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Alcohol-Related Hepatocellular Carcinoma

MedGen UID:
231049
Concept ID:
C1332228
Neoplastic Process

Definition

A hepatocellular carcinoma that develops following alcohol-induced injury of the liver parenchyma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlcohol-Related Hepatocellular Carcinoma

Professional guidelines

PubMed

Vitale A, Cabibbo G, Iavarone M, Viganò L, Pinato DJ, Ponziani FR, Lai Q, Casadei-Gardini A, Celsa C, Galati G, Gambato M, Crocetti L, Renzulli M, Giannini EG, Farinati F, Trevisani F, Cillo U; HCC Special Interest Group of the Italian Association for the Study of the Liver
Lancet Oncol 2023 Jul;24(7):e312-e322. doi: 10.1016/S1470-2045(23)00186-9. PMID: 37414020
Ray G
World J Gastroenterol 2022 Oct 28;28(40):5818-5826. doi: 10.3748/wjg.v28.i40.5818. PMID: 36353204Free PMC Article
Testino G, Leone S, Fagoonee S, Pellicano R
Minerva Med 2018 Dec;109(6):457-471. Epub 2018 Sep 13 doi: 10.23736/S0026-4806.18.05844-5. PMID: 30221911

Recent clinical studies

Etiology

Costentin CE, Minoves M, Kotzki S, Farges O, Goutté N, Decaens T, Bailly S
Liver Int 2022 Jul;42(7):1638-1647. Epub 2022 May 11 doi: 10.1111/liv.15256. PMID: 35324065Free PMC Article
Trépo E, Caruso S, Yang J, Imbeaud S, Couchy G, Bayard Q, Letouzé E, Ganne-Carrié N, Moreno C, Oussalah A, Féray C, Blanc JF, Clément B, Hillon P, Boursier J, Paradis V, Calderaro J, Gnemmi V, Nault JC, Guéant JL, Devière J, Archambeaud I, Vitellius C, Turlin B, Bronowicki JP, Gustot T, Sutton A; GENTHEP Consortium, Ziol M, Nahon P, Zucman-Rossi J
Lancet Oncol 2022 Jan;23(1):161-171. Epub 2021 Dec 11 doi: 10.1016/S1470-2045(21)00603-3. PMID: 34902334
Zhang Y, Zeng F, Zeng M, Han X, Cai L, Zhang J, Weng J, Gao Y
Int J Biol Sci 2021;17(13):3554-3572. Epub 2021 Aug 14 doi: 10.7150/ijbs.62168. PMID: 34512165Free PMC Article
Kumar R, Goh BG, Kam JW, Chang PE, Tan CK
Clin Mol Hepatol 2020 Apr;26(2):196-208. Epub 2020 Jan 9 doi: 10.3350/cmh.2019.0012. PMID: 31914720Free PMC Article
Nahon P, Nault JC
Liver Int 2017 Nov;37(11):1591-1601. Epub 2017 Apr 11 doi: 10.1111/liv.13419. PMID: 28296015

Diagnosis

Costentin CE, Minoves M, Kotzki S, Farges O, Goutté N, Decaens T, Bailly S
Liver Int 2022 Jul;42(7):1638-1647. Epub 2022 May 11 doi: 10.1111/liv.15256. PMID: 35324065Free PMC Article
Trépo E, Caruso S, Yang J, Imbeaud S, Couchy G, Bayard Q, Letouzé E, Ganne-Carrié N, Moreno C, Oussalah A, Féray C, Blanc JF, Clément B, Hillon P, Boursier J, Paradis V, Calderaro J, Gnemmi V, Nault JC, Guéant JL, Devière J, Archambeaud I, Vitellius C, Turlin B, Bronowicki JP, Gustot T, Sutton A; GENTHEP Consortium, Ziol M, Nahon P, Zucman-Rossi J
Lancet Oncol 2022 Jan;23(1):161-171. Epub 2021 Dec 11 doi: 10.1016/S1470-2045(21)00603-3. PMID: 34902334
Pan Y, Han G
Comput Math Methods Med 2021;2021:9752534. Epub 2021 Nov 18 doi: 10.1155/2021/9752534. PMID: 34840599Free PMC Article
Zhang Y, Zeng F, Zeng M, Han X, Cai L, Zhang J, Weng J, Gao Y
Int J Biol Sci 2021;17(13):3554-3572. Epub 2021 Aug 14 doi: 10.7150/ijbs.62168. PMID: 34512165Free PMC Article
Kumar R, Goh BG, Kam JW, Chang PE, Tan CK
Clin Mol Hepatol 2020 Apr;26(2):196-208. Epub 2020 Jan 9 doi: 10.3350/cmh.2019.0012. PMID: 31914720Free PMC Article

Therapy

Zhang Y, Zeng F, Zeng M, Han X, Cai L, Zhang J, Weng J, Gao Y
Int J Biol Sci 2021;17(13):3554-3572. Epub 2021 Aug 14 doi: 10.7150/ijbs.62168. PMID: 34512165Free PMC Article
Shi J, Song S, Li S, Zhang K, Lan Y, Li Y
Cancer Med 2021 May;10(10):3346-3357. Epub 2021 May 1 doi: 10.1002/cam4.3832. PMID: 33932127Free PMC Article
Luo Y, Ye J, Wei J, Zhang J, Li Y
Mol Med Rep 2020 Aug;22(2):997-1007. Epub 2020 May 22 doi: 10.3892/mmr.2020.11179. PMID: 32468063Free PMC Article
Kikuchi M, Horie Y, Ebinuma H, Taniki N, Nakamoto N, Kanai T
Nihon Arukoru Yakubutsu Igakkai Zasshi 2015 Oct;50(5):222-34. PMID: 26946783
Yin H, Lin Z, Nie S, Wu J, Tan Z, Zhu J, Dai J, Feng Z, Marrero J, Lubman DM
J Proteome Res 2014 Jun 6;13(6):2887-96. Epub 2014 May 15 doi: 10.1021/pr500043k. PMID: 24799124Free PMC Article

Prognosis

Donati A, Henrion J, Regnier M, Deltenre P, Marot A
Clin Res Hepatol Gastroenterol 2023 Dec;47(10):102225. Epub 2023 Oct 12 doi: 10.1016/j.clinre.2023.102225. PMID: 37838325
Costentin CE, Minoves M, Kotzki S, Farges O, Goutté N, Decaens T, Bailly S
Liver Int 2022 Jul;42(7):1638-1647. Epub 2022 May 11 doi: 10.1111/liv.15256. PMID: 35324065Free PMC Article
Zhang Y, Zeng F, Zeng M, Han X, Cai L, Zhang J, Weng J, Gao Y
Int J Biol Sci 2021;17(13):3554-3572. Epub 2021 Aug 14 doi: 10.7150/ijbs.62168. PMID: 34512165Free PMC Article
Luo Y, Ye J, Wei J, Zhang J, Li Y
Mol Med Rep 2020 Aug;22(2):997-1007. Epub 2020 May 22 doi: 10.3892/mmr.2020.11179. PMID: 32468063Free PMC Article
Shin J, Yu JH, Jin YJ, Chae MH, Yoon CH, Lee JW
Medicine (Baltimore) 2019 Nov;98(47):e18020. doi: 10.1097/MD.0000000000018020. PMID: 31764818Free PMC Article

Clinical prediction guides

Trépo E, Caruso S, Yang J, Imbeaud S, Couchy G, Bayard Q, Letouzé E, Ganne-Carrié N, Moreno C, Oussalah A, Féray C, Blanc JF, Clément B, Hillon P, Boursier J, Paradis V, Calderaro J, Gnemmi V, Nault JC, Guéant JL, Devière J, Archambeaud I, Vitellius C, Turlin B, Bronowicki JP, Gustot T, Sutton A; GENTHEP Consortium, Ziol M, Nahon P, Zucman-Rossi J
Lancet Oncol 2022 Jan;23(1):161-171. Epub 2021 Dec 11 doi: 10.1016/S1470-2045(21)00603-3. PMID: 34902334
Luo Y, Ye J, Wei J, Zhang J, Li Y
Mol Med Rep 2020 Aug;22(2):997-1007. Epub 2020 May 22 doi: 10.3892/mmr.2020.11179. PMID: 32468063Free PMC Article
Kumar R, Goh BG, Kam JW, Chang PE, Tan CK
Clin Mol Hepatol 2020 Apr;26(2):196-208. Epub 2020 Jan 9 doi: 10.3350/cmh.2019.0012. PMID: 31914720Free PMC Article
Shin J, Yu JH, Jin YJ, Chae MH, Yoon CH, Lee JW
Medicine (Baltimore) 2019 Nov;98(47):e18020. doi: 10.1097/MD.0000000000018020. PMID: 31764818Free PMC Article
Nahon P, Nault JC
Liver Int 2017 Nov;37(11):1591-1601. Epub 2017 Apr 11 doi: 10.1111/liv.13419. PMID: 28296015

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