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Adult central nervous system mixed germ cell tumor

MedGen UID:
231038
Concept ID:
C1332195
Neoplastic Process
Synonyms: Adult Central Nervous System Mixed Germ Cell Tumor; adult central nervous system mixed germ cell tumor; adult mixed germ cell tumor of central nervous system; adult mixed germ cell tumour of central nervous system; mixed germ cell tumor of central nervous system of adults; mixed germ cell tumour of central nervous system of adults
 
Monarch Initiative: MONDO:0004406

Definition

A mixed germ cell tumor of central nervous system that occurs in an adult. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult central nervous system mixed germ cell tumor

Professional guidelines

PubMed

Demir MK, Yapıcıer O, Kılıc T, Celik S, Oven BB, Ozdamarlar U, Kundak NE, Kanan D, Dincer A, Ertem O, Yakut T, Yılmaz B, Safi S
Curr Med Imaging 2023;19(12):1415-1426. doi: 10.2174/1573405619666230213152949. PMID: 36788686
Yeo KK, Nagabushan S, Dhall G, Abdelbaki MS
Neoplasia 2023 Feb;36:100860. Epub 2022 Dec 13 doi: 10.1016/j.neo.2022.100860. PMID: 36521378Free PMC Article
Hundsberger T, Tonder M, Hottinger A, Brügge D, Roelcke U, Putora PM, Stupp R, Weller M
J Neurooncol 2014 Jun;118(2):321-328. Epub 2014 Apr 16 doi: 10.1007/s11060-014-1434-1. PMID: 24736829

Recent clinical studies

Etiology

Liu J, Lin F, Sun Y, Liu X
Diagn Pathol 2024 Feb 22;19(1):39. doi: 10.1186/s13000-024-01465-6. PMID: 38388383Free PMC Article
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Abdel Razek AAK, Elsebaie NA, Zamora C, Castillo M
J Comput Assist Tomogr 2020 May/Jun;44(3):356-369. doi: 10.1097/RCT.0000000000001010. PMID: 32217897
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780

Diagnosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Viaene AN, Santi M, Hawkins C
Pediatr Dev Pathol 2022 Jan-Feb;25(1):46-58. Epub 2021 Apr 19 doi: 10.1177/10935266211009101. PMID: 33872106
Abdel Razek AAK, Elsebaie NA, Zamora C, Castillo M
J Comput Assist Tomogr 2020 May/Jun;44(3):356-369. doi: 10.1097/RCT.0000000000001010. PMID: 32217897
Slegers RJ, Blumcke I
Acta Neuropathol Commun 2020 Mar 9;8(1):27. doi: 10.1186/s40478-020-00904-x. PMID: 32151273Free PMC Article
Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M
World Neurosurg 2018 Apr;112:18-24. Epub 2018 Jan 8 doi: 10.1016/j.wneu.2018.01.012. PMID: 29325939

Therapy

Moodi F, Khodadadi Shoushtari F, Ghadimi DJ, Valizadeh G, Khormali E, Salari HM, Ohadi MAD, Nilipour Y, Jahanbakhshi A, Rad HS
J Magn Reson Imaging 2024 Sep;60(3):923-938. Epub 2023 Nov 29 doi: 10.1002/jmri.29146. PMID: 38031466
Mizumoto M, Oshiro Y, Pan H, Wang F, Kaste SC, Gajjar A, Chemaitilly W, Merchant TE
Pediatr Blood Cancer 2020 Oct;67(10):e28617. Epub 2020 Jul 26 doi: 10.1002/pbc.28617. PMID: 32715632
Kammerer S, Mueller-Eschner M, Lauer A, Luger AL, Quick-Weller J, Franz K, Harter P, Berkefeld J, Wagner M
Rofo 2018 Oct;190(10):955-966. Epub 2018 Jun 18 doi: 10.1055/a-0576-1028. PMID: 29913520
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Prognosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Viaene AN, Santi M, Hawkins C
Pediatr Dev Pathol 2022 Jan-Feb;25(1):46-58. Epub 2021 Apr 19 doi: 10.1177/10935266211009101. PMID: 33872106
Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M
World Neurosurg 2018 Apr;112:18-24. Epub 2018 Jan 8 doi: 10.1016/j.wneu.2018.01.012. PMID: 29325939
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780

Clinical prediction guides

Lampros MG, Vlachos N, Voulgaris S, Alexiou GA
Childs Nerv Syst 2021 Aug;37(8):2465-2474. Epub 2021 Jun 17 doi: 10.1007/s00381-021-05257-x. PMID: 34137942
Ho CY, Bornhorst M, Almira-Suarez MI, Donev K, Grafe M, Gordish-Dressman H, Rodriguez FJ
J Neuropathol Exp Neurol 2020 Jan 1;79(1):67-73. doi: 10.1093/jnen/nlz115. PMID: 31793986Free PMC Article
Graffeo CS, Perry A, Copeland WR 3rd, Giannini C, Neff BA, Driscoll CL, Link MJ
World Neurosurg 2017 Feb;98:632-643. Epub 2016 Nov 12 doi: 10.1016/j.wneu.2016.11.002. PMID: 27836701
Choudhri AF, Whitehead MT, Siddiqui A, Klimo P Jr, Boop FA
Neuroradiol J 2015 Apr;28(2):209-16. Epub 2015 May 11 doi: 10.1177/1971400915581741. PMID: 25963154Free PMC Article
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920

Recent systematic reviews

Pascual JSG, Khu KJO, Starreveld YP
Neuropsychologia 2023 Jan 28;179:108450. Epub 2022 Dec 16 doi: 10.1016/j.neuropsychologia.2022.108450. PMID: 36529263
Lampros MG, Vlachos N, Voulgaris S, Alexiou GA
Childs Nerv Syst 2021 Aug;37(8):2465-2474. Epub 2021 Jun 17 doi: 10.1007/s00381-021-05257-x. PMID: 34137942
Graffeo CS, Perry A, Copeland WR 3rd, Giannini C, Neff BA, Driscoll CL, Link MJ
World Neurosurg 2017 Feb;98:632-643. Epub 2016 Nov 12 doi: 10.1016/j.wneu.2016.11.002. PMID: 27836701
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262
Englot DJ, Berger MS, Barbaro NM, Chang EF
J Neurosurg 2011 Aug;115(2):240-4. Epub 2011 Apr 29 doi: 10.3171/2011.3.JNS1153. PMID: 21529134

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