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Ganglion cyst

MedGen UID:
263633
Concept ID:
C1258666
Anatomical Abnormality
Synonyms: Cyst, Ganglion; Cyst, Ganglionic; Cyst, Myxoid; Cysts, Ganglion; Cysts, Ganglionic; Cysts, Myxoid; Ganglion; Ganglion Cyst; Ganglion Cysts; Ganglionic Cyst; Ganglionic Cysts; Ganglions; Myxoid Cyst; Myxoid Cysts
SNOMED CT: Ganglion cyst (71307009); Myxoid cyst (71307009); Ganglion (71307009); Benign cystic mucinous tumor (71307009); Mucous cyst of skin (78435003); Ganglion cyst (445008009)

Definition

Nodular tumor-like lesions or mucoid flesh, arising from tendon sheaths, LIGAMENTS, or JOINT CAPSULE, especially of the hands, wrists, or feet. They are not true cysts as they lack epithelial wall. They are distinguished from SYNOVIAL CYSTS by the lack of communication with a joint cavity or the SYNOVIAL MEMBRANE. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGanglion cyst

Professional guidelines

PubMed

Mei Z, Lei W, Huang D, Ma W, Pan G, Ni L, Han Z
Z Orthop Unfall 2024 Apr;162(2):143-148. Epub 2022 Oct 20 doi: 10.1055/a-1938-8449. PMID: 36265495
Scarborough A, MacFarlane RJ, Mehta N, Smith GD
Br J Hosp Med (Lond) 2020 Sep 2;81(9):1-9. Epub 2020 Sep 25 doi: 10.12968/hmed.2020.0298. PMID: 32990073
Freehill MT, Shi LL, Tompson JD, Warner JJ
Phys Sportsmed 2012 Feb;40(1):72-83. doi: 10.3810/psm.2012.02.1953. PMID: 22508253

Recent clinical studies

Etiology

Mei Z, Lei W, Huang D, Ma W, Pan G, Ni L, Han Z
Z Orthop Unfall 2024 Apr;162(2):143-148. Epub 2022 Oct 20 doi: 10.1055/a-1938-8449. PMID: 36265495
Lenartowicz KA, Murthy NK, Desy NM, De La Pena NM, Wolf AS, Wilson TJ, Amrami KK, Spinner RJ
Acta Neurochir (Wien) 2022 Oct;164(10):2689-2698. Epub 2022 Jul 25 doi: 10.1007/s00701-022-05311-w. PMID: 35877047
Bram JT, Falk DP, Chang B, Ty JM, Lin IC, Fazal FZ, Shah AS
J Hand Surg Am 2021 Dec;46(12):1122.e1-1122.e9. Epub 2021 Apr 20 doi: 10.1016/j.jhsa.2021.02.026. PMID: 33888379
Meyerson J, Pan YL, Spaeth M, Pearson G
Hand (N Y) 2019 Jul;14(4):445-448. Epub 2018 Jan 9 doi: 10.1177/1558944717751195. PMID: 29310457Free PMC Article
Desy NM, Wang H, Elshiekh MA, Tanaka S, Choi TW, Howe BM, Spinner RJ
J Neurosurg 2016 Sep;125(3):615-30. Epub 2016 Jan 22 doi: 10.3171/2015.9.JNS141368. PMID: 26799306

Diagnosis

Crouser N, Wright J, DiBartola A, Flanigan D, Duerr R
J Knee Surg 2024 Jan;37(2):149-157. Epub 2022 Dec 20 doi: 10.1055/a-2001-6764. PMID: 36539213
Mei Z, Lei W, Huang D, Ma W, Pan G, Ni L, Han Z
Z Orthop Unfall 2024 Apr;162(2):143-148. Epub 2022 Oct 20 doi: 10.1055/a-1938-8449. PMID: 36265495
Meyerson J, Pan YL, Spaeth M, Pearson G
Hand (N Y) 2019 Jul;14(4):445-448. Epub 2018 Jan 9 doi: 10.1177/1558944717751195. PMID: 29310457Free PMC Article
Clavert P, Thomazeau H
Orthop Traumatol Surg Res 2014 Dec;100(8 Suppl):S409-11. Epub 2014 Oct 25 doi: 10.1016/j.otsr.2014.10.002. PMID: 25454727
Romeo AA, Rotenberg DD, Bach BR Jr
J Am Acad Orthop Surg 1999 Nov-Dec;7(6):358-67. doi: 10.5435/00124635-199911000-00002. PMID: 11497489

Therapy

Pohl NB, Derector E, Rivlin M, Bachoura A, Tosti R, Kachooei AR, Beredjiklian PK, Fletcher DJ
Hand Surg Rehabil 2024 Jun;43(3):101723. Epub 2024 May 21 doi: 10.1016/j.hansur.2024.101723. PMID: 38782361
Meyerson J, Pan YL, Spaeth M, Pearson G
Hand (N Y) 2019 Jul;14(4):445-448. Epub 2018 Jan 9 doi: 10.1177/1558944717751195. PMID: 29310457Free PMC Article
Jenkinson HA, Wilmas KM, Silapunt S
Dermatol Surg 2017 Nov;43(11):1313-1320. doi: 10.1097/DSS.0000000000001143. PMID: 28430735
Ju BL, Weber KL, Khoury V
J Foot Ankle Surg 2017 Jan-Feb;56(1):153-157. Epub 2016 Jun 4 doi: 10.1053/j.jfas.2016.04.015. PMID: 27267413
Freehill MT, Shi LL, Tompson JD, Warner JJ
Phys Sportsmed 2012 Feb;40(1):72-83. doi: 10.3810/psm.2012.02.1953. PMID: 22508253

Prognosis

Daliri M, Khosravi F, Shakeri MT, Ebrahimzadeh MH, Moradi A
J Orthop Surg Res 2023 Aug 26;18(1):626. doi: 10.1186/s13018-023-04108-6. PMID: 37633940Free PMC Article
Rana S, Pradhan A, Casaos J, Mozaffari K, Ghodrati F, Sugimoto B, Yang I, Nagasawa DT
J Neurol Sci 2023 Feb 15;445:120539. Epub 2022 Dec 28 doi: 10.1016/j.jns.2022.120539. PMID: 36638603
Van Overstraeten L, Camus EJ, Moungondo F, Schuind F
Hand Clin 2022 Feb;38(1):101-107. doi: 10.1016/j.hcl.2021.08.011. PMID: 34802602
Bram JT, Falk DP, Chang B, Ty JM, Lin IC, Fazal FZ, Shah AS
J Hand Surg Am 2022 Nov;47(11):1119.e1-1119.e8. Epub 2021 Oct 11 doi: 10.1016/j.jhsa.2021.09.001. PMID: 34649743
Bram JT, Falk DP, Chang B, Ty JM, Lin IC, Fazal FZ, Shah AS
J Hand Surg Am 2021 Dec;46(12):1122.e1-1122.e9. Epub 2021 Apr 20 doi: 10.1016/j.jhsa.2021.02.026. PMID: 33888379

Clinical prediction guides

Goller SS, Kajdi GW, Feuerriegel GC, Sutter R
Eur Radiol 2024 Dec;34(12):7869-7877. Epub 2024 Jul 3 doi: 10.1007/s00330-024-10884-4. PMID: 38958696Free PMC Article
Mei Z, Lei W, Huang D, Ma W, Pan G, Ni L, Han Z
Z Orthop Unfall 2024 Apr;162(2):143-148. Epub 2022 Oct 20 doi: 10.1055/a-1938-8449. PMID: 36265495
Zheng T, Huang X, Yang Y, Li B, Li F, Li Z
Orthop Surg 2023 Feb;15(2):480-487. Epub 2022 Dec 5 doi: 10.1111/os.13576. PMID: 36465035Free PMC Article
Bram JT, Falk DP, Chang B, Ty JM, Lin IC, Fazal FZ, Shah AS
J Hand Surg Am 2021 Dec;46(12):1122.e1-1122.e9. Epub 2021 Apr 20 doi: 10.1016/j.jhsa.2021.02.026. PMID: 33888379
Tie K, Wang H, Zhao X, Tan Y, Qin J, Chen L
J Orthop Surg Res 2018 Apr 13;13(1):84. doi: 10.1186/s13018-018-0798-x. PMID: 29653540Free PMC Article

Recent systematic reviews

Krishnan P, Dineshkumar T, Divya B, Krishnan R, Rameshkumar A
Ann Diagn Pathol 2023 Dec;67:152212. Epub 2023 Sep 20 doi: 10.1016/j.anndiagpath.2023.152212. PMID: 37748213
Rana S, Pradhan A, Casaos J, Mozaffari K, Ghodrati F, Sugimoto B, Yang I, Nagasawa DT
J Neurol Sci 2023 Feb 15;445:120539. Epub 2022 Dec 28 doi: 10.1016/j.jns.2022.120539. PMID: 36638603
Lenartowicz KA, Wolf AS, Desy NM, Strakowski JA, Amrami KK, Spinner RJ
World Neurosurg 2022 Oct;166:e968-e979. Epub 2022 Aug 8 doi: 10.1016/j.wneu.2022.08.005. PMID: 35953037
Oliver JD, Boczar D, Huayllani MT, Restrepo DJ, Sisti A, Manrique OJ, Broer PN, Forte AJ
Ann Plast Surg 2019 Dec;83(6):e77-e84. doi: 10.1097/SAP.0000000000002004. PMID: 31599787
Desy NM, Wang H, Elshiekh MA, Tanaka S, Choi TW, Howe BM, Spinner RJ
J Neurosurg 2016 Sep;125(3):615-30. Epub 2016 Jan 22 doi: 10.3171/2015.9.JNS141368. PMID: 26799306

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