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Skin lymphangioma

MedGen UID:
232399
•Concept ID:
C1333176
•
Neoplastic Process
Synonyms: Cutaneous Lymphangioma; cutaneous lymphangioma; Lymphangioma of skin; Skin Lymphangioma; skin lymphangioma
SNOMED CT: Lymphangioma of skin (445492005)
 
Monarch Initiative: MONDO:0024673

Definition

A lymphangioma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin lymphangioma

Professional guidelines

PubMed

Japanese Clinical Practice Guidelines for Vascular Anomalies 2017.
Mimura H, Akita S, Fujino A, Jinnin M, Ozaki M, Osuga K, Nakaoka H, Morii E, Kuramochi A, Aoki Y, Arai Y, Aramaki N, Inoue M, Iwashina Y, Iwanaka T, Ueno S, Umezawa A, Ozeki M, Ochi J, Kinoshita Y, Kurita M, Seike S, Takakura N, Takahashi M, Tachibana T, Chuman K, Nagata S, Narushima M, Niimi Y, Nosaka S, Nozaki T, Hashimoto K, Hayashi A, Hirakawa S, Fujikawa A, Hori Y, Matsuoka K, Mori H, Yamamoto Y, Yuzuriha S, Rikihisa N, Watanabe S, Watanabe S, Kuroda T, Sugawara S, Ishikawa K, Sasaki S
J Dermatol 2020 May;47(5):e138-e183. Epub 2020 Mar 22 doi: 10.1111/1346-8138.15189. PMID: 32200557Free PMC Article
Classification of vascular disorders in the skin and selected data on new evaluation and treatment.
Wollina U, Unger L, Haroske G, Heinig B
Dermatol Ther 2012 Jul-Aug;25(4):287-96. doi: 10.1111/j.1529-8019.2012.01514.x. PMID: 22950555
Hemangiomas: evaluation and treatment.
Dinehart SM, Kincannon J, Geronemus R
Dermatol Surg 2001 May;27(5):475-85. doi: 10.1046/j.1524-4725.2001.00227.x. PMID: 11359498

Recent clinical studies

Etiology

Curettage and sclerotherapy technique: A hybrid approach to superficial lymphatic malformation.
Wang H, Zhou J, Lin W, Xie C, Yang W, Guo Z
Pediatr Dermatol 2023 Mar;40(2):265-269. Epub 2022 Nov 29 doi: 10.1111/pde.15202. PMID: 36444750
Verrucous lymphangioma circumscriptum.
Terushkin V, Marmon S, Fischer M, Patel RR, Sanchez MR
Dermatol Online J 2012 Dec 15;18(12):9. PMID: 23286799
Scrotal lymphangioma.
Yasui T, Akita H, Kobayashi K, Kohri K
Urol Int 1998;61(3):178-80. doi: 10.1159/000030318. PMID: 9933841
Targetoid hemosiderotic hemangioma.
Santa Cruz DJ, Aronberg J
J Am Acad Dermatol 1988 Sep;19(3):550-8. doi: 10.1016/s0190-9622(88)70211-x. PMID: 3170814
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Diagnosis

Verrucous Lymphangioma Circumscriptum.
Goyal M, Alam A
J Cutan Med Surg 2023 Nov;27(6):675. Epub 2023 Sep 19 doi: 10.1177/12034754231199751. PMID: 37724911
Cutaneous lymphangioma circumscriptum.
Kiran A, Komandla A
Pan Afr Med J 2023;45:46. Epub 2023 May 18 doi: 10.11604/pamj.2023.45.46.39047. PMID: 37575519Free PMC Article
Lymphoscintigraphic Findings of Scrotal Lymphangioma.
Shen G, Kuang A
Clin Nucl Med 2022 Oct 1;47(10):888-889. Epub 2022 Apr 27 doi: 10.1097/RLU.0000000000004209. PMID: 35383611
Vascular anomalies.
Mulliken JB, Fishman SJ, Burrows PE
Curr Probl Surg 2000 Aug;37(8):517-84. doi: 10.1016/s0011-3840(00)80013-1. PMID: 10955029
Benign lymphangioendothelioma.
Jones EW, Winkelmann RK, Zachary CB, Reda AM
J Am Acad Dermatol 1990 Aug;23(2 Pt 1):229-35. doi: 10.1016/0190-9622(90)70203-t. PMID: 2212118

Therapy

Dermatologic Sequelae Associated with Radiation Therapy.
Ashack KA, Kuritza V, Visconti MJ, Ashack L
Am J Clin Dermatol 2020 Aug;21(4):541-555. doi: 10.1007/s40257-020-00519-x. PMID: 32410134
Carbon dioxide laser for the treatment of microcystic lymphatic malformations (lymphangioma circumscriptum): a systematic review.
Savas JA, Ledon J, Franca K, Chacon A, Zaiac M, Nouri K
Dermatol Surg 2013 Aug;39(8):1147-57. Epub 2013 Apr 22 doi: 10.1111/dsu.12220. PMID: 23607875
Lasers for cutaneous congenital vascular lesions: a comprehensive overview and update.
França K, Chacon A, Ledon J, Savas J, Izakovic J, Nouri K
Lasers Med Sci 2013 Jul;28(4):1197-204. Epub 2012 Oct 24 doi: 10.1007/s10103-012-1220-2. PMID: 23093134
Multifocal lymphangioendotheliomatosis with thrombocytopenia.
Yeung J, Somers G, Viero S, Pope E
J Am Acad Dermatol 2006 May;54(5 Suppl):S214-7. doi: 10.1016/j.jaad.2005.07.029. PMID: 16631943
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997

Prognosis

Lymphangioma-like Kaposi sarcoma.
Ramirez JA, Laskin WB, Guitart J
J Cutan Pathol 2005 Apr;32(4):286-92. doi: 10.1111/j.0303-6987.2005.00323.x. PMID: 15769278
Thoracic lymphangiomatosis in a child.
Alvarez OA, Kjellin I, Zuppan CW
J Pediatr Hematol Oncol 2004 Feb;26(2):136-41. doi: 10.1097/00043426-200402000-00018. PMID: 14767208
Scrotal lymphangioma.
Yasui T, Akita H, Kobayashi K, Kohri K
Urol Int 1998;61(3):178-80. doi: 10.1159/000030318. PMID: 9933841
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Clinical prediction guides

Curettage and sclerotherapy technique: A hybrid approach to superficial lymphatic malformation.
Wang H, Zhou J, Lin W, Xie C, Yang W, Guo Z
Pediatr Dermatol 2023 Mar;40(2):265-269. Epub 2022 Nov 29 doi: 10.1111/pde.15202. PMID: 36444750
Acquired lymphangiectasia: a rare mimic of genital warts.
Simeonovski V, Kostovski M, Gjoric I, Damevska S, Igor P
Dermatol Online J 2020 Dec 15;26(12) PMID: 33423429
Acquired lymphangiomas mimicking multiple hallux warts.
Diani M, Turina M, Cozzi C, Altomare G
An Bras Dermatol 2017;92(5 Suppl 1):11-13. doi: 10.1590/abd1806-4841.20175685. PMID: 29267433Free PMC Article
Congenital and infantile skin lesions affecting the hand and upper extremity, part 1: vascular neoplasms and malformations.
Willard KJ, Cappel MA, Kozin SH, Abzug JM
J Hand Surg Am 2013 Nov;38(11):2271-83. Epub 2013 May 23 doi: 10.1016/j.jhsa.2013.03.040. PMID: 23707594
Lymphangioma circumscriptum of the vulva: a review of the literature.
Vlastos AT, Malpica A, Follen M
Obstet Gynecol 2003 May;101(5 Pt 1):946-54. doi: 10.1016/s0029-7844(03)00048-6. PMID: 12738156

Recent systematic reviews

Carbon dioxide laser for the treatment of microcystic lymphatic malformations (lymphangioma circumscriptum): a systematic review.
Savas JA, Ledon J, Franca K, Chacon A, Zaiac M, Nouri K
Dermatol Surg 2013 Aug;39(8):1147-57. Epub 2013 Apr 22 doi: 10.1111/dsu.12220. PMID: 23607875

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