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Anaplastic Lymphoma Post-Transplant Lymphoproliferative Disorder

MedGen UID:
233984
•Concept ID:
C1332284
•
Neoplastic Process
Synonyms: Anaplastic Diffuse Large B-Cell Lymphoma PTLD; Anaplastic Lymphoma PTLD

Definition

An anaplastic lymphoma that arises in a patient with a history of organ transplantation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Lymphoma Post-Transplant Lymphoproliferative Disorder

Professional guidelines

PubMed

Brentuximab vedotin for treatment of non-Hodgkin lymphomas: A systematic review.
Berger GK, McBride A, Lawson S, Royball K, Yun S, Gee K, Bin Riaz I, Saleh AA, Puvvada S, Anwer F
Crit Rev Oncol Hematol 2017 Jan;109:42-50. Epub 2016 Nov 21 doi: 10.1016/j.critrevonc.2016.11.009. PMID: 28010897Free PMC Article

Recent clinical studies

Etiology

Hematopoietic Stem Cell Transplantation in T Cell and Natural Killer Cell Lymphomas: Update on Recent Advances.
Boo YL, Koh LP
Transplant Cell Ther 2021 Jul;27(7):571-588. Epub 2021 Apr 20 doi: 10.1016/j.jtct.2021.04.002. PMID: 33857661
Anaplastic large cell lymphoma in human immunodeficiency virus-infected people and solid organ transplant recipients.
Mahale P, Weisenburger DD, Kahn AR, Gonsalves L, Pawlish K, Koch L, Tirado-Gomez M, Clarke CA, Alverson G, Shiels MS, Engels EA
Br J Haematol 2021 Feb;192(3):514-521. Epub 2020 Jun 8 doi: 10.1111/bjh.16778. PMID: 32510592
Brentuximab vedotin for treatment of non-Hodgkin lymphomas: A systematic review.
Berger GK, McBride A, Lawson S, Royball K, Yun S, Gee K, Bin Riaz I, Saleh AA, Puvvada S, Anwer F
Crit Rev Oncol Hematol 2017 Jan;109:42-50. Epub 2016 Nov 21 doi: 10.1016/j.critrevonc.2016.11.009. PMID: 28010897Free PMC Article
Childhood, adolescent and young adult non-Hodgkin lymphoma: state of the science.
Cairo MS, Pinkerton R
Br J Haematol 2016 May;173(4):507-30. Epub 2016 May 2 doi: 10.1111/bjh.14035. PMID: 27133800
Controversies in autologous and allogeneic hematopoietic cell transplantation in peripheral T/NK-cell lymphomas.
Shustov A
Best Pract Res Clin Haematol 2013 Mar;26(1):89-99. Epub 2013 May 25 doi: 10.1016/j.beha.2013.04.008. PMID: 23768643

Diagnosis

Diagnostic, prognostic and therapeutic role of CD30 in lymphoma.
Pierce JM, Mehta A
Expert Rev Hematol 2017 Jan;10(1):29-37. Epub 2016 Dec 21 doi: 10.1080/17474086.2017.1270202. PMID: 27927047
Childhood, adolescent and young adult non-Hodgkin lymphoma: state of the science.
Cairo MS, Pinkerton R
Br J Haematol 2016 May;173(4):507-30. Epub 2016 May 2 doi: 10.1111/bjh.14035. PMID: 27133800
Controversies in autologous and allogeneic hematopoietic cell transplantation in peripheral T/NK-cell lymphomas.
Shustov A
Best Pract Res Clin Haematol 2013 Mar;26(1):89-99. Epub 2013 May 25 doi: 10.1016/j.beha.2013.04.008. PMID: 23768643
Cutaneous presentation of post-renal transplant lymphoproliferative disorder: a series of four cases.
Salama S, Todd S, Cina DP, Margetts P
J Cutan Pathol 2010 Jun;37(6):641-53. Epub 2009 Nov 9 doi: 10.1111/j.1600-0560.2009.01449.x. PMID: 19903218
Soluble CD30 serum level--an adequate marker for allograft rejection of solid organs?
Schlaf G, Altermann WW, Rothhoff A, Seliger B
Histol Histopathol 2007 Nov;22(11):1269-79. doi: 10.14670/HH-22.1269. PMID: 17647199

Therapy

Anaplastic large cell lymphoma in human immunodeficiency virus-infected people and solid organ transplant recipients.
Mahale P, Weisenburger DD, Kahn AR, Gonsalves L, Pawlish K, Koch L, Tirado-Gomez M, Clarke CA, Alverson G, Shiels MS, Engels EA
Br J Haematol 2021 Feb;192(3):514-521. Epub 2020 Jun 8 doi: 10.1111/bjh.16778. PMID: 32510592
Brentuximab vedotin for treatment of non-Hodgkin lymphomas: A systematic review.
Berger GK, McBride A, Lawson S, Royball K, Yun S, Gee K, Bin Riaz I, Saleh AA, Puvvada S, Anwer F
Crit Rev Oncol Hematol 2017 Jan;109:42-50. Epub 2016 Nov 21 doi: 10.1016/j.critrevonc.2016.11.009. PMID: 28010897Free PMC Article
Diagnostic, prognostic and therapeutic role of CD30 in lymphoma.
Pierce JM, Mehta A
Expert Rev Hematol 2017 Jan;10(1):29-37. Epub 2016 Dec 21 doi: 10.1080/17474086.2017.1270202. PMID: 27927047
Cutaneous lymphoproliferative disorders in organ transplant recipients: update 2014.
Seçkin D
G Ital Dermatol Venereol 2014 Aug;149(4):401-8. PMID: 25068227
Controversies in autologous and allogeneic hematopoietic cell transplantation in peripheral T/NK-cell lymphomas.
Shustov A
Best Pract Res Clin Haematol 2013 Mar;26(1):89-99. Epub 2013 May 25 doi: 10.1016/j.beha.2013.04.008. PMID: 23768643

Prognosis

Hematopoietic Stem Cell Transplantation in T Cell and Natural Killer Cell Lymphomas: Update on Recent Advances.
Boo YL, Koh LP
Transplant Cell Ther 2021 Jul;27(7):571-588. Epub 2021 Apr 20 doi: 10.1016/j.jtct.2021.04.002. PMID: 33857661
Anaplastic large cell lymphoma in human immunodeficiency virus-infected people and solid organ transplant recipients.
Mahale P, Weisenburger DD, Kahn AR, Gonsalves L, Pawlish K, Koch L, Tirado-Gomez M, Clarke CA, Alverson G, Shiels MS, Engels EA
Br J Haematol 2021 Feb;192(3):514-521. Epub 2020 Jun 8 doi: 10.1111/bjh.16778. PMID: 32510592
Diagnostic, prognostic and therapeutic role of CD30 in lymphoma.
Pierce JM, Mehta A
Expert Rev Hematol 2017 Jan;10(1):29-37. Epub 2016 Dec 21 doi: 10.1080/17474086.2017.1270202. PMID: 27927047
Cutaneous lymphoproliferative disorders in organ transplant recipients: update 2014.
Seçkin D
G Ital Dermatol Venereol 2014 Aug;149(4):401-8. PMID: 25068227
Controversies in autologous and allogeneic hematopoietic cell transplantation in peripheral T/NK-cell lymphomas.
Shustov A
Best Pract Res Clin Haematol 2013 Mar;26(1):89-99. Epub 2013 May 25 doi: 10.1016/j.beha.2013.04.008. PMID: 23768643

Clinical prediction guides

Three different histological subtypes of Epstein-Barr virus-negative post-transplant lymphoproliferative disorder in a patient with hepatitis C infection.
Kobayashi M, Asano N, Fukushima M, Honda T
Int J Hematol 2014 Sep;100(3):307-11. Epub 2014 May 31 doi: 10.1007/s12185-014-1599-6. PMID: 24879033
Controversies in autologous and allogeneic hematopoietic cell transplantation in peripheral T/NK-cell lymphomas.
Shustov A
Best Pract Res Clin Haematol 2013 Mar;26(1):89-99. Epub 2013 May 25 doi: 10.1016/j.beha.2013.04.008. PMID: 23768643
Risk of lymphoma subtypes after solid organ transplantation in the United States.
Clarke CA, Morton LM, Lynch C, Pfeiffer RM, Hall EC, Gibson TM, Weisenburger DD, Martínez-Maza O, Hussain SK, Yang J, Chang ET, Engels EA
Br J Cancer 2013 Jul 9;109(1):280-8. Epub 2013 Jun 11 doi: 10.1038/bjc.2013.294. PMID: 23756857Free PMC Article
Soluble CD30 serum level--an adequate marker for allograft rejection of solid organs?
Schlaf G, Altermann WW, Rothhoff A, Seliger B
Histol Histopathol 2007 Nov;22(11):1269-79. doi: 10.14670/HH-22.1269. PMID: 17647199
Lymphoma resembling Hodgkin disease after posttransplant lymphoproliferative disorder in a liver transplant recipient.
Nalesnik MA, Randhawa P, Demetris AJ, Casavilla A, Fung JJ, Locker J
Cancer 1993 Nov 1;72(9):2568-73. doi: 10.1002/1097-0142(19931101)72:9<2568::aid-cncr2820720910>3.0.co;2-d. PMID: 8402478

Recent systematic reviews

Brentuximab vedotin for treatment of non-Hodgkin lymphomas: A systematic review.
Berger GK, McBride A, Lawson S, Royball K, Yun S, Gee K, Bin Riaz I, Saleh AA, Puvvada S, Anwer F
Crit Rev Oncol Hematol 2017 Jan;109:42-50. Epub 2016 Nov 21 doi: 10.1016/j.critrevonc.2016.11.009. PMID: 28010897Free PMC Article

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