U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Non-proliferative fibrocystic change of the breast

MedGen UID:
231966
•Concept ID:
C1332628
•
Disease or Syndrome
Synonyms: Breast Fibrocystic Change, Non-Proliferative Type; breast fibrocystic change, non-proliferative type; Non-Proliferative Fibrocystic Change; non-proliferative fibrocystic change; Non-Proliferative Fibrocystic Change of Breast; non-proliferative fibrocystic change of breast; Non-Proliferative Fibrocystic Change of the Breast; non-proliferative fibrocystic change of the breast
 
Monarch Initiative: MONDO:0003724

Definition

Breast fibrocystic change characterized by the absence of epithelial cell hyperplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-proliferative fibrocystic change of the breast

Professional guidelines

PubMed

Differences in breast cancer risk after benign breast disease by type of screening diagnosis.
Louro J, Román M, Posso M, Comerma L, Vidal C, Saladié F, Alcantara R, Sanchez M, Quintana MJ, Del Riego J, Ferrer J, Peñalva L, Bargalló X, Prieto M, Sala M, Castells X
Breast 2020 Dec;54:343-348. Epub 2020 Oct 3 doi: 10.1016/j.breast.2020.09.005. PMID: 33023825Free PMC Article

Recent clinical studies

Etiology

Differences in breast cancer risk after benign breast disease by type of screening diagnosis.
Louro J, Román M, Posso M, Comerma L, Vidal C, Saladié F, Alcantara R, Sanchez M, Quintana MJ, Del Riego J, Ferrer J, Peñalva L, Bargalló X, Prieto M, Sala M, Castells X
Breast 2020 Dec;54:343-348. Epub 2020 Oct 3 doi: 10.1016/j.breast.2020.09.005. PMID: 33023825Free PMC Article
P53 Expression in benign Breast Disease Development: A Systematic Review.
Costa RSS, Silva IFD
Asian Pac J Cancer Prev 2020 Sep 1;21(9):2485-2491. doi: 10.31557/APJCP.2020.21.9.2485. PMID: 32986343Free PMC Article
COMPARISONS BETWEEN THE NON-PROLIFERATIVE AND PROLIFERATIVE THERAPY IN FIBROCYSTIC MASTOSIS.
Carauleanu A, Socolov R, Rugina V, Gabia O, Carauleanu DM, Lupascu IA, Socolov D
Rev Med Chir Soc Med Nat Iasi 2016 Apr-Jun;120(2):321-7. PMID: 27483712
Benign breast disease and the risk of breast cancer in the next 15 years.
Socolov D, Anghelache I, Ilea C, Socolov R, Carauleanu A
Rev Med Chir Soc Med Nat Iasi 2015 Jan-Mar;119(1):135-40. PMID: 25970956
Benign proliferative disorders of the breast.
Ahn HJ, Cho NH, Yang WI, Choi IJ
Yonsei Med J 1990 Jun;31(2):168-73. doi: 10.3349/ymj.1990.31.2.168. PMID: 2219974

Diagnosis

Differences in breast cancer risk after benign breast disease by type of screening diagnosis.
Louro J, Román M, Posso M, Comerma L, Vidal C, Saladié F, Alcantara R, Sanchez M, Quintana MJ, Del Riego J, Ferrer J, Peñalva L, Bargalló X, Prieto M, Sala M, Castells X
Breast 2020 Dec;54:343-348. Epub 2020 Oct 3 doi: 10.1016/j.breast.2020.09.005. PMID: 33023825Free PMC Article
Benign breast disease and the risk of breast cancer in the next 15 years.
Socolov D, Anghelache I, Ilea C, Socolov R, Carauleanu A
Rev Med Chir Soc Med Nat Iasi 2015 Jan-Mar;119(1):135-40. PMID: 25970956
Clinicopathologic features of breast disease in Jamaica: findings of the Jamaican Breast Disease Study, 2000-2002.
Shirley SE, Mitchell DI, Soares DP, James M, Escoffery CT, Rhoden AM, Wolff C, Choy L, Wilks RJ
West Indian Med J 2008 Mar;57(2):90-4. PMID: 19565948
Histopathologic and flow-cytometric analysis of neoplastic and benign "background" tissue in breast carcinoma resections.
Visscher DW, Gingrich DS, Leon-Armin C, Tabaczka P, Crissman JD
Anal Cell Pathol 1998;17(3):167-75. doi: 10.1155/1998/294903. PMID: 10221331Free PMC Article
Benign proliferative disorders of the breast.
Ahn HJ, Cho NH, Yang WI, Choi IJ
Yonsei Med J 1990 Jun;31(2):168-73. doi: 10.3349/ymj.1990.31.2.168. PMID: 2219974

Therapy

COMPARISONS BETWEEN THE NON-PROLIFERATIVE AND PROLIFERATIVE THERAPY IN FIBROCYSTIC MASTOSIS.
Carauleanu A, Socolov R, Rugina V, Gabia O, Carauleanu DM, Lupascu IA, Socolov D
Rev Med Chir Soc Med Nat Iasi 2016 Apr-Jun;120(2):321-7. PMID: 27483712
Benign breast diseases, contraception and hormone replacement therapy.
Gadducci A, Guerrieri ME, Genazzani AR
Minerva Ginecol 2012 Feb;64(1):67-74. PMID: 22334232
A multi-center prospective cohort study of benign breast disease and risk of subsequent breast cancer.
Kabat GC, Jones JG, Olson N, Negassa A, Duggan C, Ginsberg M, Kandel RA, Glass AG, Rohan TE
Cancer Causes Control 2010 Jun;21(6):821-8. Epub 2010 Jan 19 doi: 10.1007/s10552-010-9508-7. PMID: 20084540Free PMC Article

Prognosis

Differences in breast cancer risk after benign breast disease by type of screening diagnosis.
Louro J, Román M, Posso M, Comerma L, Vidal C, Saladié F, Alcantara R, Sanchez M, Quintana MJ, Del Riego J, Ferrer J, Peñalva L, Bargalló X, Prieto M, Sala M, Castells X
Breast 2020 Dec;54:343-348. Epub 2020 Oct 3 doi: 10.1016/j.breast.2020.09.005. PMID: 33023825Free PMC Article
COMPARISONS BETWEEN THE NON-PROLIFERATIVE AND PROLIFERATIVE THERAPY IN FIBROCYSTIC MASTOSIS.
Carauleanu A, Socolov R, Rugina V, Gabia O, Carauleanu DM, Lupascu IA, Socolov D
Rev Med Chir Soc Med Nat Iasi 2016 Apr-Jun;120(2):321-7. PMID: 27483712
Benign breast disease and the risk of breast cancer in the next 15 years.
Socolov D, Anghelache I, Ilea C, Socolov R, Carauleanu A
Rev Med Chir Soc Med Nat Iasi 2015 Jan-Mar;119(1):135-40. PMID: 25970956

Clinical prediction guides

P53 Expression in benign Breast Disease Development: A Systematic Review.
Costa RSS, Silva IFD
Asian Pac J Cancer Prev 2020 Sep 1;21(9):2485-2491. doi: 10.31557/APJCP.2020.21.9.2485. PMID: 32986343Free PMC Article
Plasma equol concentration is not associated with breast cancer and fibrocystic breast conditions among women in Shanghai, China.
Atkinson C, Ray RM, Li W, Lin MG, Gao DL, Shannon J, Stalsberg H, Porter PL, Frankenfeld CL, Wähälä K, Thomas DB, Lampe JW
Nutr Res 2016 Aug;36(8):863-71. Epub 2016 Mar 30 doi: 10.1016/j.nutres.2016.03.008. PMID: 27440541Free PMC Article
Benign breast diseases, contraception and hormone replacement therapy.
Gadducci A, Guerrieri ME, Genazzani AR
Minerva Ginecol 2012 Feb;64(1):67-74. PMID: 22334232
Dietary and other risk factors in women having fibrocystic breast conditions with and without concurrent breast cancer: a nested case-control study in Shanghai, China.
Li W, Ray RM, Lampe JW, Lin MG, Gao DL, Wu C, Nelson ZC, Fitzgibbons ED, Horner N, Hu YW, Shannon J, Satia JA, Patterson RE, Stalsberg H, Thomas DB
Int J Cancer 2005 Jul 20;115(6):981-93. doi: 10.1002/ijc.20964. PMID: 15723298

Recent systematic reviews

P53 Expression in benign Breast Disease Development: A Systematic Review.
Costa RSS, Silva IFD
Asian Pac J Cancer Prev 2020 Sep 1;21(9):2485-2491. doi: 10.31557/APJCP.2020.21.9.2485. PMID: 32986343Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...