U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Adult central nervous system germinoma

MedGen UID:
234581
Concept ID:
C1370504
Neoplastic Process
Synonyms: Adult Central Nervous System Germinoma; adult central nervous system germinoma; Adult CNS Germinoma; adult CNS germinoma; central nervous system germinoma of adults; Germinoma of Adult Central Nervous System; germinoma of adult central nervous system; Germinoma of Adult CNS; germinoma of adult CNS; Germinoma of the Adult Central Nervous System; germinoma of the adult central nervous system; Germinoma of the Adult CNS; germinoma of the adult CNS
 
Monarch Initiative: MONDO:0004383

Definition

A central nervous system germinoma that occurs in an adult. [from MONDO]

Professional guidelines

PubMed

Stephens S, Kuchel A, Cheuk R, Alexander H, Robertson T, Rajah T, Tran Q, Inglis PL
J Clin Neurosci 2021 Aug;90:1-7. Epub 2021 May 21 doi: 10.1016/j.jocn.2021.05.006. PMID: 34275531
McClelland S 3rd, Jaboin JJ
Int J Radiat Oncol Biol Phys 2019 Aug 1;104(5):967-968. doi: 10.1016/j.ijrobp.2018.03.040. PMID: 31327425
Fujimaki T
J Child Neurol 2009 Nov;24(11):1439-45. doi: 10.1177/0883073809342127. PMID: 19841431

Recent clinical studies

Etiology

Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Bartels U, Onar-Thomas A, Patel SK, Shaw D, Fangusaro J, Dhall G, Souweidane M, Bhatia A, Embry L, Trask CL, Murphy ES, MacDonald S, Wu S, Boyett JM, Leary S, Fouladi M, Gajjar A, Khatua S
Neuro Oncol 2022 Jun 1;24(6):974-983. doi: 10.1093/neuonc/noab270. PMID: 34850169Free PMC Article
Wildeman ME, Shepard MJ, Oldfield EH, Lopes MBS
J Neuropathol Exp Neurol 2018 Apr 1;77(4):312-316. doi: 10.1093/jnen/nly008. PMID: 29415126
Agrawal M, Uppin MS, Patibandla MR, Bhattacharjee S, Panigrahi MK, Saradhi V, Rani JY, Purohit AK, Challa S
Neurol India 2010 Nov-Dec;58(6):841-6. doi: 10.4103/0028-3886.73740. PMID: 21150046
Capra M, Hargrave D, Bartels U, Hyder D, Huang A, Bouffet E
Eur J Cancer 2003 Dec;39(18):2643-50. doi: 10.1016/j.ejca.2003.09.003. PMID: 14642926

Diagnosis

La Corte E, Martinoni M
N Engl J Med 2021 Dec 23;385(26):e94. doi: 10.1056/NEJMicm2031597. PMID: 34936742
Minter DJ, Richie M, Kumthekar P, Hollander H
N Engl J Med 2021 Apr 1;384(13):1262-1267. doi: 10.1056/NEJMcps2028560. PMID: 33789016
Shankar S, Wu X, Kalra VB, Huttner AJ, Malhotra A
J Clin Neurosci 2016 Sep;31:192-5. Epub 2016 Apr 2 doi: 10.1016/j.jocn.2016.02.013. PMID: 27050919
Dufour C, Guerrini-Rousseau L, Grill J
Curr Opin Oncol 2014 Nov;26(6):622-6. doi: 10.1097/CCO.0000000000000140. PMID: 25233069
Fujimaki T
J Child Neurol 2009 Nov;24(11):1439-45. doi: 10.1177/0883073809342127. PMID: 19841431

Therapy

Bartels U, Onar-Thomas A, Patel SK, Shaw D, Fangusaro J, Dhall G, Souweidane M, Bhatia A, Embry L, Trask CL, Murphy ES, MacDonald S, Wu S, Boyett JM, Leary S, Fouladi M, Gajjar A, Khatua S
Neuro Oncol 2022 Jun 1;24(6):974-983. doi: 10.1093/neuonc/noab270. PMID: 34850169Free PMC Article
McClelland S 3rd, Jaboin JJ
Int J Radiat Oncol Biol Phys 2019 Aug 1;104(5):967-968. doi: 10.1016/j.ijrobp.2018.03.040. PMID: 31327425
Leroy R, Benahmed N, Hulstaert F, Van Damme N, De Ruysscher D
Int J Radiat Oncol Biol Phys 2016 May 1;95(1):267-278. Epub 2015 Oct 17 doi: 10.1016/j.ijrobp.2015.10.025. PMID: 27084646
Tseng CK, Tsang NM, Jaing TH, Liau CT, Wu CT, Lin KL
J Pediatr Hematol Oncol 2011 May;33(4):e138-42. doi: 10.1097/MPH.0b013e31820d0c69. PMID: 21516012
Borg M
Med Pediatr Oncol 2003 Jun;40(6):367-74. doi: 10.1002/mpo.10285. PMID: 12692804

Prognosis

Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Kumar N, Madan R, Dracham CB, Khosla D, Das N, Dey T, Elangovan A, Tripathi M, Gupta K, Ahuja CK, Kapoor R
Clin Neurol Neurosurg 2021 Mar;202:106481. Epub 2021 Jan 13 doi: 10.1016/j.clineuro.2021.106481. PMID: 33508649
Dufour C, Guerrini-Rousseau L, Grill J
Curr Opin Oncol 2014 Nov;26(6):622-6. doi: 10.1097/CCO.0000000000000140. PMID: 25233069
Tseng CK, Tsang NM, Jaing TH, Liau CT, Wu CT, Lin KL
J Pediatr Hematol Oncol 2011 May;33(4):e138-42. doi: 10.1097/MPH.0b013e31820d0c69. PMID: 21516012
Agrawal M, Uppin MS, Patibandla MR, Bhattacharjee S, Panigrahi MK, Saradhi V, Rani JY, Purohit AK, Challa S
Neurol India 2010 Nov-Dec;58(6):841-6. doi: 10.4103/0028-3886.73740. PMID: 21150046

Clinical prediction guides

Fernández-Rodríguez LJ, Maldonado-Pijoan X
Cancer Rep (Hoboken) 2022 Sep;5(9):e1611. Epub 2022 Mar 28 doi: 10.1002/cnr2.1611. PMID: 35347869Free PMC Article
Bartels U, Onar-Thomas A, Patel SK, Shaw D, Fangusaro J, Dhall G, Souweidane M, Bhatia A, Embry L, Trask CL, Murphy ES, MacDonald S, Wu S, Boyett JM, Leary S, Fouladi M, Gajjar A, Khatua S
Neuro Oncol 2022 Jun 1;24(6):974-983. doi: 10.1093/neuonc/noab270. PMID: 34850169Free PMC Article
Satomi K, Takami H, Fukushima S, Yamashita S, Matsushita Y, Nakazato Y, Suzuki T, Tanaka S, Mukasa A, Saito N, Kanamori M, Kumabe T, Tominaga T, Kobayashi K, Nagane M, Iuchi T, Yoshimoto K, Tamura K, Maehara T, Sakai K, Sugiyama K, Yokogami K, Takeshima H, Nonaka M, Asai A, Ushijima T, Matsutani M, Nishikawa R, Ichimura K
Neuro Oncol 2022 May 4;24(5):834-846. doi: 10.1093/neuonc/noab246. PMID: 34698864Free PMC Article
Kumar N, Madan R, Dracham CB, Khosla D, Das N, Dey T, Elangovan A, Tripathi M, Gupta K, Ahuja CK, Kapoor R
Clin Neurol Neurosurg 2021 Mar;202:106481. Epub 2021 Jan 13 doi: 10.1016/j.clineuro.2021.106481. PMID: 33508649
Wildeman ME, Shepard MJ, Oldfield EH, Lopes MBS
J Neuropathol Exp Neurol 2018 Apr 1;77(4):312-316. doi: 10.1093/jnen/nly008. PMID: 29415126

Recent systematic reviews

Zhang Y, Wang L, Ma W, Pan H, Wang R, Zhu H, Yao Y
Front Endocrinol (Lausanne) 2021;12:763609. Epub 2021 Nov 10 doi: 10.3389/fendo.2021.763609. PMID: 34858336Free PMC Article
Leroy R, Benahmed N, Hulstaert F, Van Damme N, De Ruysscher D
Int J Radiat Oncol Biol Phys 2016 May 1;95(1):267-278. Epub 2015 Oct 17 doi: 10.1016/j.ijrobp.2015.10.025. PMID: 27084646
Abraham A, Drory VE
J Neurol 2013 Jul;260(7):1802-6. Epub 2013 Mar 5 doi: 10.1007/s00415-013-6881-7. PMID: 23463367

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...