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Stress urinary incontinence

MedGen UID:
22580
•Concept ID:
C0042025
•
Disease or Syndrome
Synonyms: Incontinence, Urinary Stress; Stress Incontinence, Urinary; Urinary Incontinence, Stress; Urinary Stress Incontinence
SNOMED CT: Stress urinary incontinence (22220005); Stress bladder incontinence (22220005); Incontinence when straining (22220005); SI - Stress incontinence (22220005); Urinary stress incontinence (22220005); GSI - Genuine stress incontinence (22220005); Genuine stress incontinence (22220005)
 
HPO: HP:0010992

Definition

Involuntary urine leakage synchronous with exertion, or actions such as sneezing, or coughing. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Stress urinary incontinence

Professional guidelines

PubMed

European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence.
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M, Farag F, Groen J, Karavitakis M, Lapitan MC, Manso M, Arteaga SM, Riogh ANA, O'Connor E, Omar MI, Peyronnet B, Phé V, Sakalis VI, Sihra N, Tzelves L, van Poelgeest-Pomfret ML, van den Bos TWL, van der Vaart H, Harding CK
Eur Urol 2022 Jul;82(1):49-59. Epub 2022 Feb 23 doi: 10.1016/j.eururo.2022.01.045. PMID: 35216856
Management of female stress urinary incontinence: A care pathway and update.
Capobianco G, Madonia M, Morelli S, Dessole F, De Vita D, Cherchi PL, Dessole S
Maturitas 2018 Mar;109:32-38. Epub 2017 Dec 9 doi: 10.1016/j.maturitas.2017.12.008. PMID: 29452779
Stress urinary incontinence in pregnant women: a review of prevalence, pathophysiology, and treatment.
Sangsawang B, Sangsawang N
Int Urogynecol J 2013 Jun;24(6):901-12. Epub 2013 Feb 23 doi: 10.1007/s00192-013-2061-7. PMID: 23436035Free PMC Article

Recent clinical studies

Etiology

The Anatomical Pathogenesis of Stress Urinary Incontinence in Women.
Yang X, Wang X, Gao Z, Li L, Lin H, Wang H, Zhou H, Tian D, Zhang Q, Shen J
Medicina (Kaunas) 2022 Dec 20;59(1) doi: 10.3390/medicina59010005. PMID: 36676629Free PMC Article
The pathophysiology of stress urinary incontinence: a systematic review and meta-analysis.
Falah-Hassani K, Reeves J, Shiri R, Hickling D, McLean L
Int Urogynecol J 2021 Mar;32(3):501-552. Epub 2021 Jan 8 doi: 10.1007/s00192-020-04622-9. PMID: 33416968Free PMC Article
Effect of app-based audio guidance pelvic floor muscle training on treatment of stress urinary incontinence in primiparas: A randomized controlled trial.
Wang X, Xu X, Luo J, Chen Z, Feng S
Int J Nurs Stud 2020 Apr;104:103527. Epub 2020 Jan 21 doi: 10.1016/j.ijnurstu.2020.103527. PMID: 32058140
Obesity and Stress Urinary Incontinence: Impact on Pathophysiology and Treatment.
Fuselier A, Hanberry J, Margaret Lovin J, Gomelsky A
Curr Urol Rep 2018 Feb 22;19(1):10. doi: 10.1007/s11934-018-0762-7. PMID: 29468457
Stress urinary incontinence.
Nygaard IE, Heit M
Obstet Gynecol 2004 Sep;104(3):607-20. doi: 10.1097/01.AOG.0000137874.84862.94. PMID: 15339776

Diagnosis

Stress Incontinence in Women.
Wu JM
N Engl J Med 2021 Jun 24;384(25):2428-2436. doi: 10.1056/NEJMcp1914037. PMID: 34161707
Guideline of guidelines: urinary incontinence in women.
Sussman RD, Syan R, Brucker BM
BJU Int 2020 May;125(5):638-655. Epub 2020 Mar 8 doi: 10.1111/bju.14927. PMID: 31625673
Female Voiding Dysfunction and Urinary Incontinence.
Vo A, Kielb SJ
Med Clin North Am 2018 Mar;102(2):313-324. Epub 2017 Dec 20 doi: 10.1016/j.mcna.2017.10.006. PMID: 29406060
Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence.
Fusco F, Abdel-Fattah M, Chapple CR, Creta M, La Falce S, Waltregny D, Novara G
Eur Urol 2017 Oct;72(4):567-591. Epub 2017 May 4 doi: 10.1016/j.eururo.2017.04.026. PMID: 28479203
Stress urinary incontinence.
Nygaard IE, Heit M
Obstet Gynecol 2004 Sep;104(3):607-20. doi: 10.1097/01.AOG.0000137874.84862.94. PMID: 15339776

Therapy

Single-Incision Mini-Slings for Stress Urinary Incontinence in Women.
Abdel-Fattah M, Cooper D, Davidson T, Kilonzo M, Hossain M, Boyers D, Bhal K, Wardle J, N'Dow J, MacLennan G, Norrie J
N Engl J Med 2022 Mar 31;386(13):1230-1243. doi: 10.1056/NEJMoa2111815. PMID: 35353961
Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women.
Dumoulin C, Cacciari LP, Hay-Smith EJC
Cochrane Database Syst Rev 2018 Oct 4;10(10):CD005654. doi: 10.1002/14651858.CD005654.pub4. PMID: 30288727Free PMC Article
Surgery for women with pelvic organ prolapse with or without stress urinary incontinence.
Baessler K, Christmann-Schmid C, Maher C, Haya N, Crawford TJ, Brown J
Cochrane Database Syst Rev 2018 Aug 19;8(8):CD013108. doi: 10.1002/14651858.CD013108. PMID: 30121956Free PMC Article
Effect of Electroacupuncture on Urinary Leakage Among Women With Stress Urinary Incontinence: A Randomized Clinical Trial.
Liu Z, Liu Y, Xu H, He L, Chen Y, Fu L, Li N, Lu Y, Su T, Sun J, Wang J, Yue Z, Zhang W, Zhao J, Zhou Z, Wu J, Zhou K, Ai Y, Zhou J, Pang R, Wang Y, Qin Z, Yan S, Li H, Luo L, Liu B
JAMA 2017 Jun 27;317(24):2493-2501. doi: 10.1001/jama.2017.7220. PMID: 28655016Free PMC Article
Surgical management of pelvic organ prolapse in women.
Maher C, Feiner B, Baessler K, Schmid C
Cochrane Database Syst Rev 2013 Apr 30;(4):CD004014. doi: 10.1002/14651858.CD004014.pub5. PMID: 23633316

Prognosis

Prevalence, incidence and bothersomeness of urinary incontinence in pregnancy: a systematic review and meta-analysis.
Moossdorff-Steinhauser HFA, Berghmans BCM, Spaanderman MEA, Bols EMJ
Int Urogynecol J 2021 Jul;32(7):1633-1652. Epub 2021 Jan 13 doi: 10.1007/s00192-020-04636-3. PMID: 33439277Free PMC Article
Effect of Electroacupuncture on Urinary Leakage Among Women With Stress Urinary Incontinence: A Randomized Clinical Trial.
Liu Z, Liu Y, Xu H, He L, Chen Y, Fu L, Li N, Lu Y, Su T, Sun J, Wang J, Yue Z, Zhang W, Zhao J, Zhou Z, Wu J, Zhou K, Ai Y, Zhou J, Pang R, Wang Y, Qin Z, Yan S, Li H, Luo L, Liu B
JAMA 2017 Jun 27;317(24):2493-2501. doi: 10.1001/jama.2017.7220. PMID: 28655016Free PMC Article
Post-Sling Urinary Retention in Women.
Malacarne DR, Nitti VW
Curr Urol Rep 2016 Nov;17(11):83. doi: 10.1007/s11934-016-0639-6. PMID: 27678391
Urinary incontinence-pathophysiology and management outline.
Santiagu SK, Arianayagam M, Wang A, Rashid P
Aust Fam Physician 2008 Mar;37(3):106-10. PMID: 18345357
Stress Urinary Incontinence.
McGuire EJ, Lytton B, Pepe V, Kohorn EI
Obstet Gynecol 1976 Mar;47(3):255-64. PMID: 943076

Clinical prediction guides

Male stress urinary incontinence is often underreported.
Wolfe AR, Khouri RK Jr, Bhanvadia RR, Dropkin BM, Joice GA, Sanders SC, Hudak SJ, Morey AF
Can J Urol 2021 Apr;28(2):10589-10594. PMID: 33872555
Surgical Treatment of Male Postprostatectomy Incontinence: Current Concepts.
Kretschmer A, Nitti V
Eur Urol Focus 2017 Oct;3(4-5):364-376. Epub 2017 Nov 23 doi: 10.1016/j.euf.2017.11.007. PMID: 29174616
Clinical risk factors and urodynamic predictors prior to surgical treatment for stress urinary incontinence: a narrative review.
Bing MH, Gimbel H, Greisen S, Paulsen LB, Soerensen HC, Lose G
Int Urogynecol J 2015 Feb;26(2):175-85. Epub 2014 Sep 24 doi: 10.1007/s00192-014-2489-4. PMID: 25248411
Stem cell therapy for stress urinary incontinence: a systematic review in human subjects.
Aref-Adib M, Lamb BW, Lee HB, Akinnawo E, Raza MM, Hughes A, Mehta VS, Odonde RI, Yoong W
Arch Gynecol Obstet 2013 Dec;288(6):1213-21. Epub 2013 Sep 29 doi: 10.1007/s00404-013-3028-0. PMID: 24077813
Posthysterectomy vault prolapse.
Barrington JW, Edwards G
Int Urogynecol J Pelvic Floor Dysfunct 2000;11(4):241-5. doi: 10.1007/s001920070033. PMID: 11005477

Recent systematic reviews

Pelvic Floor Muscle Training for Urinary Incontinence with or without Biofeedback or Electrostimulation in Women: A Systematic Review.
Alouini S, Memic S, Couillandre A
Int J Environ Res Public Health 2022 Feb 27;19(5) doi: 10.3390/ijerph19052789. PMID: 35270480Free PMC Article
European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence.
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M, Farag F, Groen J, Karavitakis M, Lapitan MC, Manso M, Arteaga SM, Riogh ANA, O'Connor E, Omar MI, Peyronnet B, Phé V, Sakalis VI, Sihra N, Tzelves L, van Poelgeest-Pomfret ML, van den Bos TWL, van der Vaart H, Harding CK
Eur Urol 2022 Jul;82(1):49-59. Epub 2022 Feb 23 doi: 10.1016/j.eururo.2022.01.045. PMID: 35216856
Electromyographic Biofeedback for Stress Urinary Incontinence or Pelvic Floor Dysfunction in Women: A Systematic Review and Meta-Analysis.
Wu X, Zheng X, Yi X, Lai P, Lan Y
Adv Ther 2021 Aug;38(8):4163-4177. Epub 2021 Jun 27 doi: 10.1007/s12325-021-01831-6. PMID: 34176082Free PMC Article
The pathophysiology of stress urinary incontinence: a systematic review and meta-analysis.
Falah-Hassani K, Reeves J, Shiri R, Hickling D, McLean L
Int Urogynecol J 2021 Mar;32(3):501-552. Epub 2021 Jan 8 doi: 10.1007/s00192-020-04622-9. PMID: 33416968Free PMC Article
What Pelvic Floor Muscle Training Load is Optimal in Minimizing Urine Loss in Women with Stress Urinary Incontinence? A Systematic Review and Meta-Analysis.
García-Sánchez E, Ávila-Gandía V, López-Román J, Martínez-Rodríguez A, Rubio-Arias JÁ
Int J Environ Res Public Health 2019 Nov 8;16(22) doi: 10.3390/ijerph16224358. PMID: 31717291Free PMC Article

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