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Epiglottis neoplasm

MedGen UID:
266215
•Concept ID:
C1290353
•
Neoplastic Process
Synonyms: Epiglottic Neoplasm; epiglottic neoplasm; Epiglottic Tumor; epiglottic tumor; epiglottic tumour; Epiglottis Neoplasm; epiglottis neoplasm; epiglottis neoplasm (disease); Epiglottis Tumor; epiglottis tumor; Epiglottis tumor; Epiglottis tumour; epiglottis tumour; Neoplasm of epiglottis; Neoplasm of Epiglottis; neoplasm of epiglottis; neoplasm of Epiglottis; Neoplasm of the Epiglottis; neoplasm of the Epiglottis; Tumor of Epiglottis; tumor of Epiglottis; tumor of epiglottis; Tumor of the Epiglottis; tumor of the Epiglottis; tumour of epiglottis; tumour of Epiglottis; tumour of the Epiglottis
SNOMED CT: Neoplasm of epiglottis (126699008)
 
Monarch Initiative: MONDO:0004109

Definition

A benign or malignant neoplasm that affects the epiglottis. [from NCI]

Professional guidelines

PubMed

Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Surgery and irradiation in the treatment of squamous cell cancer of the supraglottic larynx.
Flynn MB, Jesse RH, Lindberg RD
Am J Surg 1972 Oct;124(4):477-81. doi: 10.1016/0002-9610(72)90070-0. PMID: 5076161
Management of pre-epiglottic cysts: a report of nine cases.
Keenleyside HB, Greenway RE
Can Med Assoc J 1968 Oct 5;99(13):645-9. PMID: 5685510Free PMC Article

Recent clinical studies

Etiology

Isoprognostic functional CT map for open partial horizontal laryngectomy.
Bertolin A, Varago C, Salemi M, Piccoli G, Nicolai P, Lionello M
Eur Arch Otorhinolaryngol 2024 Jun;281(6):3051-3060. Epub 2024 Mar 30 doi: 10.1007/s00405-024-08596-y. PMID: 38554153
Videofluoroscopic Measures of Swallowing After Partial Epiglottidectomy for Dysphagia.
Chung HR, Reddy NK, Smith AF, Chhetri DK
Otolaryngol Head Neck Surg 2023 Aug;169(2):317-324. Epub 2023 Feb 5 doi: 10.1002/ohn.294. PMID: 36939459
Chondrosarcoma of the Epiglottis: A Case Report and Literature Review.
Choi J, Dharmarajan H, Victores A, Wenaas A, Ongkasuwan J
J Voice 2018 Jul;32(4):484-487. Epub 2017 Aug 16 doi: 10.1016/j.jvoice.2017.07.014. PMID: 28822621
Vallecular cysts in newborns and young infants.
Gutiérrez JP, Berkowitz RG, Robertson CF
Pediatr Pulmonol 1999 Apr;27(4):282-5. doi: 10.1002/(sici)1099-0496(199904)27:4<282::aid-ppul10>3.0.co;2-g. PMID: 10230929
Median labiomandibular glossotomy.
Wessberg GA, Hill SC, McBride KL
Int J Oral Surg 1981 Oct;10(5):333-7. doi: 10.1016/s0300-9785(81)80030-0. PMID: 6807920

Diagnosis

Pallister-Hall syndrome, GLI3, and kidney malformation.
McClelland K, Li W, Rosenblum ND
Am J Med Genet C Semin Med Genet 2022 Sep;190(3):264-278. Epub 2022 Sep 27 doi: 10.1002/ajmg.c.31999. PMID: 36165461
Schwannoma of the Supraglottis.
Gupta R, Azhdam AM, Borrelli M
Ear Nose Throat J 2021 Sep;100(6_suppl):879S-880S. Epub 2021 Jun 10 doi: 10.1177/01455613211018586. PMID: 34112006
Pallister-Hall syndrome in a 2-years-old girl.
Nocoń-Bohusz J, Basiak A, Bosak-Prus M, Noczyńska A
Pediatr Endocrinol Diabetes Metab 2019;25(4):208-211. doi: 10.5114/pedm.2019.89253. PMID: 32270976
Cricoid-based extramedullary plasmocytoma.
Pichi B, Terenzi V, Covello R, Spriano G
J Craniofac Surg 2011 Nov;22(6):2361-3. doi: 10.1097/SCS.0b013e318231e56d. PMID: 22134279
Bifid epiglottis.
Goldenberg JD, Holinger LD, Bressler FJ, Hutchinson LR
Ann Otol Rhinol Laryngol 1996 Feb;105(2):155-7. doi: 10.1177/000348949610500211. PMID: 8659937

Therapy

Pleomorphic adenoma of the epiglottis.
Alzate Amaya F, Invencio da Costa L, Álvarez-Buylla Blanco M
Acta Otorrinolaringol Esp (Engl Ed) 2019 Nov-Dec;70(6):376-377. Epub 2018 Dec 24 doi: 10.1016/j.otorri.2018.07.002. PMID: 30591211
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Nasogastric Tube Syndrome: A Diagnostic Dilemma.
Nayak G, Virk RS, Singh M, Singh M
J Bronchology Interv Pulmonol 2018 Oct;25(4):343-345. doi: 10.1097/LBR.0000000000000507. PMID: 29771772
Could laser-assisted dissection of the pre-epiglottic space affect functional outcome after ESL?
Bertolin A, Lionello M, Russo S, Rizzotto G, Lucioni M
Laryngoscope 2018 Jun;128(6):1371-1378. Epub 2017 Oct 27 doi: 10.1002/lary.26961. PMID: 29076556
Aspergillus epiglottitis.
Bolivar R, Gomez LG, Luna M, Hopfer R, Bodey GP
Cancer 1983 Jan 15;51(2):367-70. doi: 10.1002/1097-0142(19830115)51:2<367::aid-cncr2820510234>3.0.co;2-g. PMID: 6401587

Prognosis

Pallister-Hall syndrome in a 2-years-old girl.
Nocoń-Bohusz J, Basiak A, Bosak-Prus M, Noczyńska A
Pediatr Endocrinol Diabetes Metab 2019;25(4):208-211. doi: 10.5114/pedm.2019.89253. PMID: 32270976
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Epiglottoplasty technique in endoscopic partial laryngectomy.
Moulin M, Righini CA, Castellanos PF, Atallah I
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Jun;135(3):197-199. Epub 2018 Jan 12 doi: 10.1016/j.anorl.2017.12.003. PMID: 29338941
The laryngeal saccule: clinical significance.
Porter PW, Vilensky JA
Clin Anat 2012 Jul;25(5):647-9. Epub 2011 Dec 12 doi: 10.1002/ca.22015. PMID: 22162142
Cricoid-based extramedullary plasmocytoma.
Pichi B, Terenzi V, Covello R, Spriano G
J Craniofac Surg 2011 Nov;22(6):2361-3. doi: 10.1097/SCS.0b013e318231e56d. PMID: 22134279

Clinical prediction guides

Isoprognostic functional CT map for open partial horizontal laryngectomy.
Bertolin A, Varago C, Salemi M, Piccoli G, Nicolai P, Lionello M
Eur Arch Otorhinolaryngol 2024 Jun;281(6):3051-3060. Epub 2024 Mar 30 doi: 10.1007/s00405-024-08596-y. PMID: 38554153
Videofluoroscopic Measures of Swallowing After Partial Epiglottidectomy for Dysphagia.
Chung HR, Reddy NK, Smith AF, Chhetri DK
Otolaryngol Head Neck Surg 2023 Aug;169(2):317-324. Epub 2023 Feb 5 doi: 10.1002/ohn.294. PMID: 36939459
Cellular angiofibroma in the hypopharynx: A case report.
Liu Y, Xu Y, Wang Q, Chen Q
Medicine (Baltimore) 2019 Dec;98(50):e18385. doi: 10.1097/MD.0000000000018385. PMID: 31852154Free PMC Article
Chondrosarcoma of the Epiglottis: A Case Report and Literature Review.
Choi J, Dharmarajan H, Victores A, Wenaas A, Ongkasuwan J
J Voice 2018 Jul;32(4):484-487. Epub 2017 Aug 16 doi: 10.1016/j.jvoice.2017.07.014. PMID: 28822621
Determination of biometric measures to evaluate patient suitability for transoral robotic surgery.
Arora A, Kotecha J, Acharya A, Garas G, Darzi A, Davies DC, Tolley N
Head Neck 2015 Sep;37(9):1254-60. Epub 2014 Oct 29 doi: 10.1002/hed.23739. PMID: 24800962

Recent systematic reviews

Cancer of the Larynx-20-Year Comparative Survival and Mortality Analysis by Age, Sex, Race, Stage, Grade, Cohort Entry Time-Period, Disease Duration and ICD-O-3 Topographic Primary Sites-Codes C32.0-9: A Systematic Review of 43,103 Cases for Diagnosis Years 1975-2017: (NCI SEER*Stat 8.3.9).
Milano AF
J Insur Med 2024 Jul 1;51(2):92-110. doi: 10.17849/insm-51-2-92-110.1. PMID: 39266004
Features related to temporary tracheotomy in patients undergoing Transoral Robotic Surgery (TORS) for supraglottic squamous cell cancer of the larynx: A systematic review.
Chiari F, Guarino P, Di Martino G, Caporale CD, Presutti L, Molteni G
Am J Otolaryngol 2024 Sep-Oct;45(5):104436. Epub 2024 Jul 25 doi: 10.1016/j.amjoto.2024.104436. PMID: 39068815
Laryngeal chondrosarcoma: A systematic review of 592 cases.
Chin OY, Dubal PM, Sheikh AB, Unsal AA, Park RC, Baredes S, Eloy JA
Laryngoscope 2017 Feb;127(2):430-439. Epub 2016 Jun 12 doi: 10.1002/lary.26068. PMID: 27291822
Laryngeal schwannoma: a systematic review.
Wong BLK, Bathala S, Grant D
Eur Arch Otorhinolaryngol 2017 Jan;274(1):25-34. Epub 2016 Mar 28 doi: 10.1007/s00405-016-4013-6. PMID: 27020268
Management of the clinically negative neck (N0) of supraglottic laryngeal carcinoma: a systematic review.
Goudakos JK, Markou K, Nikolaou A, Themelis C, Vital V
Eur J Surg Oncol 2009 Mar;35(3):223-9. Epub 2008 May 12 doi: 10.1016/j.ejso.2008.04.001. PMID: 18468836

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