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Bartholin gland small cell carcinoma

MedGen UID:
267705
•Concept ID:
C1511051
•
Neoplastic Process
Synonyms: Bartholin Gland Small Cell Carcinoma; Bartholin Gland Small Cell Neuroendocrine Carcinoma; Bartholin's Gland Small Cell Carcinoma; Bartholin's gland small cell carcinoma; major vestibular gland small cell carcinoma; small cell carcinoma of major vestibular gland
 
Monarch Initiative: MONDO:0004120

Definition

A rare small cell neuroendocrine carcinoma that arises from the Bartholin gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBartholin gland small cell carcinoma

Recent clinical studies

Etiology

Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome.
Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB
Int J Gynecol Pathol 2019 Mar;38(2):189-195. doi: 10.1097/PGP.0000000000000489. PMID: 29406447
Primary treatment of Bartholin's gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases.
López-Varela E, Oliva E, McIntyre JF, Fuller AF Jr
Int J Gynecol Cancer 2007 May-Jun;17(3):661-7. doi: 10.1111/j.1525-1438.2006.00781.x. PMID: 17504379
Primary Bartholin gland carcinoma: a report of seven cases.
Obermair A, Koller S, Crandon AJ, Perrin L, Nicklin JL
Aust N Z J Obstet Gynaecol 2001 Feb;41(1):78-81. doi: 10.1111/j.1479-828x.2001.tb01299.x. PMID: 11284653
Primary reconstructive surgery with a sliding flap for carcinoma of the Bartholin gland.
Larson B, Palmer B, Flam F
Eur J Gynaecol Oncol 1998;19(5):464-5. PMID: 9863913
Pathology of the vagina.
Wilkinson EJ
Curr Opin Obstet Gynecol 1991 Aug;3(4):553-60. PMID: 1678972

Diagnosis

A rare case of primary small cell neuroendocrine carcinoma of the Bartholin gland.
Han L, Zheng A, Chen Y
Int J Gynaecol Obstet 2021 Dec;155(3):539-540. Epub 2021 Jul 3 doi: 10.1002/ijgo.13782. PMID: 34115878
Merkel cell carcinoma of the Bartholin's gland.
Khoury-Collado F, Elliott KS, Lee YC, Chen PC, Abulafia O
Gynecol Oncol 2005 Jun;97(3):928-31. doi: 10.1016/j.ygyno.2004.12.064. PMID: 15885760
Primary Bartholin gland carcinoma: a report of seven cases.
Obermair A, Koller S, Crandon AJ, Perrin L, Nicklin JL
Aust N Z J Obstet Gynaecol 2001 Feb;41(1):78-81. doi: 10.1111/j.1479-828x.2001.tb01299.x. PMID: 11284653
Vaginal small cell carcinoma mimicking a Bartholin's gland abscess: a case report.
Mirhashemi R, Kratz A, Weir MM, Molpus KL, Goodman AK
Gynecol Oncol 1998 Mar;68(3):297-300. doi: 10.1006/gyno.1998.4959. PMID: 9570984
Pathology of the vagina.
Wilkinson EJ
Curr Opin Obstet Gynecol 1991 Aug;3(4):553-60. PMID: 1678972

Therapy

Primary vulvar Ewing's sarcoma/primitive neuroectodermal tumor in a post-menopausal woman: a case report.
Boldorini R, Riboni F, Cristina S, Allegrini S, Valentini S, Muscarà M, Ruspa G
Pathol Res Pract 2010 Jul 15;206(7):476-9. Epub 2009 Aug 4 doi: 10.1016/j.prp.2009.07.006. PMID: 19656640
Hyperbaric oxygen therapy following radical vulvectomy: an adjunctive therapy to improve wound healing.
Reedy MB, Capen CV, Baker DP, Petersen WG, Kuehl TJ
Gynecol Oncol 1994 Apr;53(1):13-6. doi: 10.1006/gyno.1994.1079. PMID: 8175014

Prognosis

Brain Metastasis From Bartholin Gland Carcinoma.
Jamshidi AM, Eichberg DG, Gultekin S, Komotar RJ
World Neurosurg 2020 Nov;143:280-284. Epub 2020 Jul 28 doi: 10.1016/j.wneu.2020.07.122. PMID: 32736128
Primary reconstructive surgery with a sliding flap for carcinoma of the Bartholin gland.
Larson B, Palmer B, Flam F
Eur J Gynaecol Oncol 1998;19(5):464-5. PMID: 9863913

Clinical prediction guides

Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome.
Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB
Int J Gynecol Pathol 2019 Mar;38(2):189-195. doi: 10.1097/PGP.0000000000000489. PMID: 29406447
Hyperbaric oxygen therapy following radical vulvectomy: an adjunctive therapy to improve wound healing.
Reedy MB, Capen CV, Baker DP, Petersen WG, Kuehl TJ
Gynecol Oncol 1994 Apr;53(1):13-6. doi: 10.1006/gyno.1994.1079. PMID: 8175014

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