U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Peripheral arterial occlusive disease

MedGen UID:
266302
•Concept ID:
C1306889
•
Disease or Syndrome
Synonym: peripheral arterial occlusive disease
SNOMED CT: Peripheral arterial occlusive disease (399957001); PAOD - Peripheral arterial occlusive disease (399957001); Peripheral artery occlusive disease (399957001)

Definition

Disorder caused by the occlusion of the lumen of the peripheral arteries. Causes include atherosclerosis, inflammatory processes, thrombosis, and embolism. The arterial occlusion results in chronic or acute pain usually in the lower limbs due to muscle ischemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral arterial occlusive disease

Professional guidelines

PubMed

Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
Optimal management of infrainguinal arterial occlusive disease.
Pennywell DJ, Tan TW, Zhang WW
Vasc Health Risk Manag 2014;10:599-608. Epub 2014 Oct 24 doi: 10.2147/VHRM.S50779. PMID: 25368519Free PMC Article
Why critical limb ischemia criteria are not applicable to diabetic foot and what the consequences are.
Jörneskog G
Scand J Surg 2012;101(2):114-8. doi: 10.1177/145749691210100207. PMID: 22623444

Recent clinical studies

Etiology

Neutral effects of SGLT2 inhibitors in acute coronary syndromes, peripheral arterial occlusive disease, or ischemic stroke: a meta-analysis of randomized controlled trials.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH, Yeh YH
Cardiovasc Diabetol 2023 Mar 13;22(1):57. doi: 10.1186/s12933-023-01789-5. PMID: 36915157Free PMC Article
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
A systematic review and meta-analysis of hyperbaric oxygen therapy for diabetic foot ulcers with arterial insufficiency.
Brouwer RJ, Lalieu RC, Hoencamp R, van Hulst RA, Ubbink DT
J Vasc Surg 2020 Feb;71(2):682-692.e1. doi: 10.1016/j.jvs.2019.07.082. PMID: 32040434
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Diagnosis

Neutral effects of SGLT2 inhibitors in acute coronary syndromes, peripheral arterial occlusive disease, or ischemic stroke: a meta-analysis of randomized controlled trials.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH, Yeh YH
Cardiovasc Diabetol 2023 Mar 13;22(1):57. doi: 10.1186/s12933-023-01789-5. PMID: 36915157Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Therapy

Neutral effects of SGLT2 inhibitors in acute coronary syndromes, peripheral arterial occlusive disease, or ischemic stroke: a meta-analysis of randomized controlled trials.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH, Yeh YH
Cardiovasc Diabetol 2023 Mar 13;22(1):57. doi: 10.1186/s12933-023-01789-5. PMID: 36915157Free PMC Article
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
A systematic review and meta-analysis of hyperbaric oxygen therapy for diabetic foot ulcers with arterial insufficiency.
Brouwer RJ, Lalieu RC, Hoencamp R, van Hulst RA, Ubbink DT
J Vasc Surg 2020 Feb;71(2):682-692.e1. doi: 10.1016/j.jvs.2019.07.082. PMID: 32040434
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Vascular grafts.
Leon L, Greisler HP
Expert Rev Cardiovasc Ther 2003 Nov;1(4):581-94. doi: 10.1586/14779072.1.4.581. PMID: 15030257

Prognosis

Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
Assessment of aortic pathology and peripheral arterial disease using multidetector computed tomographic angiography.
Lin PH, Bechara C, Kougias P, Huynh TT, LeMaire SA, Coselli JS
Vasc Endovascular Surg 2008 Dec-2009 Jan;42(6):583-98. Epub 2008 Jul 11 doi: 10.1177/1538574408320029. PMID: 18621886
Subintimal angioplasty for peripheral arterial occlusive disease: a systematic review.
Met R, Van Lienden KP, Koelemay MJ, Bipat S, Legemate DA, Reekers JA
Cardiovasc Intervent Radiol 2008 Jul-Aug;31(4):687-97. Epub 2008 Apr 15 doi: 10.1007/s00270-008-9331-7. PMID: 18414946Free PMC Article
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271

Clinical prediction guides

Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
The Association of Periodontitis and Peripheral Arterial Occlusive Disease-A Systematic Review.
Kaschwich M, Behrendt CA, Heydecke G, Bayer A, Debus ES, Seedorf U, Aarabi G
Int J Mol Sci 2019 Jun 15;20(12) doi: 10.3390/ijms20122936. PMID: 31208079Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD000095. doi: 10.1002/14651858.CD000095.pub2. PMID: 23633303Free PMC Article
Assessment of aortic pathology and peripheral arterial disease using multidetector computed tomographic angiography.
Lin PH, Bechara C, Kougias P, Huynh TT, LeMaire SA, Coselli JS
Vasc Endovascular Surg 2008 Dec-2009 Jan;42(6):583-98. Epub 2008 Jul 11 doi: 10.1177/1538574408320029. PMID: 18621886

Recent systematic reviews

A systematic review and meta-analysis of hyperbaric oxygen therapy for diabetic foot ulcers with arterial insufficiency.
Brouwer RJ, Lalieu RC, Hoencamp R, van Hulst RA, Ubbink DT
J Vasc Surg 2020 Feb;71(2):682-692.e1. doi: 10.1016/j.jvs.2019.07.082. PMID: 32040434
Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review.
Hischke S, Rieß HC, Bublitz MK, Kriston L, Schwaneberg T, Härter M, Bertges D, S Debus E, Behrendt CA
Eur J Vasc Endovasc Surg 2019 Nov;58(5):738-745. Epub 2019 Sep 13 doi: 10.1016/j.ejvs.2019.06.029. PMID: 31526633
The Association of Periodontitis and Peripheral Arterial Occlusive Disease-A Systematic Review.
Kaschwich M, Behrendt CA, Heydecke G, Bayer A, Debus ES, Seedorf U, Aarabi G
Int J Mol Sci 2019 Jun 15;20(12) doi: 10.3390/ijms20122936. PMID: 31208079Free PMC Article
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD000095. doi: 10.1002/14651858.CD000095.pub2. PMID: 23633303Free PMC Article
Subintimal angioplasty for peripheral arterial occlusive disease: a systematic review.
Met R, Van Lienden KP, Koelemay MJ, Bipat S, Legemate DA, Reekers JA
Cardiovasc Intervent Radiol 2008 Jul-Aug;31(4):687-97. Epub 2008 Apr 15 doi: 10.1007/s00270-008-9331-7. PMID: 18414946Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...