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Skin lymphangioma

MedGen UID:
232399
•Concept ID:
C1333176
•
Neoplastic Process
Synonyms: Cutaneous Lymphangioma; cutaneous lymphangioma; Lymphangioma of skin; Skin Lymphangioma; skin lymphangioma
SNOMED CT: Lymphangioma of skin (445492005)
 
Monarch Initiative: MONDO:0024673

Definition

A lymphangioma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin lymphangioma

Professional guidelines

PubMed

Japanese Clinical Practice Guidelines for Vascular Anomalies 2017.
Mimura H, Akita S, Fujino A, Jinnin M, Ozaki M, Osuga K, Nakaoka H, Morii E, Kuramochi A, Aoki Y, Arai Y, Aramaki N, Inoue M, Iwashina Y, Iwanaka T, Ueno S, Umezawa A, Ozeki M, Ochi J, Kinoshita Y, Kurita M, Seike S, Takakura N, Takahashi M, Tachibana T, Chuman K, Nagata S, Narushima M, Niimi Y, Nosaka S, Nozaki T, Hashimoto K, Hayashi A, Hirakawa S, Fujikawa A, Hori Y, Matsuoka K, Mori H, Yamamoto Y, Yuzuriha S, Rikihisa N, Watanabe S, Watanabe S, Kuroda T, Sugawara S, Ishikawa K, Sasaki S
J Dermatol 2020 May;47(5):e138-e183. Epub 2020 Mar 22 doi: 10.1111/1346-8138.15189. PMID: 32200557Free PMC Article
Hemangiomas: evaluation and treatment.
Dinehart SM, Kincannon J, Geronemus R
Dermatol Surg 2001 May;27(5):475-85. doi: 10.1046/j.1524-4725.2001.00227.x. PMID: 11359498
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997

Recent clinical studies

Etiology

Verrucous lymphangioma circumscriptum.
Terushkin V, Marmon S, Fischer M, Patel RR, Sanchez MR
Dermatol Online J 2012 Dec 15;18(12):9. PMID: 23286799
Cutaneous lymphangioma circumscriptum: frog spawn on the skin.
Patel GA, Schwartz RA
Int J Dermatol 2009 Dec;48(12):1290-5. doi: 10.1111/j.1365-4632.2009.04226.x. PMID: 19930489
Scrotal lymphangioma.
Yasui T, Akita H, Kobayashi K, Kohri K
Urol Int 1998;61(3):178-80. doi: 10.1159/000030318. PMID: 9933841
Targetoid hemosiderotic hemangioma.
Santa Cruz DJ, Aronberg J
J Am Acad Dermatol 1988 Sep;19(3):550-8. doi: 10.1016/s0190-9622(88)70211-x. PMID: 3170814
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Diagnosis

Verrucous Lymphangioma Circumscriptum.
Goyal M, Alam A
J Cutan Med Surg 2023 Nov;27(6):675. Epub 2023 Sep 19 doi: 10.1177/12034754231199751. PMID: 37724911
Cutaneous lymphangioma circumscriptum.
Kiran A, Komandla A
Pan Afr Med J 2023;45:46. Epub 2023 May 18 doi: 10.11604/pamj.2023.45.46.39047. PMID: 37575519Free PMC Article
Lymphoscintigraphic Findings of Scrotal Lymphangioma.
Shen G, Kuang A
Clin Nucl Med 2022 Oct 1;47(10):888-889. Epub 2022 Apr 27 doi: 10.1097/RLU.0000000000004209. PMID: 35383611
US of Pediatric Superficial Masses of the Head and Neck.
Bansal AG, Oudsema R, Masseaux JA, Rosenberg HK
Radiographics 2018 Jul-Aug;38(4):1239-1263. doi: 10.1148/rg.2018170165. PMID: 29995618
Lymphangioma circumscriptum.
Heller M, Mengden S
Dermatol Online J 2008 May 15;14(5):27. PMID: 18627763

Therapy

Computed Tomography Image Characteristics before and after Interventional Treatment of Children's Lymphangioma under Artificial Intelligence Algorithm.
Yin C, Wang S, Pan D
Comput Math Methods Med 2021;2021:2673013. Epub 2021 Dec 9 doi: 10.1155/2021/2673013. PMID: 34925537Free PMC Article
Dermatologic Sequelae Associated with Radiation Therapy.
Ashack KA, Kuritza V, Visconti MJ, Ashack L
Am J Clin Dermatol 2020 Aug;21(4):541-555. doi: 10.1007/s40257-020-00519-x. PMID: 32410134
Highly selective electrocoagulation therapy: an innovative treatment for lymphangioma circumscriptum.
Yang X, Jin Y, Chen H, Li S, Ma G, Hu X, Qiu Y, Yu W, Chang L, Wang T, Lin X
Dermatol Surg 2014 Aug;40(8):899-905. doi: 10.1111/dsu.0000000000000061. PMID: 24978646
Lasers for cutaneous congenital vascular lesions: a comprehensive overview and update.
França K, Chacon A, Ledon J, Savas J, Izakovic J, Nouri K
Lasers Med Sci 2013 Jul;28(4):1197-204. Epub 2012 Oct 24 doi: 10.1007/s10103-012-1220-2. PMID: 23093134
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997

Prognosis

Lymphangioma-like Kaposi sarcoma.
Ramirez JA, Laskin WB, Guitart J
J Cutan Pathol 2005 Apr;32(4):286-92. doi: 10.1111/j.0303-6987.2005.00323.x. PMID: 15769278
Scrotal lymphangioma.
Yasui T, Akita H, Kobayashi K, Kohri K
Urol Int 1998;61(3):178-80. doi: 10.1159/000030318. PMID: 9933841
Congenital malformations of the cervicothoracic lymphatic system: embryology and pathogenesis.
Zadvinskis DP, Benson MT, Kerr HH, Mancuso AA, Cacciarelli AA, Madrazo BL, Mafee MF, Dalen K
Radiographics 1992 Nov;12(6):1175-89. doi: 10.1148/radiographics.12.6.1439020. PMID: 1439020
Vascular and lymphatic tumors in infancy, childhood and adulthood: challenge of diagnosis and treatment.
Edgerton MT, Hiebert JM
Curr Probl Cancer 1978 Jan;2(7):1-44. doi: 10.1016/s0147-0272(78)80001-4. PMID: 373997
Cutaneous lymphangioma.
Flanagan BP, Helwig EB
Arch Dermatol 1977 Jan;113(1):24-30. PMID: 831620

Clinical prediction guides

Curettage and sclerotherapy technique: A hybrid approach to superficial lymphatic malformation.
Wang H, Zhou J, Lin W, Xie C, Yang W, Guo Z
Pediatr Dermatol 2023 Mar;40(2):265-269. Epub 2022 Nov 29 doi: 10.1111/pde.15202. PMID: 36444750
Congenital and infantile skin lesions affecting the hand and upper extremity, part 1: vascular neoplasms and malformations.
Willard KJ, Cappel MA, Kozin SH, Abzug JM
J Hand Surg Am 2013 Nov;38(11):2271-83. Epub 2013 May 23 doi: 10.1016/j.jhsa.2013.03.040. PMID: 23707594
Lymphangioma circumscriptum of the vulva: a review of the literature.
Vlastos AT, Malpica A, Follen M
Obstet Gynecol 2003 May;101(5 Pt 1):946-54. doi: 10.1016/s0029-7844(03)00048-6. PMID: 12738156
CD31 immunoreactivity in mesenchymal neoplasms of the skin and subcutis: report of 145 cases and review of putative immunohistologic markers of endothelial differentiation.
DeYoung BR, Swanson PE, Argenyi ZB, Ritter JH, Fitzgibbon JF, Stahl DJ, Hoover W, Wick MR
J Cutan Pathol 1995 Jun;22(3):215-22. doi: 10.1111/j.1600-0560.1995.tb00741.x. PMID: 7593814
Congenital malformations of the cervicothoracic lymphatic system: embryology and pathogenesis.
Zadvinskis DP, Benson MT, Kerr HH, Mancuso AA, Cacciarelli AA, Madrazo BL, Mafee MF, Dalen K
Radiographics 1992 Nov;12(6):1175-89. doi: 10.1148/radiographics.12.6.1439020. PMID: 1439020

Recent systematic reviews

Carbon dioxide laser for the treatment of microcystic lymphatic malformations (lymphangioma circumscriptum): a systematic review.
Savas JA, Ledon J, Franca K, Chacon A, Zaiac M, Nouri K
Dermatol Surg 2013 Aug;39(8):1147-57. Epub 2013 Apr 22 doi: 10.1111/dsu.12220. PMID: 23607875

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