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Malignant Superior Vena Cava Neoplasm

MedGen UID:
233161
•Concept ID:
C1334623
•
Neoplastic Process
Synonyms: Malignant Neoplasm of Superior Vena Cava; Malignant Neoplasm of the Superior Vena Cava; Malignant Tumor of Superior Vena Cava; Malignant Tumor of the Superior Vena Cava

Definition

A malignant neoplasm involving the superior vena cava. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Superior Vena Cava Neoplasm

Professional guidelines

PubMed

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Oncologic Emergencies: Recognition and Initial Management.
Higdon ML, Atkinson CJ, Lawrence KV
Am Fam Physician 2018 Jun 1;97(11):741-748. PMID: 30215936
Treatment of venous stenosis in oncologic patients.
Ierardi AM, Jannone ML, Petrillo M, Brambillasca PM, Fumarola EM, Angileri SA, Crippa M, Carrafiello G
Future Oncol 2018 Dec;14(28):2933-2943. Epub 2018 Apr 6 doi: 10.2217/fon-2017-0737. PMID: 29623736

Recent clinical studies

Etiology

Clinical analysis of 48 cases of malignant superior vena cava syndrome.
Sun M, Chen X, Li H, Zhang X, Wang X, Zheng R, Li G, Wang L, Li D
World J Surg Oncol 2021 Jun 23;19(1):185. doi: 10.1186/s12957-021-02300-8. PMID: 34162380Free PMC Article
Superior vena cava replacement for epithelioid haemangioendothelioma.
Svitek V, Dzian A, Mičák J
Interact Cardiovasc Thorac Surg 2021 Oct 4;33(4):668-670. doi: 10.1093/icvts/ivab136. PMID: 33948629Free PMC Article
Thrombosis, anticoagulation and outcomes in malignant superior vena cava syndrome.
Ratzon R, Tamir S, Friehmann T, Livneh N, Dudnik E, Rozental A, Hamburger-Avnery O, Pereg D, Derazne E, Brenner B, Raanani P, Ten Cate H, Spectre G, Leader A
J Thromb Thrombolysis 2019 Jan;47(1):121-128. doi: 10.1007/s11239-018-1747-6. PMID: 30255420
Pediatric superior vena cava syndrome: An evidence-based systematic review of the literature.
Nossair F, Schoettler P, Starr J, Chan AKC, Kirov I, Paes B, Mahajerin A
Pediatr Blood Cancer 2018 Sep;65(9):e27225. Epub 2018 May 21 doi: 10.1002/pbc.27225. PMID: 29781569
An atlas to aid delineation of para-aortic lymph node region in cervical cancer: Design and validation of contouring guidelines.
Keenan LG, Rock K, Azmi A, Salib O, Gillham C, McArdle O
Radiother Oncol 2018 Jun;127(3):417-422. Epub 2018 Mar 6 doi: 10.1016/j.radonc.2018.02.013. PMID: 29523410

Diagnosis

Oncologic Emergencies: Traditional and Contemporary.
Spring J, Munshi L
Crit Care Clin 2021 Jan;37(1):85-103. Epub 2020 Oct 29 doi: 10.1016/j.ccc.2020.08.004. PMID: 33190777
Oncologic Mechanical Emergencies.
Khan UA, Shanholtz CB, McCurdy MT
Hematol Oncol Clin North Am 2017 Dec;31(6):927-940. doi: 10.1016/j.hoc.2017.08.001. PMID: 29078930
Oncologic mechanical emergencies.
Khan UA, Shanholtz CB, McCurdy MT
Emerg Med Clin North Am 2014 Aug;32(3):495-508. Epub 2014 Jun 7 doi: 10.1016/j.emc.2014.04.001. PMID: 25060246
Oncologic emergencies.
McCurdy MT, Shanholtz CB
Crit Care Med 2012 Jul;40(7):2212-22. doi: 10.1097/CCM.0b013e31824e1865. PMID: 22584756
Clinical practice. Superior vena cava syndrome with malignant causes.
Wilson LD, Detterbeck FC, Yahalom J
N Engl J Med 2007 May 3;356(18):1862-9. doi: 10.1056/NEJMcp067190. PMID: 17476012

Therapy

Malignant Superior Vena Cava Syndrome: A Scoping Review.
Wright K, Digby GC, Gyawali B, Jad R, Menard A, Moraes FY, Wijeratne DT
J Thorac Oncol 2023 Oct;18(10):1268-1276. Epub 2023 May 3 doi: 10.1016/j.jtho.2023.04.019. PMID: 37146753
Cardiovascular Oncologic Emergencies.
Shenoy S, Shetty S, Lankala S, Anwer F, Yeager A, Adigopula S
Cardiology 2017;138(3):147-158. Epub 2017 Jun 28 doi: 10.1159/000475491. PMID: 28654925
Oncologic emergencies.
McCurdy MT, Shanholtz CB
Crit Care Med 2012 Jul;40(7):2212-22. doi: 10.1097/CCM.0b013e31824e1865. PMID: 22584756
Superior vena cava syndrome.
Wan JF, Bezjak A
Emerg Med Clin North Am 2009 May;27(2):243-55. doi: 10.1016/j.emc.2009.01.003. PMID: 19447309
Superior vena cava syndrome.
Wudel LJ Jr, Nesbitt JC
Curr Treat Options Oncol 2001 Feb;2(1):77-91. doi: 10.1007/s11864-001-0019-3. PMID: 12057143

Prognosis

Malignant superior vena cava obstruction.
Yingchoncharoen P, Sanchez S, Alsuwayah M, Abdelnabi M
BMJ Case Rep 2024 May 8;17(5) doi: 10.1136/bcr-2024-260690. PMID: 38719256Free PMC Article
Clinical analysis of 48 cases of malignant superior vena cava syndrome.
Sun M, Chen X, Li H, Zhang X, Wang X, Zheng R, Li G, Wang L, Li D
World J Surg Oncol 2021 Jun 23;19(1):185. doi: 10.1186/s12957-021-02300-8. PMID: 34162380Free PMC Article
Pediatric superior vena cava syndrome: An evidence-based systematic review of the literature.
Nossair F, Schoettler P, Starr J, Chan AKC, Kirov I, Paes B, Mahajerin A
Pediatr Blood Cancer 2018 Sep;65(9):e27225. Epub 2018 May 21 doi: 10.1002/pbc.27225. PMID: 29781569
Oncological emergencies: superior vena cava syndrome.
Bochenek-Cibor J, Püsküllüoğlu M, Zygulska A
Przegl Lek 2014;71(12):697-9. PMID: 25951699
Oncologic emergencies.
McCurdy MT, Shanholtz CB
Crit Care Med 2012 Jul;40(7):2212-22. doi: 10.1097/CCM.0b013e31824e1865. PMID: 22584756

Clinical prediction guides

Clinical analysis of 48 cases of malignant superior vena cava syndrome.
Sun M, Chen X, Li H, Zhang X, Wang X, Zheng R, Li G, Wang L, Li D
World J Surg Oncol 2021 Jun 23;19(1):185. doi: 10.1186/s12957-021-02300-8. PMID: 34162380Free PMC Article
Outcomes and Safety Analysis in Superior Vena Cava Resection for Extended Thymic Epithelial Tumors.
Bertolaccini L, Prisciandaro E, Galetta D, Casiraghi M, Guarize J, Petrella F, Sedda G, Lo Iacono G, Brambilla D, Spaggiari L
Ann Thorac Surg 2021 Jul;112(1):271-277. Epub 2020 Oct 14 doi: 10.1016/j.athoracsur.2020.07.069. PMID: 33068543
Pediatric superior vena cava syndrome: An evidence-based systematic review of the literature.
Nossair F, Schoettler P, Starr J, Chan AKC, Kirov I, Paes B, Mahajerin A
Pediatr Blood Cancer 2018 Sep;65(9):e27225. Epub 2018 May 21 doi: 10.1002/pbc.27225. PMID: 29781569
Cardiac tamponade.
Knoop T, Willenberg K
Semin Oncol Nurs 1999 Aug;15(3):168-73. doi: 10.1016/s0749-2081(99)80004-7. PMID: 10461701
Oncologic emergencies.
Kelly KM, Lange B
Pediatr Clin North Am 1997 Aug;44(4):809-30. doi: 10.1016/s0031-3955(05)70531-9. PMID: 9286286

Recent systematic reviews

Venous thromboembolism in orthopaedic oncology.
Lex JR, Evans S, Cool P, Gregory J, Ashford RU, Rankin KS, Cosker T, Kumar A, Gerrand C, Stevenson J; British Orthopaedic Oncology Society VTE Committee
Bone Joint J 2020 Dec;102-B(12):1743-1751. doi: 10.1302/0301-620X.102B12.BJJ-2019-1136.R3. PMID: 33249908
Pediatric superior vena cava syndrome: An evidence-based systematic review of the literature.
Nossair F, Schoettler P, Starr J, Chan AKC, Kirov I, Paes B, Mahajerin A
Pediatr Blood Cancer 2018 Sep;65(9):e27225. Epub 2018 May 21 doi: 10.1002/pbc.27225. PMID: 29781569
WITHDRAWN: Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus.
Rowell NP, Gleeson FV
Cochrane Database Syst Rev 2015 Mar 10;2015(3):CD001316. doi: 10.1002/14651858.CD001316.pub2. PMID: 25756659Free PMC Article
Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus: a systematic review.
Rowell NP, Gleeson FV
Clin Oncol (R Coll Radiol) 2002 Oct;14(5):338-51. doi: 10.1053/clon.2002.0095. PMID: 12555872
Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus.
Rowell NP, Gleeson FV
Cochrane Database Syst Rev 2001;(4):CD001316. doi: 10.1002/14651858.CD001316. PMID: 11687105

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