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Peripheral arterial occlusive disease

MedGen UID:
266302
•Concept ID:
C1306889
•
Disease or Syndrome
Synonym: peripheral arterial occlusive disease
SNOMED CT: Peripheral arterial occlusive disease (399957001); PAOD - Peripheral arterial occlusive disease (399957001); Peripheral artery occlusive disease (399957001)

Definition

Disorder caused by the occlusion of the lumen of the peripheral arteries. Causes include atherosclerosis, inflammatory processes, thrombosis, and embolism. The arterial occlusion results in chronic or acute pain usually in the lower limbs due to muscle ischemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral arterial occlusive disease

Professional guidelines

PubMed

Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
The Diagnosis and Treatment of Peripheral Arterial Vascular Disease.
Lawall H, Huppert P, Espinola-Klein C, Rümenapf G
Dtsch Arztebl Int 2016 Oct 28;113(43):729-736. doi: 10.3238/arztebl.2016.0729. PMID: 27866570Free PMC Article
Optimal management of infrainguinal arterial occlusive disease.
Pennywell DJ, Tan TW, Zhang WW
Vasc Health Risk Manag 2014;10:599-608. Epub 2014 Oct 24 doi: 10.2147/VHRM.S50779. PMID: 25368519Free PMC Article

Recent clinical studies

Etiology

Utility of the cold pressor test to predict future cardiovascular events.
Pouwels S, Van Genderen ME, Kreeftenberg HG, Ribeiro R, Parmar C, Topal B, Celik A, Ugale S
Expert Rev Cardiovasc Ther 2019 Apr;17(4):305-318. Epub 2019 Apr 8 doi: 10.1080/14779072.2019.1598262. PMID: 30916592
Changes in flow-mediated dilatation in patients with femoropopliteal occlusion receiving conservative and invasive treatment.
Pawlaczyk K, Gabriel M, Urbanek T, Dzieciuchowicz Ł, Begier-Krasińska B, Stanisić M, Wachal K, Zieliński M
Kardiol Pol 2016;74(8):772-778. Epub 2016 Mar 11 doi: 10.5603/KP.a2016.0027. PMID: 26965925
New hybrid reformations of peripheral CT angiography: do we still need axial images?
Schernthaner RE, Wolf F, Mistelbauer G, Weber M, Sramek M, Groeller E, Loewe C
Clin Imaging 2015 Jul-Aug;39(4):603-7. Epub 2015 Mar 20 doi: 10.1016/j.clinimag.2015.03.005. PMID: 25825345
Limb salvage in women.
Huynh TT, Choi L
Methodist Debakey Cardiovasc J 2013 Apr;9(2):84-9. doi: 10.14797/mdcj-9-2-84. PMID: 23805340Free PMC Article
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Diagnosis

Utility of the cold pressor test to predict future cardiovascular events.
Pouwels S, Van Genderen ME, Kreeftenberg HG, Ribeiro R, Parmar C, Topal B, Celik A, Ugale S
Expert Rev Cardiovasc Ther 2019 Apr;17(4):305-318. Epub 2019 Apr 8 doi: 10.1080/14779072.2019.1598262. PMID: 30916592
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
From 3D to 4D: Integration of temporal information into CT angiography studies.
Haubenreisser H, Bigdeli A, Meyer M, Kremer T, Riester T, Kneser U, Schoenberg SO, Henzler T
Eur J Radiol 2015 Dec;84(12):2421-4. Epub 2015 Jun 18 doi: 10.1016/j.ejrad.2015.06.014. PMID: 26152869
Limb salvage in women.
Huynh TT, Choi L
Methodist Debakey Cardiovasc J 2013 Apr;9(2):84-9. doi: 10.14797/mdcj-9-2-84. PMID: 23805340Free PMC Article
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Therapy

Long Term Outcomes After Revascularisations Below the Knee with Paclitaxel Coated Devices: A Propensity Score Matched Cohort Analysis.
Heidemann F, Peters F, Kuchenbecker J, Kreutzburg T, Sedrakyan A, Marschall U, L'Hoest H, Debus ES, Behrendt CA
Eur J Vasc Endovasc Surg 2020 Oct;60(4):549-558. Epub 2020 Aug 14 doi: 10.1016/j.ejvs.2020.06.033. PMID: 32807674
Comparison of the Incidence of Complications and Secondary Surgical Interventions Necessary in Patients with Chronic Lower Limb Ischemia Treated by Both Open and Endovascular Surgeries.
Janczak D, Malinowski M, Bąkowski W, Krakowska K, Marschollek K, Marschollek P, Chabowski M
Ann Thorac Cardiovasc Surg 2017 Jun 20;23(3):135-140. Epub 2017 May 11 doi: 10.5761/atcs.oa.16-00282. PMID: 28496017Free PMC Article
Limb salvage in women.
Huynh TT, Choi L
Methodist Debakey Cardiovasc J 2013 Apr;9(2):84-9. doi: 10.14797/mdcj-9-2-84. PMID: 23805340Free PMC Article
Treating intermittent claudication with Tibetan medicine Padma 28: does it work?
Melzer J, Brignoli R, Diehm C, Reichling J, Do DD, Saller R
Atherosclerosis 2006 Nov;189(1):39-46. Epub 2006 Apr 4 doi: 10.1016/j.atherosclerosis.2006.02.042. PMID: 16600251
Cardiovascular effects of increasing hemoglobin in chronic renal failure.
Mayer G, Hörl WH
Am J Nephrol 1996;16(4):263-7. doi: 10.1159/000169007. PMID: 8739276

Prognosis

Common Iliac Artery to Below-Knee Popliteal Artery Bypass via Obturator Foramen in a Third-Time Reoperative Groin for Limb Salvage in Chronic Limb-Threatening Ischemia.
Pratt B, Thompson J, Peshel EC, Herur-Raman A, Nguyen BN, Lala S
Vasc Endovascular Surg 2023 Nov;57(8):905-908. Epub 2023 May 24 doi: 10.1177/15385744231178134. PMID: 37225280
Utility of the cold pressor test to predict future cardiovascular events.
Pouwels S, Van Genderen ME, Kreeftenberg HG, Ribeiro R, Parmar C, Topal B, Celik A, Ugale S
Expert Rev Cardiovasc Ther 2019 Apr;17(4):305-318. Epub 2019 Apr 8 doi: 10.1080/14779072.2019.1598262. PMID: 30916592
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
Classification of diabetic foot wounds.
Lavery LA, Armstrong DG, Harkless LB
Ostomy Wound Manage 1997 Mar;43(2):44-8, 50, 52-3. PMID: 9136997
Classification of diabetic foot wounds.
Lavery LA, Armstrong DG, Harkless LB
J Foot Ankle Surg 1996 Nov-Dec;35(6):528-31. doi: 10.1016/s1067-2516(96)80125-6. PMID: 8986890

Clinical prediction guides

Long Term Outcomes After Revascularisations Below the Knee with Paclitaxel Coated Devices: A Propensity Score Matched Cohort Analysis.
Heidemann F, Peters F, Kuchenbecker J, Kreutzburg T, Sedrakyan A, Marschall U, L'Hoest H, Debus ES, Behrendt CA
Eur J Vasc Endovasc Surg 2020 Oct;60(4):549-558. Epub 2020 Aug 14 doi: 10.1016/j.ejvs.2020.06.033. PMID: 32807674
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Late-stage non-anastomotic rupture of axillo-bifemoral bypass graft.
Shiraishi M, Kimura C, Takeuchi T, Muramatsu K
Ann Thorac Cardiovasc Surg 2012;18(5):485-7. Epub 2012 Mar 24 doi: 10.5761/atcs.cr.11.01818. PMID: 22446953
Classification of diabetic foot wounds.
Lavery LA, Armstrong DG, Harkless LB
Ostomy Wound Manage 1997 Mar;43(2):44-8, 50, 52-3. PMID: 9136997
Classification of diabetic foot wounds.
Lavery LA, Armstrong DG, Harkless LB
J Foot Ankle Surg 1996 Nov-Dec;35(6):528-31. doi: 10.1016/s1067-2516(96)80125-6. PMID: 8986890

Recent systematic reviews

Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review.
Hischke S, Rieß HC, Bublitz MK, Kriston L, Schwaneberg T, Härter M, Bertges D, S Debus E, Behrendt CA
Eur J Vasc Endovasc Surg 2019 Nov;58(5):738-745. Epub 2019 Sep 13 doi: 10.1016/j.ejvs.2019.06.029. PMID: 31526633
The Association of Periodontitis and Peripheral Arterial Occlusive Disease-A Systematic Review.
Kaschwich M, Behrendt CA, Heydecke G, Bayer A, Debus ES, Seedorf U, Aarabi G
Int J Mol Sci 2019 Jun 15;20(12) doi: 10.3390/ijms20122936. PMID: 31208079Free PMC Article
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD000095. doi: 10.1002/14651858.CD000095.pub2. PMID: 23633303Free PMC Article
Subintimal angioplasty for peripheral arterial occlusive disease: a systematic review.
Met R, Van Lienden KP, Koelemay MJ, Bipat S, Legemate DA, Reekers JA
Cardiovasc Intervent Radiol 2008 Jul-Aug;31(4):687-97. Epub 2008 Apr 15 doi: 10.1007/s00270-008-9331-7. PMID: 18414946Free PMC Article
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2000;(2):CD000095. doi: 10.1002/14651858.CD000095. PMID: 10796487

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