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Peripheral arterial occlusive disease

MedGen UID:
266302
•Concept ID:
C1306889
•
Disease or Syndrome
Synonym: peripheral arterial occlusive disease
SNOMED CT: Peripheral arterial occlusive disease (399957001); PAOD - Peripheral arterial occlusive disease (399957001); Peripheral artery occlusive disease (399957001)

Definition

Disorder caused by the occlusion of the lumen of the peripheral arteries. Causes include atherosclerosis, inflammatory processes, thrombosis, and embolism. The arterial occlusion results in chronic or acute pain usually in the lower limbs due to muscle ischemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral arterial occlusive disease

Professional guidelines

PubMed

Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
The SELUTION SLR™ drug-eluting balloon system for the treatment of symptomatic femoropopliteal lesions.
Böhme T, Noory E, Beschorner U, Macharzina R, Zeller T
Future Cardiol 2021 Mar;17(2):257-267. Epub 2020 Aug 20 doi: 10.2217/fca-2020-0085. PMID: 32815739
Optimal management of infrainguinal arterial occlusive disease.
Pennywell DJ, Tan TW, Zhang WW
Vasc Health Risk Manag 2014;10:599-608. Epub 2014 Oct 24 doi: 10.2147/VHRM.S50779. PMID: 25368519Free PMC Article

Recent clinical studies

Etiology

Exercise Training for Patients With Peripheral Arterial Occlusive Disease.
Ingwersen M, Kunstmann I, Oswald C, Best N, Weisser B, Teichgräber U
Dtsch Arztebl Int 2023 Dec 27;120(51-52):879-885. doi: 10.3238/arztebl.m2023.0231. PMID: 38019155Free PMC Article
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Diagnosis

Neutral effects of SGLT2 inhibitors in acute coronary syndromes, peripheral arterial occlusive disease, or ischemic stroke: a meta-analysis of randomized controlled trials.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH, Yeh YH
Cardiovasc Diabetol 2023 Mar 13;22(1):57. doi: 10.1186/s12933-023-01789-5. PMID: 36915157Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271
Diabetic foot ulcers: prevention, diagnosis and classification.
Armstrong DG, Lavery LA
Am Fam Physician 1998 Mar 15;57(6):1325-32, 1337-8. PMID: 9531915

Therapy

Exercise Training for Patients With Peripheral Arterial Occlusive Disease.
Ingwersen M, Kunstmann I, Oswald C, Best N, Weisser B, Teichgräber U
Dtsch Arztebl Int 2023 Dec 27;120(51-52):879-885. doi: 10.3238/arztebl.m2023.0231. PMID: 38019155Free PMC Article
Neutral effects of SGLT2 inhibitors in acute coronary syndromes, peripheral arterial occlusive disease, or ischemic stroke: a meta-analysis of randomized controlled trials.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH, Yeh YH
Cardiovasc Diabetol 2023 Mar 13;22(1):57. doi: 10.1186/s12933-023-01789-5. PMID: 36915157Free PMC Article
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271

Prognosis

Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
The Charcot foot: pathophysiology, diagnosis and classification.
Trieb K
Bone Joint J 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038. PMID: 27587513
HIV-occlusive vascular disease.
van Marle J, Mistry PP, Botes K
S Afr J Surg 2009 May;47(2):36-42. PMID: 19626778
Subintimal angioplasty for peripheral arterial occlusive disease: a systematic review.
Met R, Van Lienden KP, Koelemay MJ, Bipat S, Legemate DA, Reekers JA
Cardiovasc Intervent Radiol 2008 Jul-Aug;31(4):687-97. Epub 2008 Apr 15 doi: 10.1007/s00270-008-9331-7. PMID: 18414946Free PMC Article
Peripheral arterial occlusive disease.
Minar E
Vasa 2007 Aug;36(3):155-64. doi: 10.1024/0301-1526.36.3.155. PMID: 18019271

Clinical prediction guides

Treating Peripheral Arterial Occlusive Disease and Acute Limb Ischemia During a COVID-19 Pandemic in 2020.
Exelmans W, Knaapen L, Boonman-de Winter L, Vriens P, van der Laan L
Ann Vasc Surg 2022 Aug;84:1-5. Epub 2022 Jan 31 doi: 10.1016/j.avsg.2022.01.012. PMID: 35108551Free PMC Article
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease.
Hardung D, Behne A, Boral M, Giesche C, Langhoff R
Dtsch Arztebl Int 2021 Aug 9;118(31-32):528-535. doi: 10.3238/arztebl.m2021.0157. PMID: 33734081Free PMC Article
Peripheral arterial occlusive disease and perioperative risk.
Poredos P, Poredos P
Int Angiol 2018 Apr;37(2):93-99. Epub 2018 Jan 11 doi: 10.23736/S0392-9590.18.03897-X. PMID: 29327897
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD000095. doi: 10.1002/14651858.CD000095.pub2. PMID: 23633303Free PMC Article
HIV-occlusive vascular disease.
van Marle J, Mistry PP, Botes K
S Afr J Surg 2009 May;47(2):36-42. PMID: 19626778

Recent systematic reviews

Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review.
Hischke S, Rieß HC, Bublitz MK, Kriston L, Schwaneberg T, Härter M, Bertges D, S Debus E, Behrendt CA
Eur J Vasc Endovasc Surg 2019 Nov;58(5):738-745. Epub 2019 Sep 13 doi: 10.1016/j.ejvs.2019.06.029. PMID: 31526633
The Association of Periodontitis and Peripheral Arterial Occlusive Disease-A Systematic Review.
Kaschwich M, Behrendt CA, Heydecke G, Bayer A, Debus ES, Seedorf U, Aarabi G
Int J Mol Sci 2019 Jun 15;20(12) doi: 10.3390/ijms20122936. PMID: 31208079Free PMC Article
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2013 Apr 30;2013(4):CD000095. doi: 10.1002/14651858.CD000095.pub2. PMID: 23633303Free PMC Article
Subintimal angioplasty for peripheral arterial occlusive disease: a systematic review.
Met R, Van Lienden KP, Koelemay MJ, Bipat S, Legemate DA, Reekers JA
Cardiovasc Intervent Radiol 2008 Jul-Aug;31(4):687-97. Epub 2008 Apr 15 doi: 10.1007/s00270-008-9331-7. PMID: 18414946Free PMC Article
Garlic for peripheral arterial occlusive disease.
Jepson RG, Kleijnen J, Leng GC
Cochrane Database Syst Rev 2000;(2):CD000095. doi: 10.1002/14651858.CD000095. PMID: 10796487

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