 10.1161/ATVBAHA.119.311908. PMID: 31294622

Cerebral small vessel disease: neuroimaging markers and clinical implication.

Chen X, Wang J, Shan Y, Cai W, Liu S, Hu M, Liao S, Huang X, Zhang B, Wang Y, Lu Z
J Neurol 2019 Oct;266(10):2347-2362. Epub 2018 Oct 5 doi: 10.1007/s00415-018-9077-3. PMID: 30291424

The pathology and pathophysiology of vascular dementia.

Kalaria RN
Neuropharmacology 2018 May 15;134(Pt B):226-239. Epub 2017 Dec 19 doi: 10.1016/j.neuropharm.2017.12.030. PMID: 29273521

Uric acid and chronic kidney disease: which is chasing which?

Johnson RJ, Nakagawa T, Jalal D, Sánchez-Lozada LG, Kang DH, Ritz E
Nephrol Dial Transplant 2013 Sep;28(9):2221-8. Epub 2013 Mar 29 doi: 10.1093/ndt/gft029. PMID: 23543594 Free PMC Article

See all (172)

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Arteriolosclerosis

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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