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Malignant mixed epithelial stromal tumor of the kidney

MedGen UID:
233156
•Concept ID:
C1334602
•
Neoplastic Process
Synonyms: Kidney Malignant Mixed Epithelial and Stromal Tumor; Malignant Kidney Mixed Epithelial and Stromal Tumor; Malignant MEST; malignant MEST; Malignant Mixed Epithelial and Stromal Tumor of the Kidney; Malignant Mixed Epithelial Stromal Tumor of the Kidney; malignant mixed epithelial stromal tumor of the kidney; mixed epithelial stromal tumor of the kidney, malignant; mixed epithelial stromal tumour of the kidney, malignant
 
Monarch Initiative: MONDO:0024711

Definition

A mixed epithelial stromal tumor of the kidney with malignant stromal features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant mixed epithelial stromal tumor of the kidney

Professional guidelines

PubMed

Immunohistochemical characteristics of renomedullary interstitial cell tumor: a study of 41 tumors with emphasis on differential diagnosis of mesenchymal neoplasms.
Lu Z, Al-Obaidy K, Cheng L, Perry KD, Grignon DJ, Williamson SR
Hum Pathol 2018 Dec;82:46-50. Epub 2018 Jul 18 doi: 10.1016/j.humpath.2018.07.010. PMID: 30031100
Tubulocystic renal cell carcinoma: a review of literature focused on radiological findings for differential diagnosis.
Honda Y, Nakamura Y, Goto K, Terada H, Sentani K, Yasui W, Sekino Y, Hayashi T, Teishima J, Matsubara A, Akagi M, Fuji T, Baba Y, Iida M, Awai K
Abdom Radiol (NY) 2018 Jul;43(7):1540-1545. doi: 10.1007/s00261-018-1643-8. PMID: 29796844
Uterine adenosarcoma: a clinicopathologic study of 11 cases with a reevaluation of histologic criteria.
Czernobilsky B, Hohlweg-Majert P, Dallenbach-Hellweg G
Arch Gynecol 1983;233(4):281-94. doi: 10.1007/BF02133803. PMID: 6318673

Recent clinical studies

Therapy

The effect of preoperative chemotherapy on histological subtyping and staging of Wilms tumors: The United Kingdom Children's Cancer Study Group (UKCCSG) Wilms tumor trial 3 (UKW3) experience.
Vujanić GM, D'Hooghe E, Popov SD, Sebire NJ, Kelsey A
Pediatr Blood Cancer 2019 Mar;66(3):e27549. Epub 2018 Nov 8 doi: 10.1002/pbc.27549. PMID: 30408319
Increased risk of solid renal tumors in lithium-treated patients.
Zaidan M, Stucker F, Stengel B, Vasiliu V, Hummel A, Landais P, Boffa JJ, Ronco P, Grünfeld JP, Servais A
Kidney Int 2014 Jul;86(1):184-90. Epub 2014 Jan 22 doi: 10.1038/ki.2014.2. PMID: 24451323
Mixed epithelial and stromal tumors of the kidney: evidence for a single cell of origin with capacity for epithelial and stromal differentiation.
Kum JB, Grignon DJ, Wang M, Zhou M, Montironi R, Shen SS, Zhang S, Lopez-Beltran A, Eble JN, Cheng L
Am J Surg Pathol 2011 Aug;35(8):1114-22. doi: 10.1097/PAS.0b013e3182233fb6. PMID: 21753695
Aggressive mixed epithelial-stromal tumour of the kidney treated with chemotherapy and radiotherapy.
Yap YS, Coleman M, Olver I
Lancet Oncol 2004 Dec;5(12):747-9. doi: 10.1016/S1470-2045(04)01651-1. PMID: 15581546
Mixed epithelial and stromal tumor of the kidney.
Adsay NV, Eble JN, Srigley JR, Jones EC, Grignon DJ
Am J Surg Pathol 2000 Jul;24(7):958-70. doi: 10.1097/00000478-200007000-00007. PMID: 10895818

Prognosis

Mixed epithelial and stromal tumor of the kidney: report of eight cases and literature review.
Wang CJ, Lin YW, Xiang H, Fang DB, Jiang P, Shen BH
World J Surg Oncol 2013 Aug 20;11(1):207. doi: 10.1186/1477-7819-11-207. PMID: 23958048Free PMC Article
Mixed epithelial and stromal tumor of the kidney.
Zheng S, Yuan HC, Liu LR, Wei Q, Han P
Kaohsiung J Med Sci 2013 May;29(5):280-3. Epub 2012 Dec 21 doi: 10.1016/j.kjms.2012.09.008. PMID: 23639516
Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study.
Alexiev BA, Drachenberg CB
Virchows Arch 2013 May;462(5):575-81. Epub 2013 Mar 24 doi: 10.1007/s00428-013-1398-0. PMID: 23525677
Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update.
Moslemi MK
Urol J 2010 Summer;7(3):141-7. PMID: 20845287
2009 update on the classification of renal epithelial tumors in adults.
Lopez-Beltran A, Carrasco JC, Cheng L, Scarpelli M, Kirkali Z, Montironi R
Int J Urol 2009 May;16(5):432-43. Epub 2009 Apr 20 doi: 10.1111/j.1442-2042.2009.02302.x. PMID: 19453547

Clinical prediction guides

Mixed epithelial and stromal tumor of the kidney: A retrospective clinicopathological evaluation.
Feng R, Zhang T, Ke C, Tao Y, Wang Y
Ann Diagn Pathol 2023 Apr;63:152088. Epub 2022 Dec 23 doi: 10.1016/j.anndiagpath.2022.152088. PMID: 36577187
Mixed Epithelial and Stromal Tumor Family of Kidney (Adult Cystic Nephroma, Mixed Epithelial and Stromal Tumor): Retrospective Clinicopathological Evaluation.
Demir H, Sahin Z, Ozman O, Demirbilek M, Ozden SB, Gurses I, Durak H, Uygun N, Onal B
Turk Patoloji Derg 2022;38(3):251-260. doi: 10.5146/tjpath.2022.01575. PMID: 35642344Free PMC Article
Differentiating the clinical and computed tomography imaging features of mixed epithelial and stromal tumors of the kidney to establish a treatment plan.
Chen J, Liu H, Li M, Liu W, Masokano IB, Pei Y, Li W
J Appl Clin Med Phys 2022 Jan;23(1):e13486. Epub 2021 Dec 3 doi: 10.1002/acm2.13486. PMID: 34861098Free PMC Article
Clinical-radiologic correlation of mixed epithelial and stromal tumor of the kidneys: Cases analysis.
Tsai SH, Wang JH, Lai YC, Chang YH, Chung HJ, Chang LS
J Chin Med Assoc 2016 Oct;79(10):554-8. Epub 2016 Jun 24 doi: 10.1016/j.jcma.2016.02.012. PMID: 27349941
Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update.
Moslemi MK
Urol J 2010 Summer;7(3):141-7. PMID: 20845287

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