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Colorectal juvenile polyp

MedGen UID:
235116
•Concept ID:
C1377708
•
Neoplastic Process
Synonyms: Colorectal Juvenile Polyp; colorectal juvenile polyp; Colorectal Retention Polyp; colorectal retention polyp; Juvenile Polyp of Large Bowel; juvenile polyp of large bowel; Juvenile Polyp of the Large Bowel; juvenile polyp of the large bowel; Juvenile polyps of large bowel; Large Bowel Juvenile Polyp; large bowel juvenile polyp; Large Intestinal Juvenile Polyp; large intestinal juvenile polyp; Retention polyps of large bowel
SNOMED CT: Retention polyps of large bowel (9273005); Juvenile polyps of large bowel (9273005)
 
Monarch Initiative: MONDO:0006161

Definition

A non-neoplastic hamartomatous polyp that arises from the colon and rectum. It is characterized by the presence of tortuous and cystically dilated glands, edematous changes, and inflammation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal juvenile polyp

Professional guidelines

PubMed

Genotype-defined cancer risk in juvenile polyposis syndrome.
Aytac E, Sulu B, Heald B, O'Malley M, LaGuardia L, Remzi FH, Kalady MF, Burke CA, Church JM
Br J Surg 2015 Jan;102(1):114-8. Epub 2014 Nov 12 doi: 10.1002/bjs.9693. PMID: 25389115
The differential diagnosis and surveillance of hereditary gastrointestinal polyposis syndromes.
Aretz S
Dtsch Arztebl Int 2010 Mar;107(10):163-73. Epub 2010 Mar 12 doi: 10.3238/arztebl.2010.0163. PMID: 20358032Free PMC Article
Genetic testing for polyposis: practical and ethical aspects.
Järvinen HJ
Gut 2003 May;52 Suppl 2(Suppl 2):ii19-22. doi: 10.1136/gut.52.suppl_2.ii19. PMID: 12651878Free PMC Article

Recent clinical studies

Etiology

Expression of BMP2, TLR3, TLR4 and COX2 in colorectal polyps, adenoma and adenocarcinoma.
Xiang L, Wang S, Jin X, Duan W, Ding X, Zheng C
Mol Med Rep 2012 Nov;6(5):973-6. Epub 2012 Aug 24 doi: 10.3892/mmr.2012.1046. PMID: 22923219

Diagnosis

JUVENILE POLYP IN ADULTS.
Popović M, Knežević A, Dolinaj Škopelja J, Đolai M
Acta Clin Croat 2022 Aug;61(2):354-358. doi: 10.20471/acc.2022.61.02.23. PMID: 36818922Free PMC Article
Diagnosis and management of a solitary colorectal juvenile polyp in an adult during follow-up for ulcerative colitis: A case report.
Chen YW, Tu JF, Shen WJ, Chen WY, Dong J
World J Gastroenterol 2020 Feb 28;26(8):877-882. doi: 10.3748/wjg.v26.i8.877. PMID: 32148384Free PMC Article

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