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Classical Burkitt Lymphoma

MedGen UID:
234153
Concept ID:
C1333063
Neoplastic Process
Synonym: Classical Burkitt's Lymphoma

Definition

A Burkitt lymphoma characterized by the presence of a uniform malignant lymphocytic infiltrate that is composed of medium-sized cells with round nuclei and multiple basophilic nucleoli, abundant mitotic figures, and a starry-sky pattern due to the presence of multiple tangible body macrophages. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVClassical Burkitt Lymphoma

Professional guidelines

PubMed

Smyth L, Browne PV, Conneally E, Flynn C, Hayden P, Jeffers M, O'Brien D, Quinn F, Kelly J, Perera M, Crotty GM, Leahy M, Hennessy B, Jackson F, Ryan M, Vandenberghe E
Ir J Med Sci 2016 Nov;185(4):773-777. Epub 2015 Apr 7 doi: 10.1007/s11845-015-1288-3. PMID: 25843016
Chan TS, Hwang YY, Gill H, Au WY, Leung AY, Tse E, Chim CS, Loong F, Kwong YL
Clin Transplant 2012 Sep-Oct;26(5):679-83. Epub 2012 Feb 10 doi: 10.1111/j.1399-0012.2011.01593.x. PMID: 22324300
Schiffer CA
Semin Hematol 2001 Oct;38(4 Suppl 10):22-6. doi: 10.1016/s0037-1963(01)90040-x. PMID: 11694948

Recent clinical studies

Etiology

Karsten H, Matrisch L, Cichutek S, Fiedler W, Alsdorf W, Block A
Front Immunol 2023;14:1285406. Epub 2023 Nov 27 doi: 10.3389/fimmu.2023.1285406. PMID: 38090582Free PMC Article
Forlenza CJ, Chadburn A, Giulino-Roth L
J Natl Compr Canc Netw 2023 Mar;21(3):323-330. doi: 10.6004/jnccn.2023.7004. PMID: 36898366
Murray PG, Young LS
Blood 2019 Aug 15;134(7):591-596. Epub 2019 Jun 11 doi: 10.1182/blood.2019000568. PMID: 31186275
Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Müller-Hermelink HK, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES, Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, Connors JM, Smeland EB, Kvaloy S, Holte H, Fisher RI, Miller TP, Montserrat E, Wilson WH, Bahl M, Zhao H, Yang L, Powell J, Simon R, Chan WC, Staudt LM; Lymphoma/Leukemia Molecular Profiling Project
N Engl J Med 2006 Jun 8;354(23):2431-42. doi: 10.1056/NEJMoa055759. PMID: 16760443
Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF, Bernd HW, Cogliatti SB, Dierlamm J, Feller AC, Hansmann ML, Haralambieva E, Harder L, Hasenclever D, Kühn M, Lenze D, Lichter P, Martin-Subero JI, Möller P, Müller-Hermelink HK, Ott G, Parwaresch RM, Pott C, Rosenwald A, Rosolowski M, Schwaenen C, Stürzenhofecker B, Szczepanowski M, Trautmann H, Wacker HH, Spang R, Loeffler M, Trümper L, Stein H, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe
N Engl J Med 2006 Jun 8;354(23):2419-30. doi: 10.1056/NEJMoa055351. PMID: 16760442

Diagnosis

Woroniecka R, Rymkiewicz G, Szafron LM, Blachnio K, Szafron LA, Bystydzienski Z, Pienkowska-Grela B, Borkowska K, Rygier J, Kotyl A, Malawska N, Wojtkowska K, Parada J, Borysiuk A, Murcia Pienkowski V, Rydzanicz M, Grygalewicz B
PLoS One 2022;17(2):e0263980. Epub 2022 Feb 15 doi: 10.1371/journal.pone.0263980. PMID: 35167621Free PMC Article
Auerbach A, Schmieg JJ, Aguilera NS
Head Neck Pathol 2021 Mar;15(1):41-58. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01257-6. PMID: 33723759Free PMC Article
Choi WT, Gill RM
Surg Pathol Clin 2018 Jun;11(2):389-402. Epub 2018 Mar 21 doi: 10.1016/j.path.2018.02.003. PMID: 29751882
Taylor J, Xiao W, Abdel-Wahab O
Blood 2017 Jul 27;130(4):410-423. Epub 2017 Jun 9 doi: 10.1182/blood-2017-02-734541. PMID: 28600336Free PMC Article
Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Müller-Hermelink HK, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES, Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, Connors JM, Smeland EB, Kvaloy S, Holte H, Fisher RI, Miller TP, Montserrat E, Wilson WH, Bahl M, Zhao H, Yang L, Powell J, Simon R, Chan WC, Staudt LM; Lymphoma/Leukemia Molecular Profiling Project
N Engl J Med 2006 Jun 8;354(23):2431-42. doi: 10.1056/NEJMoa055759. PMID: 16760443

Therapy

Forlenza CJ, Chadburn A, Giulino-Roth L
J Natl Compr Canc Netw 2023 Mar;21(3):323-330. doi: 10.6004/jnccn.2023.7004. PMID: 36898366
Kroonen JS, de Graaf IJ, Kumar S, Remst DFG, Wouters AK, Heemskerk MHM, Vertegaal ACO
Leukemia 2023 Apr;37(4):864-876. Epub 2023 Feb 15 doi: 10.1038/s41375-023-01838-8. PMID: 36792656Free PMC Article
Castelli R, Schiavon R, Preti C, Ferraris L
Cardiovasc Hematol Disord Drug Targets 2020;20(3):175-180. doi: 10.2174/1871529X20666200415121009. PMID: 32294049Free PMC Article
Perkins AS, Friedberg JW
Hematology Am Soc Hematol Educ Program 2008:341-8. doi: 10.1182/asheducation-2008.1.341. PMID: 19074108
Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Müller-Hermelink HK, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES, Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, Connors JM, Smeland EB, Kvaloy S, Holte H, Fisher RI, Miller TP, Montserrat E, Wilson WH, Bahl M, Zhao H, Yang L, Powell J, Simon R, Chan WC, Staudt LM; Lymphoma/Leukemia Molecular Profiling Project
N Engl J Med 2006 Jun 8;354(23):2431-42. doi: 10.1056/NEJMoa055759. PMID: 16760443

Prognosis

Karsten H, Matrisch L, Cichutek S, Fiedler W, Alsdorf W, Block A
Front Immunol 2023;14:1285406. Epub 2023 Nov 27 doi: 10.3389/fimmu.2023.1285406. PMID: 38090582Free PMC Article
Taylor J, Xiao W, Abdel-Wahab O
Blood 2017 Jul 27;130(4):410-423. Epub 2017 Jun 9 doi: 10.1182/blood-2017-02-734541. PMID: 28600336Free PMC Article
de Leval L, Hasserjian RP
Hematol Oncol Clin North Am 2009 Aug;23(4):791-827. doi: 10.1016/j.hoc.2009.04.004. PMID: 19577170
Perkins AS, Friedberg JW
Hematology Am Soc Hematol Educ Program 2008:341-8. doi: 10.1182/asheducation-2008.1.341. PMID: 19074108
Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF, Bernd HW, Cogliatti SB, Dierlamm J, Feller AC, Hansmann ML, Haralambieva E, Harder L, Hasenclever D, Kühn M, Lenze D, Lichter P, Martin-Subero JI, Möller P, Müller-Hermelink HK, Ott G, Parwaresch RM, Pott C, Rosenwald A, Rosolowski M, Schwaenen C, Stürzenhofecker B, Szczepanowski M, Trautmann H, Wacker HH, Spang R, Loeffler M, Trümper L, Stein H, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe
N Engl J Med 2006 Jun 8;354(23):2419-30. doi: 10.1056/NEJMoa055351. PMID: 16760442

Clinical prediction guides

Kroonen JS, de Graaf IJ, Kumar S, Remst DFG, Wouters AK, Heemskerk MHM, Vertegaal ACO
Leukemia 2023 Apr;37(4):864-876. Epub 2023 Feb 15 doi: 10.1038/s41375-023-01838-8. PMID: 36792656Free PMC Article
Argirion I, Pfeiffer RM, Proietti C, Coghill AE, Yu KJ, Middeldorp JM, Sarathkumara YD, Hsu WL, Chien YC, Lou PJ, Wang CP, Rothman N, Lan Q, Chen CJ, Mbulaiteye SM, Jarrett RF, Glimelius I, Smedby KE, Hjalgrim H, Hildesheim A, Doolan DL, Liu Z
Cancer Epidemiol Biomarkers Prev 2023 May 1;32(5):687-696. doi: 10.1158/1055-9965.EPI-22-0452. PMID: 36788424Free PMC Article
Satou A, Nakamura S
Cancer Med 2021 Oct;10(19):6777-6785. Epub 2021 Aug 13 doi: 10.1002/cam4.4198. PMID: 34387382Free PMC Article
Castelli R, Schiavon R, Preti C, Ferraris L
Cardiovasc Hematol Disord Drug Targets 2020;20(3):175-180. doi: 10.2174/1871529X20666200415121009. PMID: 32294049Free PMC Article
Linke-Serinsöz E, Fend F, Quintanilla-Martinez L
Semin Diagn Pathol 2017 Jul;34(4):352-363. Epub 2017 Apr 7 doi: 10.1053/j.semdp.2017.04.003. PMID: 28506687

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