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Behavior disorder

MedGen UID:
520
Concept ID:
C0004930
Mental or Behavioral Dysfunction
Synonyms: behavioral disorder; MAOA-Related Behavior Disorders; SLC6A4-Related Behavior Disorders

Definition

A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBehavior disorder

Professional guidelines

PubMed

Armstrong MJ, Okun MS
JAMA 2020 Feb 11;323(6):548-560. doi: 10.1001/jama.2019.22360. PMID: 32044947
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K
Neurology 2017 Jul 4;89(1):88-100. Epub 2017 Jun 7 doi: 10.1212/WNL.0000000000004058. PMID: 28592453Free PMC Article
Connolly BS, Lang AE
JAMA 2014 Apr 23-30;311(16):1670-83. doi: 10.1001/jama.2014.3654. PMID: 24756517

Recent clinical studies

Etiology

Malkani R
Continuum (Minneap Minn) 2023 Aug 1;29(4):1092-1116. doi: 10.1212/CON.0000000000001293. PMID: 37590824
Hu MT
Neurobiol Dis 2020 Sep;143:104996. Epub 2020 Jun 26 doi: 10.1016/j.nbd.2020.104996. PMID: 32599063
Proserpio P, Terzaghi M, Manni R, Nobili L
Sleep Med Clin 2020 Jun;15(2):289-300. doi: 10.1016/j.jsmc.2020.02.014. PMID: 32386702
Šonka K
Cas Lek Cesk 2019 Winter;158(7-8):318-320. PMID: 31996001
Stiasny-Kolster K, Mayer G, Schäfer S, Möller JC, Heinzel-Gutenbrunner M, Oertel WH
Mov Disord 2007 Dec;22(16):2386-93. doi: 10.1002/mds.21740. PMID: 17894337

Diagnosis

Bisaglia M
Int J Mol Sci 2022 Dec 20;24(1) doi: 10.3390/ijms24010042. PMID: 36613486Free PMC Article
Szûcs A, Mutti C, Papp A, Halász P, Parrino L
Ideggyogy Sz 2022 May 30;75(5-06):171-182. doi: 10.18071/isz.75.0171. PMID: 35819343
Hu MT
Neurobiol Dis 2020 Sep;143:104996. Epub 2020 Jun 26 doi: 10.1016/j.nbd.2020.104996. PMID: 32599063
Shenker JI, Singh G
Mo Med 2017 Jul-Aug;114(4):311-315. PMID: 30228618Free PMC Article
St Louis EK, Boeve BF
Mayo Clin Proc 2017 Nov;92(11):1723-1736. Epub 2017 Nov 1 doi: 10.1016/j.mayocp.2017.09.007. PMID: 29101940Free PMC Article

Therapy

Kolla BP, Hayes L, Cox C, Eatwell L, Deyo-Svendsen M, Mansukhani MP
J Prim Care Community Health 2022 Jan-Dec;13:21501319221081277. doi: 10.1177/21501319221081277. PMID: 35459406Free PMC Article
Seppi K, Ray Chaudhuri K, Coelho M, Fox SH, Katzenschlager R, Perez Lloret S, Weintraub D, Sampaio C; the collaborators of the Parkinson's Disease Update on Non-Motor Symptoms Study Group on behalf of the Movement Disorders Society Evidence-Based Medicine Committee
Mov Disord 2019 Feb;34(2):180-198. Epub 2019 Jan 17 doi: 10.1002/mds.27602. PMID: 30653247Free PMC Article
Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B
Nat Rev Dis Primers 2018 Aug 30;4(1):19. doi: 10.1038/s41572-018-0016-5. PMID: 30166532
Wichniak A, Wierzbicka A, Walęcka M, Jernajczyk W
Curr Psychiatry Rep 2017 Aug 9;19(9):63. doi: 10.1007/s11920-017-0816-4. PMID: 28791566Free PMC Article
Connolly BS, Lang AE
JAMA 2014 Apr 23-30;311(16):1670-83. doi: 10.1001/jama.2014.3654. PMID: 24756517

Prognosis

Borghammer P
J Neural Transm (Vienna) 2023 Jun;130(6):737-753. Epub 2023 Apr 16 doi: 10.1007/s00702-023-02633-6. PMID: 37062013
Howell M, Avidan AY, Foldvary-Schaefer N, Malkani RG, During EH, Roland JP, McCarter SJ, Zak RS, Carandang G, Kazmi U, Ramar K
J Clin Sleep Med 2023 Apr 1;19(4):759-768. doi: 10.5664/jcsm.10424. PMID: 36515157Free PMC Article
Miglis MG, Adler CH, Antelmi E, Arnaldi D, Baldelli L, Boeve BF, Cesari M, Dall'Antonia I, Diederich NJ, Doppler K, Dušek P, Ferri R, Gagnon JF, Gan-Or Z, Hermann W, Högl B, Hu MT, Iranzo A, Janzen A, Kuzkina A, Lee JY, Leenders KL, Lewis SJG, Liguori C, Liu J, Lo C, Ehgoetz Martens KA, Nepozitek J, Plazzi G, Provini F, Puligheddu M, Rolinski M, Rusz J, Stefani A, Summers RLS, Yoo D, Zitser J, Oertel WH
Lancet Neurol 2021 Aug;20(8):671-684. doi: 10.1016/S1474-4422(21)00176-9. PMID: 34302789Free PMC Article
De Pablo-Fernández E, Lees AJ, Holton JL, Warner TT
JAMA Neurol 2019 Apr 1;76(4):470-479. doi: 10.1001/jamaneurol.2018.4377. PMID: 30640364Free PMC Article
St Louis EK, Boeve BF
Mayo Clin Proc 2017 Nov;92(11):1723-1736. Epub 2017 Nov 1 doi: 10.1016/j.mayocp.2017.09.007. PMID: 29101940Free PMC Article

Clinical prediction guides

Sobreira-Neto MA, Stelzer FG, Gitaí LLG, Alves RC, Eckeli AL, Schenck CH
Arq Neuropsiquiatr 2023 Dec;81(12):1179-1194. Epub 2023 Dec 29 doi: 10.1055/s-0043-1777111. PMID: 38157884Free PMC Article
Feuerstein JS, Amara A
Curr Neurol Neurosci Rep 2023 Nov;23(11):727-734. Epub 2023 Oct 13 doi: 10.1007/s11910-023-01310-1. PMID: 37831394
Reichmann H
Neurosci Bull 2017 Oct;33(5):526-534. Epub 2017 Aug 3 doi: 10.1007/s12264-017-0159-5. PMID: 28776303Free PMC Article
Fereshtehnejad SM, Zeighami Y, Dagher A, Postuma RB
Brain 2017 Jul 1;140(7):1959-1976. doi: 10.1093/brain/awx118. PMID: 28549077
Stiasny-Kolster K, Mayer G, Schäfer S, Möller JC, Heinzel-Gutenbrunner M, Oertel WH
Mov Disord 2007 Dec;22(16):2386-93. doi: 10.1002/mds.21740. PMID: 17894337

Recent systematic reviews

Li X, Zong Q, Liu L, Liu Y, Shen Y, Tang X, Wing YK, Li SX, Zhou J
Sleep Med Rev 2023 Oct;71:101810. Epub 2023 Jun 26 doi: 10.1016/j.smrv.2023.101810. PMID: 37422999
Grant Weinandy JT, Lee B, Hoagland KC, Grubbs JB, Bőthe B
J Sex Res 2023 May;60(4):545-557. Epub 2022 Apr 28 doi: 10.1080/00224499.2022.2066616. PMID: 35482896
Kuang B, Li D, Lobbezoo F, de Vries R, Hilgevoord A, de Vries N, Huynh N, Lavigne G, Aarab G
Sleep Med 2022 Jan;89:31-47. Epub 2021 Nov 19 doi: 10.1016/j.sleep.2021.11.008. PMID: 34879286
Büttner-Teleagă A, Kim YT, Osel T, Richter K
Int J Environ Res Public Health 2021 Nov 7;18(21) doi: 10.3390/ijerph182111696. PMID: 34770209Free PMC Article
Cicero CE, Giuliano L, Luna J, Zappia M, Preux PM, Nicoletti A
Sleep 2021 Jun 11;44(6) doi: 10.1093/sleep/zsaa294. PMID: 33388771

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